Tags

Type your tag names separated by a space and hit enter

A new chalcone glycoside, a new tetrahydrofuranoid lignan, and antioxidative constituents from the stems and leaves of Viburnum propinquum.
Planta Med. 2009 Sep; 75(11):1262-5.PM

Abstract

A new chalcone glycoside (2) and a new tetrahydrofuranoid lignan (3), along with 12 known compounds, were isolated from the stems and leaves of Viburnum propinquum Hemsl. The structures of all isolated compounds were deduced using spectroscopic and chemical methods. Antioxidative activities of most phenolic compounds were evaluated. Compounds 1 (3,4,2',4'-tetrahydroxy- TRANS-chalcone), 2 (3,4,2',4'-tetrahydroxy- TRANS-chalcone-2'- O- beta- D-glucoside), 12 (quercetin), 13 ((+)-dihydroquercetin), and 14 (eriodictyol) showed antioxidative capacities in the DPPH and hydroxyl free-radical assays, with IC (50) values of 3.80-6.12 microg/mL, and 9.24-11.87 microg/mL, respectively. Compounds 1, 2, 12, 13, and 14 also exhibited inhibitory activities against lipid peroxidation in rat liver homogenate, with an inhibitory rate of 10.8-39.9 % at 20 microg/mL, 38.8-57.2 % at 100 microg/mL, and 44.2-72.4 % at 200 microg/mL, respectively.

Links

Publisher Full Text

Authors+Show Affiliations

Wang XY
School of Pharmacy, Shanghai Jiao Tong University, Shanghai, P. R. China.
Shi HM
No affiliation info available
Zhang L
No affiliation info available
Li XB
No affiliation info available

MeSH

AnimalsAntioxidantsChalconesGlycosidesLignansLipid PeroxidationPlant LeavesPlant StemsRatsViburnum

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19330766

Citation

Wang, Xiao-Yu, et al. "A New Chalcone Glycoside, a New Tetrahydrofuranoid Lignan, and Antioxidative Constituents From the Stems and Leaves of Viburnum Propinquum." Planta Medica, vol. 75, no. 11, 2009, pp. 1262-5.
Wang XY, Shi HM, Zhang L, et al. A new chalcone glycoside, a new tetrahydrofuranoid lignan, and antioxidative constituents from the stems and leaves of Viburnum propinquum. Planta Med. 2009;75(11):1262-5.
Wang, X. Y., Shi, H. M., Zhang, L., & Li, X. B. (2009). A new chalcone glycoside, a new tetrahydrofuranoid lignan, and antioxidative constituents from the stems and leaves of Viburnum propinquum. Planta Medica, 75(11), 1262-5. https://doi.org/10.1055/s-0029-1185523
Wang XY, et al. A New Chalcone Glycoside, a New Tetrahydrofuranoid Lignan, and Antioxidative Constituents From the Stems and Leaves of Viburnum Propinquum. Planta Med. 2009;75(11):1262-5. PubMed PMID: 19330766.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A new chalcone glycoside, a new tetrahydrofuranoid lignan, and antioxidative constituents from the stems and leaves of Viburnum propinquum. AU - Wang,Xiao-Yu, AU - Shi,Hai-Ming, AU - Zhang,Li, AU - Li,Xiao-Bo, Y1 - 2009/03/27/ PY - 2009/3/31/entrez PY - 2009/3/31/pubmed PY - 2009/12/16/medline SP - 1262 EP - 5 JF - Planta medica JO - Planta Med VL - 75 IS - 11 N2 - A new chalcone glycoside (2) and a new tetrahydrofuranoid lignan (3), along with 12 known compounds, were isolated from the stems and leaves of Viburnum propinquum Hemsl. The structures of all isolated compounds were deduced using spectroscopic and chemical methods. Antioxidative activities of most phenolic compounds were evaluated. Compounds 1 (3,4,2',4'-tetrahydroxy- TRANS-chalcone), 2 (3,4,2',4'-tetrahydroxy- TRANS-chalcone-2'- O- beta- D-glucoside), 12 (quercetin), 13 ((+)-dihydroquercetin), and 14 (eriodictyol) showed antioxidative capacities in the DPPH and hydroxyl free-radical assays, with IC (50) values of 3.80-6.12 microg/mL, and 9.24-11.87 microg/mL, respectively. Compounds 1, 2, 12, 13, and 14 also exhibited inhibitory activities against lipid peroxidation in rat liver homogenate, with an inhibitory rate of 10.8-39.9 % at 20 microg/mL, 38.8-57.2 % at 100 microg/mL, and 44.2-72.4 % at 200 microg/mL, respectively. SN - 1439-0221 UR - https://www.unboundmedicine.com/medline/citation/19330766/A_new_chalcone_glycoside_a_new_tetrahydrofuranoid_lignan_and_antioxidative_constituents_from_the_stems_and_leaves_of_Viburnum_propinquum_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-0029-1185523 DB - PRIME DP - Unbound Medicine ER -