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Mangrove plant extracts: radical scavenging activity and the battle against food-borne pathogens.
Forsch Komplementmed. 2009 Feb; 16(1):41-8.FK

Abstract

AIMS

The present study was carried out to evaluate the radical scavenging and antibacterial activity of methanolic leaf extracts of mangrove plants. 8 mangrove plants, which are used as folk medicine in various tropical countries, were collected in Pichavaram and Thondi, Tamil Nadu, India.

METHODS

The antioxidant properties of methanolic leaf extracts were assessed under in vitro conditions using different antioxidant tests, including DPPH, nitric oxide, hydrogen peroxide, hydroxyl radical scavenging assay, reducing power, ferrous ion chelating, and lipid peroxidation inhibition assay.

RESULTS AND CONCLUSION

Of the 8 mangrove plants screened, Rhizophora mucronata (100 microg/ml) showed significantly higher (p < 0.05) activities for all antioxidant assays, and its IC50 values were 43.17, 116, 60.06, and 46.76 microg/ml for DPPH, hydrogen peroxide, nitric oxide, and hydroxyl radical scavenging activity, respectively. Butylated hydroxytoluene, ascorbic acid and alpha-tocopherol were used as positive controls. Methanolic extracts of R. mucronata were also found to be effective in protecting plasmid DNA against the strand breakage induced by hydroxyl radicals in a Fenton's reaction mixture. Moreover, the total phenolic content of R. mucronata (720.79 mg/gm of dry leaves) was very high and a strong positive correlation was observed between its phenolic content and its antioxidant activity. Methanolic leaf extracts of mangrove plants exhibited no antibacterial activity against seven food-borne pathogens studied.

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Authors+Show Affiliations

Suganthy N
Department of Biotechnology, Alagappa University, Karaikudi, Tamil Nadu, India.
Kesika P
No affiliation info available
Karutha S
No affiliation info available
Kasi P
No affiliation info available
Devi P
No affiliation info available

MeSH

Anti-Bacterial AgentsAntioxidantsBacteriaDNA Breaks, Single-StrandedFood MicrobiologyFree Radical ScavengersInhibitory Concentration 50Lipid PeroxidationMethanolOxidation-ReductionPhenolsPlant ExtractsPlant LeavesVerbenaceae

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19295229

Citation

Suganthy, Natarajan, et al. "Mangrove Plant Extracts: Radical Scavenging Activity and the Battle Against Food-borne Pathogens." Forschende Komplementarmedizin (2006), vol. 16, no. 1, 2009, pp. 41-8.
Suganthy N, Kesika P, Karutha S, et al. Mangrove plant extracts: radical scavenging activity and the battle against food-borne pathogens. Forsch Komplementmed. 2009;16(1):41-8.
Suganthy, N., Kesika, P., Karutha, S., Kasi, P., & Devi, P. (2009). Mangrove plant extracts: radical scavenging activity and the battle against food-borne pathogens. Forschende Komplementarmedizin (2006), 16(1), 41-8. https://doi.org/10.1159/000209852
Suganthy N, et al. Mangrove Plant Extracts: Radical Scavenging Activity and the Battle Against Food-borne Pathogens. Forsch Komplementmed. 2009;16(1):41-8. PubMed PMID: 19295229.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mangrove plant extracts: radical scavenging activity and the battle against food-borne pathogens. AU - Suganthy,Natarajan, AU - Kesika,Periyanaina, AU - Karutha,Shanmugaiahthevar, AU - Kasi,Pandian, AU - Devi,Pandima, Y1 - 2009/02/06/ PY - 2009/3/20/entrez PY - 2009/3/20/pubmed PY - 2009/10/1/medline SP - 41 EP - 8 JF - Forschende Komplementarmedizin (2006) JO - Forsch Komplementmed VL - 16 IS - 1 N2 - AIMS: The present study was carried out to evaluate the radical scavenging and antibacterial activity of methanolic leaf extracts of mangrove plants. 8 mangrove plants, which are used as folk medicine in various tropical countries, were collected in Pichavaram and Thondi, Tamil Nadu, India. METHODS: The antioxidant properties of methanolic leaf extracts were assessed under in vitro conditions using different antioxidant tests, including DPPH, nitric oxide, hydrogen peroxide, hydroxyl radical scavenging assay, reducing power, ferrous ion chelating, and lipid peroxidation inhibition assay. RESULTS AND CONCLUSION: Of the 8 mangrove plants screened, Rhizophora mucronata (100 microg/ml) showed significantly higher (p < 0.05) activities for all antioxidant assays, and its IC50 values were 43.17, 116, 60.06, and 46.76 microg/ml for DPPH, hydrogen peroxide, nitric oxide, and hydroxyl radical scavenging activity, respectively. Butylated hydroxytoluene, ascorbic acid and alpha-tocopherol were used as positive controls. Methanolic extracts of R. mucronata were also found to be effective in protecting plasmid DNA against the strand breakage induced by hydroxyl radicals in a Fenton's reaction mixture. Moreover, the total phenolic content of R. mucronata (720.79 mg/gm of dry leaves) was very high and a strong positive correlation was observed between its phenolic content and its antioxidant activity. Methanolic leaf extracts of mangrove plants exhibited no antibacterial activity against seven food-borne pathogens studied. SN - 1661-4127 UR - https://www.unboundmedicine.com/medline/citation/19295229/Mangrove_plant_extracts:_radical_scavenging_activity_and_the_battle_against_food_borne_pathogens_ L2 - https://www.karger.com?DOI=10.1159/000209852 DB - PRIME DP - Unbound Medicine ER -