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Development of functional gastrointestinal disorders after Giardia lamblia infection.
BMC Gastroenterol. 2009 Apr 21; 9:27.BG

Abstract

BACKGROUND

Functional gastrointestinal disorders (FGID) may occur following acute gastroenteritis. This long-term complication has previously not been described after infection with the non-invasive protozoan Giardia lamblia. This study aims to characterize persistent abdominal symptoms elicited by Giardia infection according to Rome II criteria and symptoms scores.

METHODS

Structured interview and questionnaires 12-30 months after the onset of Giardia infection, and at least 6 months after Giardia eradication, among 82 patients with persisting abdominal symptoms elicited by the Giardia infection. All had been evaluated to exclude other causes.

RESULTS

We found that 66 (80.5%) of the 82 patients had symptoms consistent with irritable bowel syndrome (IBS) and 17 (24.3%) patients had functional dyspepsia (FD) according to Rome II criteria. IBS was sub classified into D-IBS (47.0%), A-IBS (45.5%) and C-IBS (7.6%). Bloating, diarrhoea and abdominal pain were reported to be most severe. Symptoms exacerbation related to specific foods were reported by 45 (57.7%) patients and to physical or mental stress by 34 (44.7%) patients.

CONCLUSION

In the presence of an IBS-subtype pattern consistent with post-infectious IBS (PI-IBS), and in the absence of any other plausible causes, we conclude that acute Giardia infection may elicit functional gastrointestinal diseases with food and stress related symptoms similar to FGID patients in general.

Authors+Show Affiliations

Institute of Medicine, University of Bergen, Bergen, Norway. mfakh@ikb.uib.noNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19383162

Citation

Hanevik, Kurt, et al. "Development of Functional Gastrointestinal Disorders After Giardia Lamblia Infection." BMC Gastroenterology, vol. 9, 2009, p. 27.
Hanevik K, Dizdar V, Langeland N, et al. Development of functional gastrointestinal disorders after Giardia lamblia infection. BMC Gastroenterol. 2009;9:27.
Hanevik, K., Dizdar, V., Langeland, N., & Hausken, T. (2009). Development of functional gastrointestinal disorders after Giardia lamblia infection. BMC Gastroenterology, 9, 27. https://doi.org/10.1186/1471-230X-9-27
Hanevik K, et al. Development of Functional Gastrointestinal Disorders After Giardia Lamblia Infection. BMC Gastroenterol. 2009 Apr 21;9:27. PubMed PMID: 19383162.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Development of functional gastrointestinal disorders after Giardia lamblia infection. AU - Hanevik,Kurt, AU - Dizdar,Vernesa, AU - Langeland,Nina, AU - Hausken,Trygve, Y1 - 2009/04/21/ PY - 2008/10/20/received PY - 2009/04/21/accepted PY - 2009/4/23/entrez PY - 2009/4/23/pubmed PY - 2009/6/24/medline SP - 27 EP - 27 JF - BMC gastroenterology JO - BMC Gastroenterol VL - 9 N2 - BACKGROUND: Functional gastrointestinal disorders (FGID) may occur following acute gastroenteritis. This long-term complication has previously not been described after infection with the non-invasive protozoan Giardia lamblia. This study aims to characterize persistent abdominal symptoms elicited by Giardia infection according to Rome II criteria and symptoms scores. METHODS: Structured interview and questionnaires 12-30 months after the onset of Giardia infection, and at least 6 months after Giardia eradication, among 82 patients with persisting abdominal symptoms elicited by the Giardia infection. All had been evaluated to exclude other causes. RESULTS: We found that 66 (80.5%) of the 82 patients had symptoms consistent with irritable bowel syndrome (IBS) and 17 (24.3%) patients had functional dyspepsia (FD) according to Rome II criteria. IBS was sub classified into D-IBS (47.0%), A-IBS (45.5%) and C-IBS (7.6%). Bloating, diarrhoea and abdominal pain were reported to be most severe. Symptoms exacerbation related to specific foods were reported by 45 (57.7%) patients and to physical or mental stress by 34 (44.7%) patients. CONCLUSION: In the presence of an IBS-subtype pattern consistent with post-infectious IBS (PI-IBS), and in the absence of any other plausible causes, we conclude that acute Giardia infection may elicit functional gastrointestinal diseases with food and stress related symptoms similar to FGID patients in general. SN - 1471-230X UR - https://www.unboundmedicine.com/medline/citation/19383162/full_citation L2 - https://bmcgastroenterol.biomedcentral.com/articles/10.1186/1471-230X-9-27 DB - PRIME DP - Unbound Medicine ER -