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Pre-attentive spectro-temporal feature processing in the human auditory system.
Brain Topogr. 2009 Sep; 22(2):97-108.BT

Abstract

In the present study, we investigated the pre-attentive processing of low-level acoustic properties and the impact of this mechanism on functional lateralization in the human auditory system. Mismatch negativity (MMN) of the event-related potentials (ERP) were recorded in 19 adult humans who passively listened to a standard stimulus and spectrally and temporally deviant sounds. We predicted modulations of the MMN amplitude in response to spectrally and temporally graded deviants. Based on recent models of functional hemispheric lateralisation, we further hypothesized a left-lateralized source of the MMN in response to temporal deviants and, in contrast, a right-lateralized source of the MMN in response to spectral deviants. In agreement with our hypothesis, we showed that spectrally and temporally deviant sounds lead to robust MMNs recorded from frontocentral scalp electrodes. The amplitudes of the MMNs were modulated by the grade of spectral and temporal deviation from the standard sound. Furthermore, by using an assumption-free source localization approach (LORETA) we demonstrated functionally lateralized activations with dominance of the right hemisphere for the processing of spectral characteristics and of the left hemisphere for the processing of temporal acoustic properties. Results of our study further contribute to the ongoing debate on the role of low-level acoustic feature perception in functional hemispheric lateralization in the context of auditory and speech processing. Our data indicate that the pre-attentive feature-specific deviant processing is mediated by partly distinct neural subsystems for temporal and spectral information.

Authors+Show Affiliations

Department of Biological Psychology, Otto-von-Guericke University, Magdeburg, Germany. tino.zaehle@ovgu.deNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19266276

Citation

Zaehle, Tino, et al. "Pre-attentive Spectro-temporal Feature Processing in the Human Auditory System." Brain Topography, vol. 22, no. 2, 2009, pp. 97-108.
Zaehle T, Jancke L, Herrmann CS, et al. Pre-attentive spectro-temporal feature processing in the human auditory system. Brain Topogr. 2009;22(2):97-108.
Zaehle, T., Jancke, L., Herrmann, C. S., & Meyer, M. (2009). Pre-attentive spectro-temporal feature processing in the human auditory system. Brain Topography, 22(2), 97-108. https://doi.org/10.1007/s10548-009-0085-6
Zaehle T, et al. Pre-attentive Spectro-temporal Feature Processing in the Human Auditory System. Brain Topogr. 2009;22(2):97-108. PubMed PMID: 19266276.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pre-attentive spectro-temporal feature processing in the human auditory system. AU - Zaehle,Tino, AU - Jancke,Lutz, AU - Herrmann,Christoph S, AU - Meyer,Martin, Y1 - 2009/03/06/ PY - 2008/06/18/received PY - 2009/02/18/accepted PY - 2009/3/7/entrez PY - 2009/3/7/pubmed PY - 2009/10/6/medline SP - 97 EP - 108 JF - Brain topography JO - Brain Topogr VL - 22 IS - 2 N2 - In the present study, we investigated the pre-attentive processing of low-level acoustic properties and the impact of this mechanism on functional lateralization in the human auditory system. Mismatch negativity (MMN) of the event-related potentials (ERP) were recorded in 19 adult humans who passively listened to a standard stimulus and spectrally and temporally deviant sounds. We predicted modulations of the MMN amplitude in response to spectrally and temporally graded deviants. Based on recent models of functional hemispheric lateralisation, we further hypothesized a left-lateralized source of the MMN in response to temporal deviants and, in contrast, a right-lateralized source of the MMN in response to spectral deviants. In agreement with our hypothesis, we showed that spectrally and temporally deviant sounds lead to robust MMNs recorded from frontocentral scalp electrodes. The amplitudes of the MMNs were modulated by the grade of spectral and temporal deviation from the standard sound. Furthermore, by using an assumption-free source localization approach (LORETA) we demonstrated functionally lateralized activations with dominance of the right hemisphere for the processing of spectral characteristics and of the left hemisphere for the processing of temporal acoustic properties. Results of our study further contribute to the ongoing debate on the role of low-level acoustic feature perception in functional hemispheric lateralization in the context of auditory and speech processing. Our data indicate that the pre-attentive feature-specific deviant processing is mediated by partly distinct neural subsystems for temporal and spectral information. SN - 1573-6792 UR - https://www.unboundmedicine.com/medline/citation/19266276/Pre_attentive_spectro_temporal_feature_processing_in_the_human_auditory_system_ L2 - https://doi.org/10.1007/s10548-009-0085-6 DB - PRIME DP - Unbound Medicine ER -