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Molecularly imprinted polymers: an analytical tool for the determination of benzimidazole compounds in water samples.
Talanta. 2009 May 15; 78(3):1029-35.T

Abstract

Molecularly imprinted polymers (MIPs) for benzimidazole compounds have been synthesized by precipitation polymerization using thiabendazole (TBZ) as template, methacrylic acid as functional monomer, ethyleneglycol dimethacrylate (EDMA) and divinylbenzene (DVB) as cross-linkers and a mixture of acetonitrile and toluene as porogen. The experiments carried out by molecularly imprinted solid phase extraction (MISPE) in cartridges demonstrated the imprint effect in both imprinted polymers. MIP-DVB enabled a much higher breakthrough volume than MIP-EDMA, and thus was selected for further experiments. The ability of this MIP for the selective recognition of other benzimidazole compounds (albendazole, benomyl, carbendazim, fenbendazole, flubendazole and fuberidazole) was evaluated. The obtained results revealed the high selectivity of the imprinted polymer towards all the selected benzimidazole compounds. An off-line analytical methodology based on a MISPE procedure has been developed for the determination of benzimidazole compounds in tap, river and well water samples at concentration levels below the legislated maximum concentration levels (MCLs) with quantitative recoveries. Additionally, an on-line preconcentration procedure based on the use of a molecularly imprinted polymer as selective stationary phase in HPLC is proposed as a fast screening method for the evaluation of the presence of benzimidazole compounds in water samples.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Cacho C
Departamento de Química Analítica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Ciudad Universitaria s/n, 28040 Madrid, Spain.
Turiel E
No affiliation info available
Pérez-Conde C
No affiliation info available

MeSH

BenzimidazolesChromatography, High Pressure LiquidFresh WaterMolecular ImprintingPolymersSolid Phase Extraction

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19269468

Citation

Cacho, Carmen, et al. "Molecularly Imprinted Polymers: an Analytical Tool for the Determination of Benzimidazole Compounds in Water Samples." Talanta, vol. 78, no. 3, 2009, pp. 1029-35.
Cacho C, Turiel E, Pérez-Conde C. Molecularly imprinted polymers: an analytical tool for the determination of benzimidazole compounds in water samples. Talanta. 2009;78(3):1029-35.
Cacho, C., Turiel, E., & Pérez-Conde, C. (2009). Molecularly imprinted polymers: an analytical tool for the determination of benzimidazole compounds in water samples. Talanta, 78(3), 1029-35. https://doi.org/10.1016/j.talanta.2009.01.007
Cacho C, Turiel E, Pérez-Conde C. Molecularly Imprinted Polymers: an Analytical Tool for the Determination of Benzimidazole Compounds in Water Samples. Talanta. 2009 May 15;78(3):1029-35. PubMed PMID: 19269468.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Molecularly imprinted polymers: an analytical tool for the determination of benzimidazole compounds in water samples. AU - Cacho,Carmen, AU - Turiel,Esther, AU - Pérez-Conde,Concepción, Y1 - 2009/01/20/ PY - 2008/10/03/received PY - 2008/12/23/revised PY - 2009/01/09/accepted PY - 2009/3/10/entrez PY - 2009/3/10/pubmed PY - 2009/4/30/medline SP - 1029 EP - 35 JF - Talanta JO - Talanta VL - 78 IS - 3 N2 - Molecularly imprinted polymers (MIPs) for benzimidazole compounds have been synthesized by precipitation polymerization using thiabendazole (TBZ) as template, methacrylic acid as functional monomer, ethyleneglycol dimethacrylate (EDMA) and divinylbenzene (DVB) as cross-linkers and a mixture of acetonitrile and toluene as porogen. The experiments carried out by molecularly imprinted solid phase extraction (MISPE) in cartridges demonstrated the imprint effect in both imprinted polymers. MIP-DVB enabled a much higher breakthrough volume than MIP-EDMA, and thus was selected for further experiments. The ability of this MIP for the selective recognition of other benzimidazole compounds (albendazole, benomyl, carbendazim, fenbendazole, flubendazole and fuberidazole) was evaluated. The obtained results revealed the high selectivity of the imprinted polymer towards all the selected benzimidazole compounds. An off-line analytical methodology based on a MISPE procedure has been developed for the determination of benzimidazole compounds in tap, river and well water samples at concentration levels below the legislated maximum concentration levels (MCLs) with quantitative recoveries. Additionally, an on-line preconcentration procedure based on the use of a molecularly imprinted polymer as selective stationary phase in HPLC is proposed as a fast screening method for the evaluation of the presence of benzimidazole compounds in water samples. SN - 1873-3573 UR - https://www.unboundmedicine.com/medline/citation/19269468/Molecularly_imprinted_polymers:_an_analytical_tool_for_the_determination_of_benzimidazole_compounds_in_water_samples_ DB - PRIME DP - Unbound Medicine ER -