Tags

Type your tag names separated by a space and hit enter

Effect of long-term endurance and strength training on metabolic control and arterial elasticity in patients with type 2 diabetes mellitus.
Am J Cardiol. 2009 Apr 01; 103(7):972-7.AJ

Abstract

Poor glucose control increases the risk of vascular complications and cardiovascular mortality in patients with diabetes mellitus (DM). Our aim was to evaluate the efficacy of a long-term exercise training program on metabolic control and arterial stiffness in patients with type 2 DM. Fifty men with DM (age 52.3 +/- 5.6 years) were randomly assigned to the exercise training (E) or standard treatment for DM (control [C]) group for 24 months. Supervised exercise training included both endurance and muscle strength training 4 times/week. All exercise sessions were controlled by heart rate and intensity. Glycated hemoglobin A1c, insulin, leptin, blood lipids, blood pressure, maximal oxygen consumption in spiroergometry, and muscle strength were measured every 6 months. Arterial stiffness was assessed by measuring pulse wave velocity. Maximal oxygen consumption in spiroergometry (E 31.9 to 34.8 vs C 32.6 to 31.8 ml/kg/min; p = 0.003), muscle strength (sit-up test, E 12.7 to 20.8 vs C 14.6 to 13.1 times; p <0.001), hemoglobin A1c (E 8.2% to 7.6% vs C 8.0% to 8.3%; p = 0.006), and leptin (E 7.4 to 6.7 vs C 7.4 to 7.9 microg/L; p = 0.013) improved significantly in the E group, but no change or worsening in these variables occurred in the C group. Body weight was not different between groups at 2 years. However, pulse wave velocity increased in both groups (E +0.600 vs C +1.300 m/s; p = 0.27). In conclusion, long-term endurance and strength training was effective and resulted in improved metabolic control of DM compared with standard treatment. Despite significant cardiovascular risk reduction, conduit arterial elasticity did not improve.

Authors+Show Affiliations

Clinical Physiology and Nuclear Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland. antti.loimaala@epshp.fiNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19327425

Citation

Loimaala, Antti, et al. "Effect of Long-term Endurance and Strength Training On Metabolic Control and Arterial Elasticity in Patients With Type 2 Diabetes Mellitus." The American Journal of Cardiology, vol. 103, no. 7, 2009, pp. 972-7.
Loimaala A, Groundstroem K, Rinne M, et al. Effect of long-term endurance and strength training on metabolic control and arterial elasticity in patients with type 2 diabetes mellitus. Am J Cardiol. 2009;103(7):972-7.
Loimaala, A., Groundstroem, K., Rinne, M., Nenonen, A., Huhtala, H., Parkkari, J., & Vuori, I. (2009). Effect of long-term endurance and strength training on metabolic control and arterial elasticity in patients with type 2 diabetes mellitus. The American Journal of Cardiology, 103(7), 972-7. https://doi.org/10.1016/j.amjcard.2008.12.026
Loimaala A, et al. Effect of Long-term Endurance and Strength Training On Metabolic Control and Arterial Elasticity in Patients With Type 2 Diabetes Mellitus. Am J Cardiol. 2009 Apr 1;103(7):972-7. PubMed PMID: 19327425.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of long-term endurance and strength training on metabolic control and arterial elasticity in patients with type 2 diabetes mellitus. AU - Loimaala,Antti, AU - Groundstroem,Kaj, AU - Rinne,Marjo, AU - Nenonen,Arja, AU - Huhtala,Heini, AU - Parkkari,Jari, AU - Vuori,Ilkka, PY - 2008/08/08/received PY - 2008/12/01/revised PY - 2008/12/01/accepted PY - 2009/3/31/entrez PY - 2009/3/31/pubmed PY - 2009/4/15/medline SP - 972 EP - 7 JF - The American journal of cardiology JO - Am J Cardiol VL - 103 IS - 7 N2 - Poor glucose control increases the risk of vascular complications and cardiovascular mortality in patients with diabetes mellitus (DM). Our aim was to evaluate the efficacy of a long-term exercise training program on metabolic control and arterial stiffness in patients with type 2 DM. Fifty men with DM (age 52.3 +/- 5.6 years) were randomly assigned to the exercise training (E) or standard treatment for DM (control [C]) group for 24 months. Supervised exercise training included both endurance and muscle strength training 4 times/week. All exercise sessions were controlled by heart rate and intensity. Glycated hemoglobin A1c, insulin, leptin, blood lipids, blood pressure, maximal oxygen consumption in spiroergometry, and muscle strength were measured every 6 months. Arterial stiffness was assessed by measuring pulse wave velocity. Maximal oxygen consumption in spiroergometry (E 31.9 to 34.8 vs C 32.6 to 31.8 ml/kg/min; p = 0.003), muscle strength (sit-up test, E 12.7 to 20.8 vs C 14.6 to 13.1 times; p <0.001), hemoglobin A1c (E 8.2% to 7.6% vs C 8.0% to 8.3%; p = 0.006), and leptin (E 7.4 to 6.7 vs C 7.4 to 7.9 microg/L; p = 0.013) improved significantly in the E group, but no change or worsening in these variables occurred in the C group. Body weight was not different between groups at 2 years. However, pulse wave velocity increased in both groups (E +0.600 vs C +1.300 m/s; p = 0.27). In conclusion, long-term endurance and strength training was effective and resulted in improved metabolic control of DM compared with standard treatment. Despite significant cardiovascular risk reduction, conduit arterial elasticity did not improve. SN - 1879-1913 UR - https://www.unboundmedicine.com/medline/citation/19327425/Effect_of_long_term_endurance_and_strength_training_on_metabolic_control_and_arterial_elasticity_in_patients_with_type_2_diabetes_mellitus_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9149(08)02177-2 DB - PRIME DP - Unbound Medicine ER -