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Fatty liver in adolescents on the U.S.-Mexico border.
J Am Acad Nurse Pract. 2009 Apr; 21(4):225-30.JA

Abstract

PURPOSE

To describe the physical and metabolic characteristics of children diagnosed with fatty liver disease in a gastroenterology clinic in El Paso, Texas.

DATA SOURCES

A retrospective chart review of 31 patients aged 8-18 diagnosed with fatty liver was conducted.

CONCLUSIONS

These children were diagnosed with fatty liver by elevated alanine aminotransferase (ALT) levels (mean ALT levels 126 +/- 08 U/L) and increased hepatic echogenicity measured via ultrasound. The majority of children were adolescents (12-17 years of age) and Mexican American. All subjects were overweight (body mass index [BMI] > or = 95th percentile) based on Centers for Disease Control and Prevention standards. In a subset of children for whom results from laboratory test were available, we found 40% had high triglycerides (> or = 150 mg/dL), 53% had low high-density lipoprotein cholesterol (< or = 35 mg/dL), and 17% had prediabetes (fasting glucose > or = 100 mg/dL). The clinical and laboratory findings in this patient population with fatty liver are consistent with a diagnosis of nonalcoholic fatty liver disease (NAFLD).

IMPLICATIONS FOR PRACTICE

Despite the increasing trend in overweight among children and adolescents, data suggest low rates of diagnosis and management of overweight and related comorbidities by healthcare providers. Overweight has been associated with fatty liver disease in the pediatric population and includes other comorbidities such insulin resistance and features of metabolic syndrome. Screening for overweight in children should constitute the first step in identifying children at risk for NAFLD. Nurse practitioners should include in the evaluation of pediatric patients calculation of BMI and waist circumference for age and screening for other overweight-related comorbidities.

Authors+Show Affiliations

School of Nursing, University of Texas at El Paso, El Paso, Texas79902, USA. dbsharp@utep.eduNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19366381

Citation

Sharp, Dayle Boynton, et al. "Fatty Liver in Adolescents On the U.S.-Mexico Border." Journal of the American Academy of Nurse Practitioners, vol. 21, no. 4, 2009, pp. 225-30.
Sharp DB, Santos LA, Cruz ML. Fatty liver in adolescents on the U.S.-Mexico border. J Am Acad Nurse Pract. 2009;21(4):225-30.
Sharp, D. B., Santos, L. A., & Cruz, M. L. (2009). Fatty liver in adolescents on the U.S.-Mexico border. Journal of the American Academy of Nurse Practitioners, 21(4), 225-30. https://doi.org/10.1111/j.1745-7599.2009.00397.x
Sharp DB, Santos LA, Cruz ML. Fatty Liver in Adolescents On the U.S.-Mexico Border. J Am Acad Nurse Pract. 2009;21(4):225-30. PubMed PMID: 19366381.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fatty liver in adolescents on the U.S.-Mexico border. AU - Sharp,Dayle Boynton, AU - Santos,Luis A, AU - Cruz,Martha L, PY - 2009/4/16/entrez PY - 2009/4/16/pubmed PY - 2009/7/23/medline SP - 225 EP - 30 JF - Journal of the American Academy of Nurse Practitioners JO - J Am Acad Nurse Pract VL - 21 IS - 4 N2 - PURPOSE: To describe the physical and metabolic characteristics of children diagnosed with fatty liver disease in a gastroenterology clinic in El Paso, Texas. DATA SOURCES: A retrospective chart review of 31 patients aged 8-18 diagnosed with fatty liver was conducted. CONCLUSIONS: These children were diagnosed with fatty liver by elevated alanine aminotransferase (ALT) levels (mean ALT levels 126 +/- 08 U/L) and increased hepatic echogenicity measured via ultrasound. The majority of children were adolescents (12-17 years of age) and Mexican American. All subjects were overweight (body mass index [BMI] > or = 95th percentile) based on Centers for Disease Control and Prevention standards. In a subset of children for whom results from laboratory test were available, we found 40% had high triglycerides (> or = 150 mg/dL), 53% had low high-density lipoprotein cholesterol (< or = 35 mg/dL), and 17% had prediabetes (fasting glucose > or = 100 mg/dL). The clinical and laboratory findings in this patient population with fatty liver are consistent with a diagnosis of nonalcoholic fatty liver disease (NAFLD). IMPLICATIONS FOR PRACTICE: Despite the increasing trend in overweight among children and adolescents, data suggest low rates of diagnosis and management of overweight and related comorbidities by healthcare providers. Overweight has been associated with fatty liver disease in the pediatric population and includes other comorbidities such insulin resistance and features of metabolic syndrome. Screening for overweight in children should constitute the first step in identifying children at risk for NAFLD. Nurse practitioners should include in the evaluation of pediatric patients calculation of BMI and waist circumference for age and screening for other overweight-related comorbidities. SN - 1745-7599 UR - https://www.unboundmedicine.com/medline/citation/19366381/Fatty_liver_in_adolescents_on_the_U_S__Mexico_border_ L2 - https://doi.org/10.1111/j.1745-7599.2009.00397.x DB - PRIME DP - Unbound Medicine ER -