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DXA-derived abdominal fat mass, waist circumference, and blood lipids in postmenopausal women.
Obesity (Silver Spring). 2009 Aug; 17(8):1635-40.O

Abstract

The purpose of this study was to determine the utility of dual-energy X-ray absorptiometry (DXA)-derived fat mass indices for predicting blood lipid profile in postmenopausal women. A secondary purpose was to determine whether waist circumference is comparable with DXA-derived measurements in predicting blood lipid profile. Subjects were 423 postmenopausal women (age 58.1 +/- 6.3 years). Fat mass was assessed at abdomen, trunk, and total body using DXA. Anthropometric measurements included BMI and waist circumference. Blood samples were analyzed for total cholesterol (TC), triglyceride (TAG), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and cholesterol/HDL ratio. Of the DXA-derived measures, abdominal-fat mass was the best predictor of blood lipid profiles. DXA-derived abdominal fat mass and waist girth explained 20 and 16.5% of variation in TC/HDL ratio, respectively, in univariate analysis, with no difference between the slopes of the regression coefficients. Eighty-four percent of subjects were common to the top quartiles of waist circumference and abdominal fat mass, and blood lipid profiles generally worsened across increasing quartiles. DXA-derived abdominal fat mass and waist circumference are of equivalent utility for predicting alterations in blood lipids. Waist circumference is, therefore, ideal as an inexpensive means in primary health-care services for predicting risk of cardiovascular diseases in postmenopausal women.

Authors+Show Affiliations

College of Pharmacy and Nutrition, School of Public Health, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19343013

Citation

Vatanparast, Hassanali, et al. "DXA-derived Abdominal Fat Mass, Waist Circumference, and Blood Lipids in Postmenopausal Women." Obesity (Silver Spring, Md.), vol. 17, no. 8, 2009, pp. 1635-40.
Vatanparast H, Chilibeck PD, Cornish SM, et al. DXA-derived abdominal fat mass, waist circumference, and blood lipids in postmenopausal women. Obesity (Silver Spring). 2009;17(8):1635-40.
Vatanparast, H., Chilibeck, P. D., Cornish, S. M., Little, J. P., Paus-Jenssen, L. S., Case, A. M., & Biem, H. J. (2009). DXA-derived abdominal fat mass, waist circumference, and blood lipids in postmenopausal women. Obesity (Silver Spring, Md.), 17(8), 1635-40. https://doi.org/10.1038/oby.2009.80
Vatanparast H, et al. DXA-derived Abdominal Fat Mass, Waist Circumference, and Blood Lipids in Postmenopausal Women. Obesity (Silver Spring). 2009;17(8):1635-40. PubMed PMID: 19343013.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - DXA-derived abdominal fat mass, waist circumference, and blood lipids in postmenopausal women. AU - Vatanparast,Hassanali, AU - Chilibeck,Philip D, AU - Cornish,Stephen M, AU - Little,Jonathan P, AU - Paus-Jenssen,Lisa S, AU - Case,Allison M, AU - Biem,H Jay, Y1 - 2009/04/02/ PY - 2009/4/4/entrez PY - 2009/4/4/pubmed PY - 2009/10/9/medline SP - 1635 EP - 40 JF - Obesity (Silver Spring, Md.) JO - Obesity (Silver Spring) VL - 17 IS - 8 N2 - The purpose of this study was to determine the utility of dual-energy X-ray absorptiometry (DXA)-derived fat mass indices for predicting blood lipid profile in postmenopausal women. A secondary purpose was to determine whether waist circumference is comparable with DXA-derived measurements in predicting blood lipid profile. Subjects were 423 postmenopausal women (age 58.1 +/- 6.3 years). Fat mass was assessed at abdomen, trunk, and total body using DXA. Anthropometric measurements included BMI and waist circumference. Blood samples were analyzed for total cholesterol (TC), triglyceride (TAG), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and cholesterol/HDL ratio. Of the DXA-derived measures, abdominal-fat mass was the best predictor of blood lipid profiles. DXA-derived abdominal fat mass and waist girth explained 20 and 16.5% of variation in TC/HDL ratio, respectively, in univariate analysis, with no difference between the slopes of the regression coefficients. Eighty-four percent of subjects were common to the top quartiles of waist circumference and abdominal fat mass, and blood lipid profiles generally worsened across increasing quartiles. DXA-derived abdominal fat mass and waist circumference are of equivalent utility for predicting alterations in blood lipids. Waist circumference is, therefore, ideal as an inexpensive means in primary health-care services for predicting risk of cardiovascular diseases in postmenopausal women. SN - 1930-7381 UR - https://www.unboundmedicine.com/medline/citation/19343013/DXA_derived_abdominal_fat_mass_waist_circumference_and_blood_lipids_in_postmenopausal_women_ L2 - https://doi.org/10.1038/oby.2009.80 DB - PRIME DP - Unbound Medicine ER -