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Prevalence, severity, and symptom bother of lower urinary tract symptoms among men in the EPIC study: impact of overactive bladder.
Eur Urol. 2009 Jul; 56(1):14-20.EU

Abstract

BACKGROUND

Lower urinary tract symptoms (LUTS) are prevalent among men.

OBJECTIVE

To describe the prevalence, severity, and symptom bother of LUTS in all men and men with overactive bladder (OAB) symptoms in the EPIC study.

DESIGN, SETTING, AND PARTICIPANTS

A secondary analysis of data from EPIC, a multinational population-based survey of 19,165 adults, was performed. Current International Continence Society definitions were used for individual LUTS and OAB; OAB cases were defined as men reporting urgency.

MEASUREMENTS

Participants were asked about the presence of individual LUTS and associated symptom bother. LUTS severity was measured using the International Prostate Symptom Score (IPSS).

RESULTS AND LIMITATIONS

There was substantial overlap of storage, voiding, and postmicturition symptoms among all men (n=7210) and in men with OAB symptoms (n=502); men with OAB symptoms were more likely to experience multiple LUTS subtypes. Among both populations, nocturia was the most commonly reported symptom, except for urgency (the hallmark symptom) among men with OAB symptoms; terminal dribble and sensation of incomplete emptying were the most common voiding and postmicturition symptoms. The prevalence of all LUTS increased with age among the general population; only storage LUTS increased with age among men with OAB symptoms. Number of LUTS and mean IPSS increased with age in both populations but were higher among men with OAB symptoms at all ages; the proportion reporting moderate-severe LUTS was higher than the general population (30% vs 6%). The proportion of men with OAB symptoms reporting symptom bother increased with urgency severity and severity and number of LUTS. LUTS severity may have been underestimated by the IPSS, which does not assess incontinence.

CONCLUSIONS

Men with LUTS commonly experience coexisting storage, voiding, and postmicturition symptoms, emphasizing the need for comprehensive urologic assessments. Men with OAB symptoms reported more LUTS and greater severity than the general population. Symptom bother was related to number of LUTS and urgency severity.

Authors+Show Affiliations

Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27599, USA. dirwin@email.unc.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19278775

Citation

Irwin, Debra E., et al. "Prevalence, Severity, and Symptom Bother of Lower Urinary Tract Symptoms Among Men in the EPIC Study: Impact of Overactive Bladder." European Urology, vol. 56, no. 1, 2009, pp. 14-20.
Irwin DE, Milsom I, Kopp Z, et al. Prevalence, severity, and symptom bother of lower urinary tract symptoms among men in the EPIC study: impact of overactive bladder. Eur Urol. 2009;56(1):14-20.
Irwin, D. E., Milsom, I., Kopp, Z., Abrams, P., Artibani, W., & Herschorn, S. (2009). Prevalence, severity, and symptom bother of lower urinary tract symptoms among men in the EPIC study: impact of overactive bladder. European Urology, 56(1), 14-20. https://doi.org/10.1016/j.eururo.2009.02.026
Irwin DE, et al. Prevalence, Severity, and Symptom Bother of Lower Urinary Tract Symptoms Among Men in the EPIC Study: Impact of Overactive Bladder. Eur Urol. 2009;56(1):14-20. PubMed PMID: 19278775.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence, severity, and symptom bother of lower urinary tract symptoms among men in the EPIC study: impact of overactive bladder. AU - Irwin,Debra E, AU - Milsom,Ian, AU - Kopp,Zoe, AU - Abrams,Paul, AU - Artibani,Walter, AU - Herschorn,Sender, Y1 - 2009/03/03/ PY - 2008/11/21/received PY - 2009/02/18/accepted PY - 2009/3/13/entrez PY - 2009/3/13/pubmed PY - 2010/4/3/medline SP - 14 EP - 20 JF - European urology JO - Eur Urol VL - 56 IS - 1 N2 - BACKGROUND: Lower urinary tract symptoms (LUTS) are prevalent among men. OBJECTIVE: To describe the prevalence, severity, and symptom bother of LUTS in all men and men with overactive bladder (OAB) symptoms in the EPIC study. DESIGN, SETTING, AND PARTICIPANTS: A secondary analysis of data from EPIC, a multinational population-based survey of 19,165 adults, was performed. Current International Continence Society definitions were used for individual LUTS and OAB; OAB cases were defined as men reporting urgency. MEASUREMENTS: Participants were asked about the presence of individual LUTS and associated symptom bother. LUTS severity was measured using the International Prostate Symptom Score (IPSS). RESULTS AND LIMITATIONS: There was substantial overlap of storage, voiding, and postmicturition symptoms among all men (n=7210) and in men with OAB symptoms (n=502); men with OAB symptoms were more likely to experience multiple LUTS subtypes. Among both populations, nocturia was the most commonly reported symptom, except for urgency (the hallmark symptom) among men with OAB symptoms; terminal dribble and sensation of incomplete emptying were the most common voiding and postmicturition symptoms. The prevalence of all LUTS increased with age among the general population; only storage LUTS increased with age among men with OAB symptoms. Number of LUTS and mean IPSS increased with age in both populations but were higher among men with OAB symptoms at all ages; the proportion reporting moderate-severe LUTS was higher than the general population (30% vs 6%). The proportion of men with OAB symptoms reporting symptom bother increased with urgency severity and severity and number of LUTS. LUTS severity may have been underestimated by the IPSS, which does not assess incontinence. CONCLUSIONS: Men with LUTS commonly experience coexisting storage, voiding, and postmicturition symptoms, emphasizing the need for comprehensive urologic assessments. Men with OAB symptoms reported more LUTS and greater severity than the general population. Symptom bother was related to number of LUTS and urgency severity. SN - 1873-7560 UR - https://www.unboundmedicine.com/medline/citation/19278775/Prevalence_severity_and_symptom_bother_of_lower_urinary_tract_symptoms_among_men_in_the_EPIC_study:_impact_of_overactive_bladder_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0302-2838(09)00196-1 DB - PRIME DP - Unbound Medicine ER -