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Xanthogranuloma in the suprasellar region.
Neurol Med Chir (Tokyo). 2009 Mar; 49(3):124-7.NM

Abstract

A 26-year-old man presented with a xanthogranuloma located exclusively in the suprasellar region manifesting as general fatigue, bitemporal hemianopsia, and polyuria. Endocrinological examination disclosed severe hypopituitarism. Magnetic resonance imaging demonstrated a clearly defined suprasellar mass that was heterogeneously enhanced after gadolinium administration and was markedly hypointense on T(2)-weighted images. The tumor was subtotally removed under a preoperative diagnosis of craniopharyngioma. Histological examination found fibrous tissue with abundant cholesterol clefts, multinucleated giant cells, and hemosiderin deposits, but no epithelial cells. Xanthogranulomas of the sellar region are reported to be predominantly located in the sella turcica, but should be included in the differential diagnosis even in cases of suprasellar mass lesions.

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Authors+Show Affiliations

Sugata S
Department of Neurosurgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan.
Hirano H
No affiliation info available
Yatsushiro K
No affiliation info available
Yunoue S
No affiliation info available
Nakamura K
No affiliation info available
Arita K
No affiliation info available

MeSH

AdultCholesterolCranial Fossa, MiddleCraniopharyngiomaDiagnosis, DifferentialHemianopsiaHumansHypopituitarismMagnetic Resonance ImagingMaleNeurosurgical ProceduresOptic ChiasmPituitary GlandPituitary HormonesSella TurcicaSkull Base NeoplasmsTomography, X-Ray ComputedTreatment OutcomeXanthogranuloma, Juvenile

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19318739

Citation

Sugata, Sei, et al. "Xanthogranuloma in the Suprasellar Region." Neurologia Medico-chirurgica, vol. 49, no. 3, 2009, pp. 124-7.
Sugata S, Hirano H, Yatsushiro K, et al. Xanthogranuloma in the suprasellar region. Neurol Med Chir (Tokyo). 2009;49(3):124-7.
Sugata, S., Hirano, H., Yatsushiro, K., Yunoue, S., Nakamura, K., & Arita, K. (2009). Xanthogranuloma in the suprasellar region. Neurologia Medico-chirurgica, 49(3), 124-7.
Sugata S, et al. Xanthogranuloma in the Suprasellar Region. Neurol Med Chir (Tokyo). 2009;49(3):124-7. PubMed PMID: 19318739.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Xanthogranuloma in the suprasellar region. AU - Sugata,Sei, AU - Hirano,Hirofumi, AU - Yatsushiro,Kazutaka, AU - Yunoue,Shunji, AU - Nakamura,Katsumi, AU - Arita,Kazunori, PY - 2009/3/26/entrez PY - 2009/3/26/pubmed PY - 2009/6/23/medline SP - 124 EP - 7 JF - Neurologia medico-chirurgica JO - Neurol Med Chir (Tokyo) VL - 49 IS - 3 N2 - A 26-year-old man presented with a xanthogranuloma located exclusively in the suprasellar region manifesting as general fatigue, bitemporal hemianopsia, and polyuria. Endocrinological examination disclosed severe hypopituitarism. Magnetic resonance imaging demonstrated a clearly defined suprasellar mass that was heterogeneously enhanced after gadolinium administration and was markedly hypointense on T(2)-weighted images. The tumor was subtotally removed under a preoperative diagnosis of craniopharyngioma. Histological examination found fibrous tissue with abundant cholesterol clefts, multinucleated giant cells, and hemosiderin deposits, but no epithelial cells. Xanthogranulomas of the sellar region are reported to be predominantly located in the sella turcica, but should be included in the differential diagnosis even in cases of suprasellar mass lesions. SN - 1349-8029 UR - https://www.unboundmedicine.com/medline/citation/19318739/Xanthogranuloma_in_the_suprasellar_region_ L2 - http://joi.jlc.jst.go.jp/JST.JSTAGE/nmc/49.124?from=PubMed DB - PRIME DP - Unbound Medicine ER -