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Short report: Development of post-kala-azar dermal leishmaniasis (PKDL) in miltefosine-treated visceral leishmaniasis.
Am J Trop Med Hyg. 2009 Mar; 80(3):336-8.AJ

Abstract

We report two cases of post-kala-azar dermal leishmaniasis (PKDL), which had subsequently developed after successful treatment of visceral leishmaniasis with miltefosine. Both patients had maculo-nodular lesions all over the body, and they were diagnosed as PKDL by parasitologic examination for Leishmania donovani bodies in a skin snip of lesions. Patients were put on amphotericin B and responded very well for nodular lesions with one course of treatment. However, longer duration of the treatment is needed for total clearance of macular lesions from body surface in PKDL cases. This is the first case report of PKDL in India, which developed after successful treatment of visceral leishmaniasis with miltefosine.

Authors+Show Affiliations

Division of Clinical Medicine, Rajendra Memorial Research Institute of Medical Sciences (Indian Council of Medical Research), Agamkuan, Patna, Bihar, India. drkrishnapandey@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

19270277

Citation

Das, Vidya Nand Rabi, et al. "Short Report: Development of Post-kala-azar Dermal Leishmaniasis (PKDL) in Miltefosine-treated Visceral Leishmaniasis." The American Journal of Tropical Medicine and Hygiene, vol. 80, no. 3, 2009, pp. 336-8.
Das VN, Pandey K, Verma N, et al. Short report: Development of post-kala-azar dermal leishmaniasis (PKDL) in miltefosine-treated visceral leishmaniasis. Am J Trop Med Hyg. 2009;80(3):336-8.
Das, V. N., Pandey, K., Verma, N., Lal, C. S., Bimal, S., Topno, R. K., Singh, D., Siddiqui, N. A., Verma, R. B., & Das, P. (2009). Short report: Development of post-kala-azar dermal leishmaniasis (PKDL) in miltefosine-treated visceral leishmaniasis. The American Journal of Tropical Medicine and Hygiene, 80(3), 336-8.
Das VN, et al. Short Report: Development of Post-kala-azar Dermal Leishmaniasis (PKDL) in Miltefosine-treated Visceral Leishmaniasis. Am J Trop Med Hyg. 2009;80(3):336-8. PubMed PMID: 19270277.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Short report: Development of post-kala-azar dermal leishmaniasis (PKDL) in miltefosine-treated visceral leishmaniasis. AU - Das,Vidya Nand Rabi, AU - Pandey,Krishna, AU - Verma,Neena, AU - Lal,Chandra Shekhar, AU - Bimal,Sanjeev, AU - Topno,Roshan Kamal, AU - Singh,Dharmendra, AU - Siddiqui,Niyamat Ali, AU - Verma,Rakesh Bihari, AU - Das,Pradeep, PY - 2009/3/10/entrez PY - 2009/3/10/pubmed PY - 2009/3/31/medline SP - 336 EP - 8 JF - The American journal of tropical medicine and hygiene JO - Am J Trop Med Hyg VL - 80 IS - 3 N2 - We report two cases of post-kala-azar dermal leishmaniasis (PKDL), which had subsequently developed after successful treatment of visceral leishmaniasis with miltefosine. Both patients had maculo-nodular lesions all over the body, and they were diagnosed as PKDL by parasitologic examination for Leishmania donovani bodies in a skin snip of lesions. Patients were put on amphotericin B and responded very well for nodular lesions with one course of treatment. However, longer duration of the treatment is needed for total clearance of macular lesions from body surface in PKDL cases. This is the first case report of PKDL in India, which developed after successful treatment of visceral leishmaniasis with miltefosine. SN - 1476-1645 UR - https://www.unboundmedicine.com/medline/citation/19270277/Short_report:_Development_of_post_kala_azar_dermal_leishmaniasis__PKDL__in_miltefosine_treated_visceral_leishmaniasis_ L2 - http://www.diseaseinfosearch.org/result/4166 DB - PRIME DP - Unbound Medicine ER -