Prevalence of metabolic syndrome by the Adult Treatment Panel III, International Diabetes Federation, and World Health Organization definitions and their association with coronary heart disease in an elderly Iranian population.Ann Acad Med Singapore 2009; 38(2):142-9AA
Abstract
INTRODUCTION
To determine the prevalence of the metabolic syndrome (MS) in an Iranian elderly population and show its association with coronary heart disease (CHD).
MATERIALS AND METHODS
This is a cross-sectional study on 720 Iranian men and women aged > or = 65 years who participated in the Tehran Lipid and Glucose Study (TLGS). Logistic regression analysis was used to estimate the odds ratio (OR) of developing CHD in model 1, an age-adjusted model; model 2, adjusted for age, smoking status, premature history of CHD and low-density lipoprotein (LDL) cholesterol; and model 3, adjusted for mentioned variables plus the MS components.
RESULTS
The prevalence of MS was 50.8%, 41.8% and 41.9% based on the Adult Treatment Panel (ATPIII), the World Health Organisation (WHO), and the International Diabetes Federation (IDF) definitions, respectively. The IDF definition showed high agreement with the ATPIII definition. Age-adjusted OR (95% CI) of the MS for CHD was 1.6 (1.2 to 2.2) by both the ATPIII and WHO definitions and 1.4 (1.0 to 1.9) by the IDF definition. IDF-defined MS lost its association with CHD in model 2. In model 3, obesity (WHO definition) and high blood pressure (ATPIII and WHO definitions) were associated with CHD.
CONCLUSIONS
In an elderly Iranian population MS is highly prevalent. ATPIII and WHO definitions seem to be more pertinent than IDF for screening CHD risk. None of these definitions showed association with CHD when considering their components.
Links
MeSH
Pub Type(s)
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Language
eng
PubMed ID
19271043
Citation
Hadaegh, Farzad, et al. "Prevalence of Metabolic Syndrome By the Adult Treatment Panel III, International Diabetes Federation, and World Health Organization Definitions and Their Association With Coronary Heart Disease in an Elderly Iranian Population." Annals of the Academy of Medicine, Singapore, vol. 38, no. 2, 2009, pp. 142-9.
Hadaegh F, Zabetian A, Tohidi M, et al. Prevalence of metabolic syndrome by the Adult Treatment Panel III, International Diabetes Federation, and World Health Organization definitions and their association with coronary heart disease in an elderly Iranian population. Ann Acad Med Singap. 2009;38(2):142-9.
Hadaegh, F., Zabetian, A., Tohidi, M., Ghasemi, A., Sheikholeslami, F., & Azizi, F. (2009). Prevalence of metabolic syndrome by the Adult Treatment Panel III, International Diabetes Federation, and World Health Organization definitions and their association with coronary heart disease in an elderly Iranian population. Annals of the Academy of Medicine, Singapore, 38(2), pp. 142-9.
Hadaegh F, et al. Prevalence of Metabolic Syndrome By the Adult Treatment Panel III, International Diabetes Federation, and World Health Organization Definitions and Their Association With Coronary Heart Disease in an Elderly Iranian Population. Ann Acad Med Singap. 2009;38(2):142-9. PubMed PMID: 19271043.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Prevalence of metabolic syndrome by the Adult Treatment Panel III, International Diabetes Federation, and World Health Organization definitions and their association with coronary heart disease in an elderly Iranian population.
AU - Hadaegh,Farzad,
AU - Zabetian,Azadeh,
AU - Tohidi,Maryam,
AU - Ghasemi,Asghar,
AU - Sheikholeslami,Farhad,
AU - Azizi,Fereidoun,
PY - 2009/3/10/entrez
PY - 2009/3/10/pubmed
PY - 2009/6/3/medline
SP - 142
EP - 9
JF - Annals of the Academy of Medicine, Singapore
JO - Ann. Acad. Med. Singap.
VL - 38
IS - 2
N2 - INTRODUCTION: To determine the prevalence of the metabolic syndrome (MS) in an Iranian elderly population and show its association with coronary heart disease (CHD). MATERIALS AND METHODS: This is a cross-sectional study on 720 Iranian men and women aged > or = 65 years who participated in the Tehran Lipid and Glucose Study (TLGS). Logistic regression analysis was used to estimate the odds ratio (OR) of developing CHD in model 1, an age-adjusted model; model 2, adjusted for age, smoking status, premature history of CHD and low-density lipoprotein (LDL) cholesterol; and model 3, adjusted for mentioned variables plus the MS components. RESULTS: The prevalence of MS was 50.8%, 41.8% and 41.9% based on the Adult Treatment Panel (ATPIII), the World Health Organisation (WHO), and the International Diabetes Federation (IDF) definitions, respectively. The IDF definition showed high agreement with the ATPIII definition. Age-adjusted OR (95% CI) of the MS for CHD was 1.6 (1.2 to 2.2) by both the ATPIII and WHO definitions and 1.4 (1.0 to 1.9) by the IDF definition. IDF-defined MS lost its association with CHD in model 2. In model 3, obesity (WHO definition) and high blood pressure (ATPIII and WHO definitions) were associated with CHD. CONCLUSIONS: In an elderly Iranian population MS is highly prevalent. ATPIII and WHO definitions seem to be more pertinent than IDF for screening CHD risk. None of these definitions showed association with CHD when considering their components.
SN - 0304-4602
UR - https://www.unboundmedicine.com/medline/citation/19271043/Prevalence_of_metabolic_syndrome_by_the_Adult_Treatment_Panel_III_International_Diabetes_Federation_and_World_Health_Organization_definitions_and_their_association_with_coronary_heart_disease_in_an_elderly_Iranian_population_
L2 - http://www.annals.edu.sg/pdf/38VolNo2Feb2009/V38N2p142.pdf
DB - PRIME
DP - Unbound Medicine
ER -
