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Retinal and choroidal biometry in highly myopic eyes with spectral-domain optical coherence tomography.
Invest Ophthalmol Vis Sci 2009; 50(8):3876-80IO

Abstract

PURPOSE

Morphologic changes in the retina and choroid are closely related with high myopia-related diseases. This study was conducted to evaluate the morphologic characteristics of normal highly myopic eyes.

METHODS

Thirty-one phakic highly myopic eyes with no posterior abnormalities (18 patients; mean +/- SD age, 51.7 +/- 11.4 years) were enrolled. Retinal-choroidal thickness at the fovea 1.5 mm superiorly, inferiorly, nasally, and temporally and the choroidal curvature were measured in the 512 x 128 three-dimensional scan mode with spectral-domain optical coherence tomography. The degree of posterior staphyloma was determined as the sum of the vertical distance from the retinal pigment epithelial line beneath the fovea to the nasal, temporal, superior, and inferior edge of the image, including the fovea. The association of clinical data with these parameters was evaluated.

RESULTS

The mean +/- SD central retinal thickness was 200.9 +/- 39.3 microm. The mean choroidal thickness at the fovea (100.5 +/- 56.9 microm) was significantly different from the temporal (125.4 +/- 59.7 microm), nasal (81.9 +/- 35.0 microm), and superior (129.4 +/- 57.5 microm) thicknesses (P < 0.01). Central retinal thickness did not correlate with age, sex, refractive error, axial length, or central choroidal thickness. Central choroidal thickness was significantly associated with refractive error (P < 0.05) and posterior staphyloma height (P < 0.01). Posterior staphyloma height was significantly correlated with refractive error and axial length (P < 0.01). Stepwise analysis indicated that choroidal thickness correlated significantly with age and posterior staphyloma height (P < 0.01).

CONCLUSIONS

Posterior staphyloma formation was a key factor in choroidal thinning in highly myopic eyes. Choroidal thickness had a greater effect than retinal thickness in highly myopic eyes.

Authors+Show Affiliations

Department of Ophthalmology, Osaka University Medical School, Osaka Japan. ikuno@ophthal.med.osaka-u.ac.jpNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19279309

Citation

Ikuno, Yasushi, and Yasuo Tano. "Retinal and Choroidal Biometry in Highly Myopic Eyes With Spectral-domain Optical Coherence Tomography." Investigative Ophthalmology & Visual Science, vol. 50, no. 8, 2009, pp. 3876-80.
Ikuno Y, Tano Y. Retinal and choroidal biometry in highly myopic eyes with spectral-domain optical coherence tomography. Invest Ophthalmol Vis Sci. 2009;50(8):3876-80.
Ikuno, Y., & Tano, Y. (2009). Retinal and choroidal biometry in highly myopic eyes with spectral-domain optical coherence tomography. Investigative Ophthalmology & Visual Science, 50(8), pp. 3876-80. doi:10.1167/iovs.08-3325.
Ikuno Y, Tano Y. Retinal and Choroidal Biometry in Highly Myopic Eyes With Spectral-domain Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2009;50(8):3876-80. PubMed PMID: 19279309.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Retinal and choroidal biometry in highly myopic eyes with spectral-domain optical coherence tomography. AU - Ikuno,Yasushi, AU - Tano,Yasuo, Y1 - 2009/03/11/ PY - 2009/3/13/entrez PY - 2009/3/13/pubmed PY - 2009/8/12/medline SP - 3876 EP - 80 JF - Investigative ophthalmology & visual science JO - Invest. Ophthalmol. Vis. Sci. VL - 50 IS - 8 N2 - PURPOSE: Morphologic changes in the retina and choroid are closely related with high myopia-related diseases. This study was conducted to evaluate the morphologic characteristics of normal highly myopic eyes. METHODS: Thirty-one phakic highly myopic eyes with no posterior abnormalities (18 patients; mean +/- SD age, 51.7 +/- 11.4 years) were enrolled. Retinal-choroidal thickness at the fovea 1.5 mm superiorly, inferiorly, nasally, and temporally and the choroidal curvature were measured in the 512 x 128 three-dimensional scan mode with spectral-domain optical coherence tomography. The degree of posterior staphyloma was determined as the sum of the vertical distance from the retinal pigment epithelial line beneath the fovea to the nasal, temporal, superior, and inferior edge of the image, including the fovea. The association of clinical data with these parameters was evaluated. RESULTS: The mean +/- SD central retinal thickness was 200.9 +/- 39.3 microm. The mean choroidal thickness at the fovea (100.5 +/- 56.9 microm) was significantly different from the temporal (125.4 +/- 59.7 microm), nasal (81.9 +/- 35.0 microm), and superior (129.4 +/- 57.5 microm) thicknesses (P < 0.01). Central retinal thickness did not correlate with age, sex, refractive error, axial length, or central choroidal thickness. Central choroidal thickness was significantly associated with refractive error (P < 0.05) and posterior staphyloma height (P < 0.01). Posterior staphyloma height was significantly correlated with refractive error and axial length (P < 0.01). Stepwise analysis indicated that choroidal thickness correlated significantly with age and posterior staphyloma height (P < 0.01). CONCLUSIONS: Posterior staphyloma formation was a key factor in choroidal thinning in highly myopic eyes. Choroidal thickness had a greater effect than retinal thickness in highly myopic eyes. SN - 1552-5783 UR - https://www.unboundmedicine.com/medline/citation/19279309/Retinal_and_choroidal_biometry_in_highly_myopic_eyes_with_spectral_domain_optical_coherence_tomography_ L2 - http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.08-3325 DB - PRIME DP - Unbound Medicine ER -