Tags

Type your tag names separated by a space and hit enter

Nervous system lyme disease: diagnosis and treatment.
Rev Neurol Dis. 2009 Winter; 6(1):4-12.RN

Abstract

Lyme disease, the multisystem infectious disease caused by the tickborne spirochete Borrelia burgdorferi, frequently affects the peripheral and central nervous systems. The earliest indication of Lyme disease infection is usually erythema migrans. This large, typically macular erythema, often with a target-like pattern of concentric pale and red circles, gradually enlarges day by day, potentially reaching many centimeters in diameter. In a significant proportion of infected individuals, an acute disseminated phase leads to seeding elsewhere in the body. Up to 5% of patients develop cardiac involvement. In about 10% to 15% of patients, the nervous system becomes symptomatically involved. Current serologic diagnostic tools are quite useful, and standard treatment regimens are highly effective. Oral antimicrobials have been shown to be effective in European neuroborreliosis and presumably are equally potent in North American patients. Long-term antibiotic treatment does not provide any additional lasting improvement, but it is frequently associated with significant morbidity.

Authors+Show Affiliations

Department of Neurosciences, Atlantic Neuroscience Institute, Summit, NJ, USA.

Pub Type(s)

Historical Article
Journal Article
Review

Language

eng

PubMed ID

19367218

Citation

Halperin, John J.. "Nervous System Lyme Disease: Diagnosis and Treatment." Reviews in Neurological Diseases, vol. 6, no. 1, 2009, pp. 4-12.
Halperin JJ. Nervous system lyme disease: diagnosis and treatment. Rev Neurol Dis. 2009;6(1):4-12.
Halperin, J. J. (2009). Nervous system lyme disease: diagnosis and treatment. Reviews in Neurological Diseases, 6(1), 4-12.
Halperin JJ. Nervous System Lyme Disease: Diagnosis and Treatment. Rev Neurol Dis. 2009;6(1):4-12. PubMed PMID: 19367218.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nervous system lyme disease: diagnosis and treatment. A1 - Halperin,John J, PY - 2009/4/16/entrez PY - 2009/4/16/pubmed PY - 2009/6/10/medline SP - 4 EP - 12 JF - Reviews in neurological diseases JO - Rev Neurol Dis VL - 6 IS - 1 N2 - Lyme disease, the multisystem infectious disease caused by the tickborne spirochete Borrelia burgdorferi, frequently affects the peripheral and central nervous systems. The earliest indication of Lyme disease infection is usually erythema migrans. This large, typically macular erythema, often with a target-like pattern of concentric pale and red circles, gradually enlarges day by day, potentially reaching many centimeters in diameter. In a significant proportion of infected individuals, an acute disseminated phase leads to seeding elsewhere in the body. Up to 5% of patients develop cardiac involvement. In about 10% to 15% of patients, the nervous system becomes symptomatically involved. Current serologic diagnostic tools are quite useful, and standard treatment regimens are highly effective. Oral antimicrobials have been shown to be effective in European neuroborreliosis and presumably are equally potent in North American patients. Long-term antibiotic treatment does not provide any additional lasting improvement, but it is frequently associated with significant morbidity. SN - 1545-2913 UR - https://www.unboundmedicine.com/medline/citation/19367218/Nervous_system_lyme_disease:_diagnosis_and_treatment_ L2 - http://www.diseaseinfosearch.org/result/9677 DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.