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Difficulties with physical function associated with obesity, sarcopenia, and sarcopenic-obesity in community-dwelling elderly women: the EPIDOS (EPIDemiologie de l'OSteoporose) Study.
Am J Clin Nutr 2009; 89(6):1895-900AJ

Abstract

BACKGROUND

In elders, decreased muscle mass (sarcopenia) and increased fat mass (obesity) may contribute to difficulties with physical function.

OBJECTIVE

The objective was to examine the association of obesity, sarcopenia, and their combination (sarcopenic-obesity) with self-reported difficulties performing physical function in a cohort of community-dwelling elderly women.

DESIGN

We assessed muscle and fat mass by dual-energy X-ray absorptiometry and self-reported difficulties with physical function in 1308 healthy women aged > or =75 y. Sarcopenia was defined as an appendicular skeletal muscle mass < or =2 SD below the mean in a young female reference group. Obesity was defined as a percentage body fat above the 60th percentile. Thirty-six sarcopenic-obese, 90 purely sarcopenic, 435 purely obese, and 747 women with a healthy body composition were studied. Anthropometric measures, health status, lifestyle habits, and self-reported difficulties with 6 different physical functions were obtained.

RESULTS

Compared with women with a healthy body composition and after adjustment for confounders, purely sarcopenic women had no increased odds of having difficulties for all of the physical functions assessed, purely obese women had a 44-79% higher odds of having difficulties with most of the physical functions assessed (P < 0.05), and sarcopenic-obese women had a 2.60 higher odds of having difficulty climbing stairs and a 2.35 higher odds of having difficulty going down stairs (all P < 0.05).

CONCLUSIONS

Sarcopenia is not associated with physical difficulties in the absence of obesity. However, in the presence of obesity, sarcopenia tends to add difficulty for some physical functions.

Authors+Show Affiliations

Service de Médecine Interne et de Gérontologie Clinique, Hôpital La Grave-Casselardit, Toulouse, France. rolland.y@chu-toulouse.frNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19369381

Citation

Rolland, Yves, et al. "Difficulties With Physical Function Associated With Obesity, Sarcopenia, and Sarcopenic-obesity in Community-dwelling Elderly Women: the EPIDOS (EPIDemiologie De l'OSteoporose) Study." The American Journal of Clinical Nutrition, vol. 89, no. 6, 2009, pp. 1895-900.
Rolland Y, Lauwers-Cances V, Cristini C, et al. Difficulties with physical function associated with obesity, sarcopenia, and sarcopenic-obesity in community-dwelling elderly women: the EPIDOS (EPIDemiologie de l'OSteoporose) Study. Am J Clin Nutr. 2009;89(6):1895-900.
Rolland, Y., Lauwers-Cances, V., Cristini, C., Abellan van Kan, G., Janssen, I., Morley, J. E., & Vellas, B. (2009). Difficulties with physical function associated with obesity, sarcopenia, and sarcopenic-obesity in community-dwelling elderly women: the EPIDOS (EPIDemiologie de l'OSteoporose) Study. The American Journal of Clinical Nutrition, 89(6), pp. 1895-900. doi:10.3945/ajcn.2008.26950.
Rolland Y, et al. Difficulties With Physical Function Associated With Obesity, Sarcopenia, and Sarcopenic-obesity in Community-dwelling Elderly Women: the EPIDOS (EPIDemiologie De l'OSteoporose) Study. Am J Clin Nutr. 2009;89(6):1895-900. PubMed PMID: 19369381.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Difficulties with physical function associated with obesity, sarcopenia, and sarcopenic-obesity in community-dwelling elderly women: the EPIDOS (EPIDemiologie de l'OSteoporose) Study. AU - Rolland,Yves, AU - Lauwers-Cances,Valérie, AU - Cristini,Christelle, AU - Abellan van Kan,Gabor, AU - Janssen,Ian, AU - Morley,John E, AU - Vellas,Bruno, Y1 - 2009/04/15/ PY - 2009/4/17/entrez PY - 2009/4/17/pubmed PY - 2009/6/13/medline SP - 1895 EP - 900 JF - The American journal of clinical nutrition JO - Am. J. Clin. Nutr. VL - 89 IS - 6 N2 - BACKGROUND: In elders, decreased muscle mass (sarcopenia) and increased fat mass (obesity) may contribute to difficulties with physical function. OBJECTIVE: The objective was to examine the association of obesity, sarcopenia, and their combination (sarcopenic-obesity) with self-reported difficulties performing physical function in a cohort of community-dwelling elderly women. DESIGN: We assessed muscle and fat mass by dual-energy X-ray absorptiometry and self-reported difficulties with physical function in 1308 healthy women aged > or =75 y. Sarcopenia was defined as an appendicular skeletal muscle mass < or =2 SD below the mean in a young female reference group. Obesity was defined as a percentage body fat above the 60th percentile. Thirty-six sarcopenic-obese, 90 purely sarcopenic, 435 purely obese, and 747 women with a healthy body composition were studied. Anthropometric measures, health status, lifestyle habits, and self-reported difficulties with 6 different physical functions were obtained. RESULTS: Compared with women with a healthy body composition and after adjustment for confounders, purely sarcopenic women had no increased odds of having difficulties for all of the physical functions assessed, purely obese women had a 44-79% higher odds of having difficulties with most of the physical functions assessed (P < 0.05), and sarcopenic-obese women had a 2.60 higher odds of having difficulty climbing stairs and a 2.35 higher odds of having difficulty going down stairs (all P < 0.05). CONCLUSIONS: Sarcopenia is not associated with physical difficulties in the absence of obesity. However, in the presence of obesity, sarcopenia tends to add difficulty for some physical functions. SN - 1938-3207 UR - https://www.unboundmedicine.com/medline/citation/19369381/Difficulties_with_physical_function_associated_with_obesity_sarcopenia_and_sarcopenic_obesity_in_community_dwelling_elderly_women:_the_EPIDOS__EPIDemiologie_de_l'OSteoporose__Study_ L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.3945/ajcn.2008.26950 DB - PRIME DP - Unbound Medicine ER -