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Sleep disturbances in Malaysian patients with Parkinson's disease using polysomnography and PDSS.
Parkinsonism Relat Disord. 2009 Nov; 15(9):670-4.PR

Abstract

BACKGROUND

Sleep disturbances such as sleep fragmentation, sleep disordered breathing (SDB), periodic limb movements (PLM), excessive daytime somnolence (EDS) and insomnia are prevalent in Parkinson's disease (PD). However, studies in the Asian population are limited.

METHODS

This was a cross-sectional study involving 46 Malaysians with PD using polysomnography (PSG) and standardized translated Parkinson's disease sleep scale (PDSS). Overnight PSG recordings, UPDRS and PDSS scores, and baseline demographic data were obtained.

RESULTS

Data from 44 patients were analysed. Thirty-six patients (81.8%) had PSG-quantified sleep disorders. Twenty-three (52.3%) had sleep fragmentation, 24 (54.6%) had SDB and 14 (32%) had PLM. EDS was present in 9.1%. Insomnia was reported by 31.8%. Patients with sleep fragmentation had significantly higher UPDRS scores and lower PDSS insomnia sub-scores. The UPDRS scores correlated negatively with the TST and sleep efficiency. All patients with EDS had SDB (p=0.056). The PDSS insomnia sub-items correlated with sleep fragmentation on PSG.

CONCLUSION

: The prevalence of sleep disorders based on PSG and PDSS in our PD patients was high, the commonest being sleep fragmentation and SDB, while EDS was the least prevalent. Problem specific sub-items of the PDSS were more accurate in predicting the relevant PSG-related changes compared to the PDSS as a whole.

Authors+Show Affiliations

Neurology Unit, Department of Medicine, Universiti Kebangsaan Malaysia Medical Center, Kuala Lumpur, Malaysia. norlinah@ppukm.ukm.myNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19362875

Citation

Norlinah, M I., et al. "Sleep Disturbances in Malaysian Patients With Parkinson's Disease Using Polysomnography and PDSS." Parkinsonism & Related Disorders, vol. 15, no. 9, 2009, pp. 670-4.
Norlinah MI, Afidah KN, Noradina AT, et al. Sleep disturbances in Malaysian patients with Parkinson's disease using polysomnography and PDSS. Parkinsonism Relat Disord. 2009;15(9):670-4.
Norlinah, M. I., Afidah, K. N., Noradina, A. T., Shamsul, A. S., Hamidon, B. B., Sahathevan, R., & Raymond, A. A. (2009). Sleep disturbances in Malaysian patients with Parkinson's disease using polysomnography and PDSS. Parkinsonism & Related Disorders, 15(9), 670-4. https://doi.org/10.1016/j.parkreldis.2009.02.012
Norlinah MI, et al. Sleep Disturbances in Malaysian Patients With Parkinson's Disease Using Polysomnography and PDSS. Parkinsonism Relat Disord. 2009;15(9):670-4. PubMed PMID: 19362875.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sleep disturbances in Malaysian patients with Parkinson's disease using polysomnography and PDSS. AU - Norlinah,M I, AU - Afidah,K Nor, AU - Noradina,A T, AU - Shamsul,A S, AU - Hamidon,B B, AU - Sahathevan,R, AU - Raymond,A A, Y1 - 2009/04/11/ PY - 2008/10/10/received PY - 2009/02/13/revised PY - 2009/02/26/accepted PY - 2009/4/14/entrez PY - 2009/4/14/pubmed PY - 2010/1/9/medline SP - 670 EP - 4 JF - Parkinsonism & related disorders JO - Parkinsonism Relat Disord VL - 15 IS - 9 N2 - BACKGROUND: Sleep disturbances such as sleep fragmentation, sleep disordered breathing (SDB), periodic limb movements (PLM), excessive daytime somnolence (EDS) and insomnia are prevalent in Parkinson's disease (PD). However, studies in the Asian population are limited. METHODS: This was a cross-sectional study involving 46 Malaysians with PD using polysomnography (PSG) and standardized translated Parkinson's disease sleep scale (PDSS). Overnight PSG recordings, UPDRS and PDSS scores, and baseline demographic data were obtained. RESULTS: Data from 44 patients were analysed. Thirty-six patients (81.8%) had PSG-quantified sleep disorders. Twenty-three (52.3%) had sleep fragmentation, 24 (54.6%) had SDB and 14 (32%) had PLM. EDS was present in 9.1%. Insomnia was reported by 31.8%. Patients with sleep fragmentation had significantly higher UPDRS scores and lower PDSS insomnia sub-scores. The UPDRS scores correlated negatively with the TST and sleep efficiency. All patients with EDS had SDB (p=0.056). The PDSS insomnia sub-items correlated with sleep fragmentation on PSG. CONCLUSION: : The prevalence of sleep disorders based on PSG and PDSS in our PD patients was high, the commonest being sleep fragmentation and SDB, while EDS was the least prevalent. Problem specific sub-items of the PDSS were more accurate in predicting the relevant PSG-related changes compared to the PDSS as a whole. SN - 1873-5126 UR - https://www.unboundmedicine.com/medline/citation/19362875/Sleep_disturbances_in_Malaysian_patients_with_Parkinson's_disease_using_polysomnography_and_PDSS_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1353-8020(09)00061-3 DB - PRIME DP - Unbound Medicine ER -