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Age-related differences in inhibitory processes during interlimb coordination.
Brain Res. 2009 Mar 25; 1262:38-47.BR

Abstract

The study examined the neurophysiological correlates of age-related changes in the coordination of hand and foot movements. Young and older adults (N=30) performed cyclical isodirectional and non-isodirectional hand-foot movements with contralateral and ipsilateral limb combinations. Motor evoked potentials (MEPs) and silent period durations following transcranial magnetic stimulation (TMS) were measured from the right extensor carpi radialis (ECR) muscle during the interlimb coordination tasks. Older adults demonstrated lower coordination stability than younger adults, particularly when performing non-isodirectional movements with ipsilateral limbs. For all coordination tasks, MEP amplitude was lower in older compared with young participants. Young adults showed significantly longer silent period durations when the coordination pattern involved ipsilateral limbs than during contralateral limb coordination. In contrast, silent period durations did not differ between contralateral and ipsilateral limb coordination in older adults. These results suggest that deterioration in motor performance with advancing age may be associated with a decreased ability to modulate inhibitory function.

Authors+Show Affiliations

Human Motor Control Laboratory, School of Psychology, University of Tasmania, Hobart, Tasmania 7001, Australia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19368842

Citation

Fujiyama, Hakuei, et al. "Age-related Differences in Inhibitory Processes During Interlimb Coordination." Brain Research, vol. 1262, 2009, pp. 38-47.
Fujiyama H, Garry MI, Levin O, et al. Age-related differences in inhibitory processes during interlimb coordination. Brain Res. 2009;1262:38-47.
Fujiyama, H., Garry, M. I., Levin, O., Swinnen, S. P., & Summers, J. J. (2009). Age-related differences in inhibitory processes during interlimb coordination. Brain Research, 1262, 38-47. https://doi.org/10.1016/j.brainres.2009.01.023
Fujiyama H, et al. Age-related Differences in Inhibitory Processes During Interlimb Coordination. Brain Res. 2009 Mar 25;1262:38-47. PubMed PMID: 19368842.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Age-related differences in inhibitory processes during interlimb coordination. AU - Fujiyama,Hakuei, AU - Garry,Mike I, AU - Levin,Oron, AU - Swinnen,Stephan P, AU - Summers,Jeffrey J, Y1 - 2009/02/07/ PY - 2008/06/06/received PY - 2009/01/06/revised PY - 2009/01/14/accepted PY - 2009/4/17/entrez PY - 2009/4/17/pubmed PY - 2009/6/25/medline SP - 38 EP - 47 JF - Brain research JO - Brain Res VL - 1262 N2 - The study examined the neurophysiological correlates of age-related changes in the coordination of hand and foot movements. Young and older adults (N=30) performed cyclical isodirectional and non-isodirectional hand-foot movements with contralateral and ipsilateral limb combinations. Motor evoked potentials (MEPs) and silent period durations following transcranial magnetic stimulation (TMS) were measured from the right extensor carpi radialis (ECR) muscle during the interlimb coordination tasks. Older adults demonstrated lower coordination stability than younger adults, particularly when performing non-isodirectional movements with ipsilateral limbs. For all coordination tasks, MEP amplitude was lower in older compared with young participants. Young adults showed significantly longer silent period durations when the coordination pattern involved ipsilateral limbs than during contralateral limb coordination. In contrast, silent period durations did not differ between contralateral and ipsilateral limb coordination in older adults. These results suggest that deterioration in motor performance with advancing age may be associated with a decreased ability to modulate inhibitory function. SN - 1872-6240 UR - https://www.unboundmedicine.com/medline/citation/19368842/Age_related_differences_in_inhibitory_processes_during_interlimb_coordination_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0006-8993(09)00126-7 DB - PRIME DP - Unbound Medicine ER -