Tags

Type your tag names separated by a space and hit enter

Exposure to breast milk in infancy and risk of breast cancer.
Cancer Causes Control 2009; 20(7):1083-90CC

Abstract

Early life exposures, such as being breastfed in infancy, may influence the risk of breast cancer in adulthood. We evaluated the risk of breast cancer in relation to ever having been breastfed in infancy among 9,442 women who participated in a population-based, case-control study. Cases were identified through cancer registries in three states (Massachusetts, New Hampshire, and Wisconsin); controls were identified through statewide drivers' license lists or medicare lists. Data on known and suspected risk factors were obtained through telephone interview. We used unconditional logistic regression to assess the relation of breast cancer with ever having been breastfed and with breastfeeding duration (available for only 19% of breastfed women) in premenopausal women (1,986 cases and 1,760 controls) and postmenopausal women (2,600 cases and 2,493 controls). We found no evidence that ever having been breastfed in infancy was associated with breast cancer risk in either premenopausal women (odds ratio [OR] = 0.96; 95% confidence interval [CI] = 0.83-1.10) or postmenopausal women (OR = 0.98; 95% CI = 0.87-1.10). The association did not differ according to breast cancer stage, mother's history of breast cancer, or any other reproductive factor assessed. Likewise, we found no association between breastfeeding duration and risk of breast cancer. Our results did not support the hypothesis that exposure to breast milk in infancy influences the risk of adult breast cancer.

Authors+Show Affiliations

Slone Epidemiology Center, Boston University, Boston, MA 02215, USA. lwise@slone.bu.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

19330531

Citation

Wise, Lauren A., et al. "Exposure to Breast Milk in Infancy and Risk of Breast Cancer." Cancer Causes & Control : CCC, vol. 20, no. 7, 2009, pp. 1083-90.
Wise LA, Titus-Ernstoff L, Newcomb PA, et al. Exposure to breast milk in infancy and risk of breast cancer. Cancer Causes Control. 2009;20(7):1083-90.
Wise, L. A., Titus-Ernstoff, L., Newcomb, P. A., Trentham-Dietz, A., Trichopoulos, D., Hampton, J. M., & Egan, K. M. (2009). Exposure to breast milk in infancy and risk of breast cancer. Cancer Causes & Control : CCC, 20(7), pp. 1083-90. doi:10.1007/s10552-009-9332-0.
Wise LA, et al. Exposure to Breast Milk in Infancy and Risk of Breast Cancer. Cancer Causes Control. 2009;20(7):1083-90. PubMed PMID: 19330531.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Exposure to breast milk in infancy and risk of breast cancer. AU - Wise,Lauren A, AU - Titus-Ernstoff,Linda, AU - Newcomb,Polly A, AU - Trentham-Dietz,Amy, AU - Trichopoulos,Dimitrios, AU - Hampton,John M, AU - Egan,Kathleen M, Y1 - 2009/03/29/ PY - 2008/10/24/received PY - 2009/03/10/accepted PY - 2009/3/31/entrez PY - 2009/3/31/pubmed PY - 2009/8/22/medline SP - 1083 EP - 90 JF - Cancer causes & control : CCC JO - Cancer Causes Control VL - 20 IS - 7 N2 - Early life exposures, such as being breastfed in infancy, may influence the risk of breast cancer in adulthood. We evaluated the risk of breast cancer in relation to ever having been breastfed in infancy among 9,442 women who participated in a population-based, case-control study. Cases were identified through cancer registries in three states (Massachusetts, New Hampshire, and Wisconsin); controls were identified through statewide drivers' license lists or medicare lists. Data on known and suspected risk factors were obtained through telephone interview. We used unconditional logistic regression to assess the relation of breast cancer with ever having been breastfed and with breastfeeding duration (available for only 19% of breastfed women) in premenopausal women (1,986 cases and 1,760 controls) and postmenopausal women (2,600 cases and 2,493 controls). We found no evidence that ever having been breastfed in infancy was associated with breast cancer risk in either premenopausal women (odds ratio [OR] = 0.96; 95% confidence interval [CI] = 0.83-1.10) or postmenopausal women (OR = 0.98; 95% CI = 0.87-1.10). The association did not differ according to breast cancer stage, mother's history of breast cancer, or any other reproductive factor assessed. Likewise, we found no association between breastfeeding duration and risk of breast cancer. Our results did not support the hypothesis that exposure to breast milk in infancy influences the risk of adult breast cancer. SN - 1573-7225 UR - https://www.unboundmedicine.com/medline/citation/19330531/Exposure_to_breast_milk_in_infancy_and_risk_of_breast_cancer_ L2 - https://doi.org/10.1007/s10552-009-9332-0 DB - PRIME DP - Unbound Medicine ER -