Tags

Type your tag names separated by a space and hit enter

Prevalence and risk factors for overlaps between gastroesophageal reflux disease, dyspepsia, and irritable bowel syndrome: a population-based study.
Digestion. 2009; 79(3):196-201.D

Abstract

BACKGROUND/AIMS

People may have symptoms of multiple disorders at the same time. We aimed to determine prevalence and risk factors for overlaps between gastroesophageal reflux disease (GERD), dyspepsia and irritable bowel syndrome (IBS) in a Korean population.

METHODS

A cross-sectional survey was performed on 1,688 randomly selected Korean subjects. Data on 1,443 subjects could be analyzed. Dyspepsia and IBS were diagnosed using modified Rome II criteria.

RESULTS

The prevalences of GERD, dyspepsia and IBS were 8.5, 9.5 and 9.6%. Overlaps between GERD and dyspepsia, GERD and IBS, and dyspepsia and IBS were observed in 2.3 (95% CI 1.4-3.0), 2.0 (95% CI 1.2-2.6%) and 1.3% (95% CI 0.6-1.8%) of the population. 27 and 24% of GERD subjects suffered from dyspepsia and IBS. 24 and 14% of dyspeptic subjects had GERD and IBS. 21 and 14% of IBS subjects had GERD and dyspepsia. Anxiety was significantly associated with GERD overlap (OR 2.73, 95% CI 1.13-6.57), dyspepsia overlap (OR 3.19, 95% CI 1.33-7.63) and IBS overlap (OR 4.92, 95% CI 2.04-11.84), compared with GERD alone, dyspepsia alone and IBS alone.

CONCLUSIONS

Overlaps between GERD, dyspepsia, and IBS are common in the general population. These overlaps occur predominantly in individuals with anxiety.

Authors+Show Affiliations

Department of Preventive Medicine and Public Health, Ajou University School of Medicine, Suwon, South Korea.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19342860

Citation

Lee, Soon Young, et al. "Prevalence and Risk Factors for Overlaps Between Gastroesophageal Reflux Disease, Dyspepsia, and Irritable Bowel Syndrome: a Population-based Study." Digestion, vol. 79, no. 3, 2009, pp. 196-201.
Lee SY, Lee KJ, Kim SJ, et al. Prevalence and risk factors for overlaps between gastroesophageal reflux disease, dyspepsia, and irritable bowel syndrome: a population-based study. Digestion. 2009;79(3):196-201.
Lee, S. Y., Lee, K. J., Kim, S. J., & Cho, S. W. (2009). Prevalence and risk factors for overlaps between gastroesophageal reflux disease, dyspepsia, and irritable bowel syndrome: a population-based study. Digestion, 79(3), 196-201. https://doi.org/10.1159/000211715
Lee SY, et al. Prevalence and Risk Factors for Overlaps Between Gastroesophageal Reflux Disease, Dyspepsia, and Irritable Bowel Syndrome: a Population-based Study. Digestion. 2009;79(3):196-201. PubMed PMID: 19342860.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence and risk factors for overlaps between gastroesophageal reflux disease, dyspepsia, and irritable bowel syndrome: a population-based study. AU - Lee,Soon Young, AU - Lee,Kwang Jae, AU - Kim,Soo Jeong, AU - Cho,Sung Won, Y1 - 2009/04/03/ PY - 2009/01/12/received PY - 2009/02/25/accepted PY - 2009/4/4/entrez PY - 2009/4/4/pubmed PY - 2009/8/7/medline SP - 196 EP - 201 JF - Digestion JO - Digestion VL - 79 IS - 3 N2 - BACKGROUND/AIMS: People may have symptoms of multiple disorders at the same time. We aimed to determine prevalence and risk factors for overlaps between gastroesophageal reflux disease (GERD), dyspepsia and irritable bowel syndrome (IBS) in a Korean population. METHODS: A cross-sectional survey was performed on 1,688 randomly selected Korean subjects. Data on 1,443 subjects could be analyzed. Dyspepsia and IBS were diagnosed using modified Rome II criteria. RESULTS: The prevalences of GERD, dyspepsia and IBS were 8.5, 9.5 and 9.6%. Overlaps between GERD and dyspepsia, GERD and IBS, and dyspepsia and IBS were observed in 2.3 (95% CI 1.4-3.0), 2.0 (95% CI 1.2-2.6%) and 1.3% (95% CI 0.6-1.8%) of the population. 27 and 24% of GERD subjects suffered from dyspepsia and IBS. 24 and 14% of dyspeptic subjects had GERD and IBS. 21 and 14% of IBS subjects had GERD and dyspepsia. Anxiety was significantly associated with GERD overlap (OR 2.73, 95% CI 1.13-6.57), dyspepsia overlap (OR 3.19, 95% CI 1.33-7.63) and IBS overlap (OR 4.92, 95% CI 2.04-11.84), compared with GERD alone, dyspepsia alone and IBS alone. CONCLUSIONS: Overlaps between GERD, dyspepsia, and IBS are common in the general population. These overlaps occur predominantly in individuals with anxiety. SN - 1421-9867 UR - https://www.unboundmedicine.com/medline/citation/19342860/Prevalence_and_risk_factors_for_overlaps_between_gastroesophageal_reflux_disease_dyspepsia_and_irritable_bowel_syndrome:_a_population_based_study_ L2 - https://www.karger.com?DOI=10.1159/000211715 DB - PRIME DP - Unbound Medicine ER -