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Identification of Ecl family genes that extend chronological lifespan in fission yeast.
Biosci Biotechnol Biochem. 2009 Apr 23; 73(4):885-9.BB

Abstract

In fission yeast, we identified two genes, named ecl2+ and ecl3+, that are paralogous to ecl1+, which extends the chronological lifespan. Both ecl2+ and ecl3+ extend the chronological lifespan when overexpressed as ecl1+. ecl2+ and ecl3+ encode 84- and 89-amino acid polypeptides respectively that are not annotated in the current database. The Ecl2 protein is localized mainly in the nucleus, as Ecl1. These results suggest that ecl1+, ecl2+, and ecl3+ have overlapping functions in the regulation of chronological lifespan.

Authors+Show Affiliations

Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Chikusa-ku, Nagoya 464-8601, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19352039

Citation

Ohtsuka, Hokuto, et al. "Identification of Ecl Family Genes That Extend Chronological Lifespan in Fission Yeast." Bioscience, Biotechnology, and Biochemistry, vol. 73, no. 4, 2009, pp. 885-9.
Ohtsuka H, Ogawa Y, Mizuno H, et al. Identification of Ecl family genes that extend chronological lifespan in fission yeast. Biosci Biotechnol Biochem. 2009;73(4):885-9.
Ohtsuka, H., Ogawa, Y., Mizuno, H., Mita, S., & Aiba, H. (2009). Identification of Ecl family genes that extend chronological lifespan in fission yeast. Bioscience, Biotechnology, and Biochemistry, 73(4), 885-9.
Ohtsuka H, et al. Identification of Ecl Family Genes That Extend Chronological Lifespan in Fission Yeast. Biosci Biotechnol Biochem. 2009 Apr 23;73(4):885-9. PubMed PMID: 19352039.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Identification of Ecl family genes that extend chronological lifespan in fission yeast. AU - Ohtsuka,Hokuto, AU - Ogawa,Yuki, AU - Mizuno,Hiroyuki, AU - Mita,Satoka, AU - Aiba,Hirofumi, Y1 - 2009/04/07/ PY - 2009/4/9/entrez PY - 2009/4/9/pubmed PY - 2009/6/25/medline SP - 885 EP - 9 JF - Bioscience, biotechnology, and biochemistry JO - Biosci Biotechnol Biochem VL - 73 IS - 4 N2 - In fission yeast, we identified two genes, named ecl2+ and ecl3+, that are paralogous to ecl1+, which extends the chronological lifespan. Both ecl2+ and ecl3+ extend the chronological lifespan when overexpressed as ecl1+. ecl2+ and ecl3+ encode 84- and 89-amino acid polypeptides respectively that are not annotated in the current database. The Ecl2 protein is localized mainly in the nucleus, as Ecl1. These results suggest that ecl1+, ecl2+, and ecl3+ have overlapping functions in the regulation of chronological lifespan. SN - 1347-6947 UR - https://www.unboundmedicine.com/medline/citation/19352039/Identification_of_Ecl_family_genes_that_extend_chronological_lifespan_in_fission_yeast_ L2 - https://joi.jlc.jst.go.jp/JST.JSTAGE/bbb/80804?lang=en&from=PubMed DB - PRIME DP - Unbound Medicine ER -