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Gastrointestinal hemorrhage as the first manifestation of metastatic extragonadal choriocarcinoma.
Intern Med. 2009; 48(7):551-4.IM

Abstract

Although germ cell tumors are the most common malignancy in young men, extragonadal germ cell tumors are rare. Gastric metastasis presenting initially as upper gastrointestinal hemorrhage is also exceedingly rare. A 27-year-old man presented at our hospital with tarry stool. Gastric fiberscopy images revealed a bleeding gastric polypoid lesion in the anterior wall of the gastric body, from which a biopsy specimen was obtained. Histopathological analysis of the biopsy showed syncytiotrophoblast-like cells with multiple, large nuclei, consistent with choriocarcinoma. Based on these results, our diagnosis was extragonadal retroperitoneal germ cell tumor with gastric metastasis.

Authors+Show Affiliations

Department of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan. tomoyosi@juntendo.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

19336957

Citation

Shibuya, Tomoyoshi, et al. "Gastrointestinal Hemorrhage as the First Manifestation of Metastatic Extragonadal Choriocarcinoma." Internal Medicine (Tokyo, Japan), vol. 48, no. 7, 2009, pp. 551-4.
Shibuya T, Osada T, Kodani T, et al. Gastrointestinal hemorrhage as the first manifestation of metastatic extragonadal choriocarcinoma. Intern Med. 2009;48(7):551-4.
Shibuya, T., Osada, T., Kodani, T., Hojo, M., Saito, H., Ueyama, H., Kato, J., Nagahara, A., Otaka, M., Ogihara, T., Nagao, K., Fujime, M., & Watanabe, S. (2009). Gastrointestinal hemorrhage as the first manifestation of metastatic extragonadal choriocarcinoma. Internal Medicine (Tokyo, Japan), 48(7), 551-4.
Shibuya T, et al. Gastrointestinal Hemorrhage as the First Manifestation of Metastatic Extragonadal Choriocarcinoma. Intern Med. 2009;48(7):551-4. PubMed PMID: 19336957.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gastrointestinal hemorrhage as the first manifestation of metastatic extragonadal choriocarcinoma. AU - Shibuya,Tomoyoshi, AU - Osada,Taro, AU - Kodani,Tomohiro, AU - Hojo,Mariko, AU - Saito,Hiroaki, AU - Ueyama,Hiroya, AU - Kato,Junko, AU - Nagahara,Akihito, AU - Otaka,Michiro, AU - Ogihara,Tatsuo, AU - Nagao,Keiji, AU - Fujime,Makoto, AU - Watanabe,Sumio, Y1 - 2009/04/01/ PY - 2009/4/2/entrez PY - 2009/4/2/pubmed PY - 2009/7/31/medline SP - 551 EP - 4 JF - Internal medicine (Tokyo, Japan) JO - Intern. Med. VL - 48 IS - 7 N2 - Although germ cell tumors are the most common malignancy in young men, extragonadal germ cell tumors are rare. Gastric metastasis presenting initially as upper gastrointestinal hemorrhage is also exceedingly rare. A 27-year-old man presented at our hospital with tarry stool. Gastric fiberscopy images revealed a bleeding gastric polypoid lesion in the anterior wall of the gastric body, from which a biopsy specimen was obtained. Histopathological analysis of the biopsy showed syncytiotrophoblast-like cells with multiple, large nuclei, consistent with choriocarcinoma. Based on these results, our diagnosis was extragonadal retroperitoneal germ cell tumor with gastric metastasis. SN - 1349-7235 UR - https://www.unboundmedicine.com/medline/citation/19336957/Gastrointestinal_hemorrhage_as_the_first_manifestation_of_metastatic_extragonadal_choriocarcinoma_ L2 - https://joi.jlc.jst.go.jp/JST.JSTAGE/internalmedicine/48.1867?from=PubMed DB - PRIME DP - Unbound Medicine ER -