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F-18 FDG PET/CT can help differentiate SAPHO syndrome from suspected metastatic bone disease.
Clin Nucl Med 2009; 34(4):254-7CN

Abstract

A 20-year-old woman underwent magnetic resonance imaging of the spine for back pain, which demonstrated a solitary lesion in the T2 vertebral body suspicious for a metastasis. Subsequent computed tomography and bone scintigraphy identified several further sites of bony involvement but no primary malignancy. The patient was referred for F-18 FDG PET/CT which demonstrated intense FDG activity in the sternoclavicular and sacroiliac joints, in addition to the known thoracic vertebral body involvement suggesting spondyloarthropathy rather than malignant disease. During the course of investigations, the patient developed palmoplantar pustulosis leading to a diagnosis of SAPHO syndrome.

Authors+Show Affiliations

Department of Nuclear Medicine, St James's University Hospital, Leeds, UK. chirag.patel@leedsth.nhs.ukNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

19300064

Citation

Patel, Chirag N., et al. "F-18 FDG PET/CT Can Help Differentiate SAPHO Syndrome From Suspected Metastatic Bone Disease." Clinical Nuclear Medicine, vol. 34, no. 4, 2009, pp. 254-7.
Patel CN, Smith JT, Rankine JJ, et al. F-18 FDG PET/CT can help differentiate SAPHO syndrome from suspected metastatic bone disease. Clin Nucl Med. 2009;34(4):254-7.
Patel, C. N., Smith, J. T., Rankine, J. J., & Scarsbrook, A. F. (2009). F-18 FDG PET/CT can help differentiate SAPHO syndrome from suspected metastatic bone disease. Clinical Nuclear Medicine, 34(4), pp. 254-7. doi:10.1097/RLU.0b013e31819a205c.
Patel CN, et al. F-18 FDG PET/CT Can Help Differentiate SAPHO Syndrome From Suspected Metastatic Bone Disease. Clin Nucl Med. 2009;34(4):254-7. PubMed PMID: 19300064.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - F-18 FDG PET/CT can help differentiate SAPHO syndrome from suspected metastatic bone disease. AU - Patel,Chirag N, AU - Smith,Jonathan T, AU - Rankine,James J, AU - Scarsbrook,Andrew F, PY - 2009/3/21/entrez PY - 2009/3/21/pubmed PY - 2009/8/15/medline SP - 254 EP - 7 JF - Clinical nuclear medicine JO - Clin Nucl Med VL - 34 IS - 4 N2 - A 20-year-old woman underwent magnetic resonance imaging of the spine for back pain, which demonstrated a solitary lesion in the T2 vertebral body suspicious for a metastasis. Subsequent computed tomography and bone scintigraphy identified several further sites of bony involvement but no primary malignancy. The patient was referred for F-18 FDG PET/CT which demonstrated intense FDG activity in the sternoclavicular and sacroiliac joints, in addition to the known thoracic vertebral body involvement suggesting spondyloarthropathy rather than malignant disease. During the course of investigations, the patient developed palmoplantar pustulosis leading to a diagnosis of SAPHO syndrome. SN - 1536-0229 UR - https://www.unboundmedicine.com/medline/citation/19300064/F_18_FDG_PET/CT_can_help_differentiate_SAPHO_syndrome_from_suspected_metastatic_bone_disease_ L2 - http://Insights.ovid.com/pubmed?pmid=19300064 DB - PRIME DP - Unbound Medicine ER -