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Beneficial cardiovascular effects of reducing exposure to particulate air pollution with a simple facemask.
Part Fibre Toxicol. 2009 Mar 13; 6:8.PF

Abstract

BACKGROUND

Exposure to air pollution is an important risk factor for cardiovascular morbidity and mortality, and is associated with increased blood pressure, reduced heart rate variability, endothelial dysfunction and myocardial ischaemia. Our objectives were to assess the cardiovascular effects of reducing air pollution exposure by wearing a facemask.

METHODS

In an open-label cross-over randomised controlled trial, 15 healthy volunteers (median age 28 years) walked on a predefined city centre route in Beijing in the presence and absence of a highly efficient facemask. Personal exposure to ambient air pollution and exercise was assessed continuously using portable real-time monitors and global positional system tracking respectively. Cardiovascular effects were assessed by continuous 12-lead electrocardiographic and ambulatory blood pressure monitoring.

RESULTS

Ambient exposure (PM2.5 86 +/- 61 vs 140 +/- 113 mug/m3; particle number 2.4 +/- 0.4 vs 2.3 +/- 0.4 x 104 particles/cm3), temperature (29 +/- 1 vs 28 +/- 3 degrees C) and relative humidity (63 +/- 10 vs 64 +/- 19%) were similar (P > 0.05 for all) on both study days. During the 2-hour city walk, systolic blood pressure was lower (114 +/- 10 vs 121 +/- 11 mmHg, P < 0.01) when subjects wore a facemask, although heart rate was similar (91 +/- 11 vs 88 +/- 11/min; P > 0.05). Over the 24-hour period heart rate variability increased (SDNN 65.6 +/- 11.5 vs 61.2 +/- 11.4 ms, P < 0.05; LF-power 919 +/- 352 vs 816 +/- 340 ms2, P < 0.05) when subjects wore the facemask.

CONCLUSION

Wearing a facemask appears to abrogate the adverse effects of air pollution on blood pressure and heart rate variability. This simple intervention has the potential to protect susceptible individuals and prevent cardiovascular events in cities with high concentrations of ambient air pollution.

Authors+Show Affiliations

Centre for Cardiovascular Sciences, Edinburgh University, Edinburgh, UK. jeremy.langrish@ed.ac.uk.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19284642

Citation

Langrish, Jeremy P., et al. "Beneficial Cardiovascular Effects of Reducing Exposure to Particulate Air Pollution With a Simple Facemask." Particle and Fibre Toxicology, vol. 6, 2009, p. 8.
Langrish JP, Mills NL, Chan JK, et al. Beneficial cardiovascular effects of reducing exposure to particulate air pollution with a simple facemask. Part Fibre Toxicol. 2009;6:8.
Langrish, J. P., Mills, N. L., Chan, J. K., Leseman, D. L., Aitken, R. J., Fokkens, P. H., Cassee, F. R., Li, J., Donaldson, K., Newby, D. E., & Jiang, L. (2009). Beneficial cardiovascular effects of reducing exposure to particulate air pollution with a simple facemask. Particle and Fibre Toxicology, 6, 8. https://doi.org/10.1186/1743-8977-6-8
Langrish JP, et al. Beneficial Cardiovascular Effects of Reducing Exposure to Particulate Air Pollution With a Simple Facemask. Part Fibre Toxicol. 2009 Mar 13;6:8. PubMed PMID: 19284642.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Beneficial cardiovascular effects of reducing exposure to particulate air pollution with a simple facemask. AU - Langrish,Jeremy P, AU - Mills,Nicholas L, AU - Chan,Julian Kk, AU - Leseman,Daan Lac, AU - Aitken,Robert J, AU - Fokkens,Paul Hb, AU - Cassee,Flemming R, AU - Li,Jing, AU - Donaldson,Ken, AU - Newby,David E, AU - Jiang,Lixin, Y1 - 2009/03/13/ PY - 2009/01/12/received PY - 2009/03/13/accepted PY - 2009/3/17/entrez PY - 2009/3/17/pubmed PY - 2009/3/17/medline SP - 8 EP - 8 JF - Particle and fibre toxicology JO - Part Fibre Toxicol VL - 6 N2 - BACKGROUND: Exposure to air pollution is an important risk factor for cardiovascular morbidity and mortality, and is associated with increased blood pressure, reduced heart rate variability, endothelial dysfunction and myocardial ischaemia. Our objectives were to assess the cardiovascular effects of reducing air pollution exposure by wearing a facemask. METHODS: In an open-label cross-over randomised controlled trial, 15 healthy volunteers (median age 28 years) walked on a predefined city centre route in Beijing in the presence and absence of a highly efficient facemask. Personal exposure to ambient air pollution and exercise was assessed continuously using portable real-time monitors and global positional system tracking respectively. Cardiovascular effects were assessed by continuous 12-lead electrocardiographic and ambulatory blood pressure monitoring. RESULTS: Ambient exposure (PM2.5 86 +/- 61 vs 140 +/- 113 mug/m3; particle number 2.4 +/- 0.4 vs 2.3 +/- 0.4 x 104 particles/cm3), temperature (29 +/- 1 vs 28 +/- 3 degrees C) and relative humidity (63 +/- 10 vs 64 +/- 19%) were similar (P > 0.05 for all) on both study days. During the 2-hour city walk, systolic blood pressure was lower (114 +/- 10 vs 121 +/- 11 mmHg, P < 0.01) when subjects wore a facemask, although heart rate was similar (91 +/- 11 vs 88 +/- 11/min; P > 0.05). Over the 24-hour period heart rate variability increased (SDNN 65.6 +/- 11.5 vs 61.2 +/- 11.4 ms, P < 0.05; LF-power 919 +/- 352 vs 816 +/- 340 ms2, P < 0.05) when subjects wore the facemask. CONCLUSION: Wearing a facemask appears to abrogate the adverse effects of air pollution on blood pressure and heart rate variability. This simple intervention has the potential to protect susceptible individuals and prevent cardiovascular events in cities with high concentrations of ambient air pollution. SN - 1743-8977 UR - https://www.unboundmedicine.com/medline/citation/19284642/full_citation L2 - https://particleandfibretoxicology.biomedcentral.com/articles/10.1186/1743-8977-6-8 DB - PRIME DP - Unbound Medicine ER -