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Chemical composition, antibacterial and antifungal activity of the essential oil of Thymbra spicata L. from Turkey.
Nat Prod Res. 2009; 23(6):572-9.NP

Abstract

The composition of the essential oil from aerial parts of Thymbra spicata L. from Turkey was analysed by GC-MS and its in vitro antimicrobial activity was examined. GC-MS analysis of the essential oil resulted in the identification of twenty-three constituents, representing 97.04% of the oil. The major compounds detected in the essential oil were carvacrol (60.39%), gamma-terpinene (12.95%), and p-cymene (9.61%). The in vitro efficacy of the essential oil against 21 bacteria and seven Candida species was examined using disc diffusion and minimum inhibitory concentration (MIC) methods. The essential oil demonstrated strong anti-microbial activity in a wide spectrum against most microorganisms, particularly the yeasts tested. This is the first report on the anticandidal properties of the essential oil of T. spicata. In conclusion, this study confirms that T. spicata essential oil could be considered as a natural antimicrobial source.

Authors+Show Affiliations

Department of Microbiology, Faculty of Medicine, Cumhuriyet University, 58140 Sivas, Turkey. unlum@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19384734

Citation

Unlü, Mehmet, et al. "Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil of Thymbra Spicata L. From Turkey." Natural Product Research, vol. 23, no. 6, 2009, pp. 572-9.
Unlü M, Vardar-Unlü G, Vural N, et al. Chemical composition, antibacterial and antifungal activity of the essential oil of Thymbra spicata L. from Turkey. Nat Prod Res. 2009;23(6):572-9.
Unlü, M., Vardar-Unlü, G., Vural, N., Dönmez, E., & Ozbaş, Z. Y. (2009). Chemical composition, antibacterial and antifungal activity of the essential oil of Thymbra spicata L. from Turkey. Natural Product Research, 23(6), 572-9. https://doi.org/10.1080/14786410802312316
Unlü M, et al. Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil of Thymbra Spicata L. From Turkey. Nat Prod Res. 2009;23(6):572-9. PubMed PMID: 19384734.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chemical composition, antibacterial and antifungal activity of the essential oil of Thymbra spicata L. from Turkey. AU - Unlü,Mehmet, AU - Vardar-Unlü,Gülhan, AU - Vural,Nilüfer, AU - Dönmez,Erol, AU - Ozbaş,Z Yeşim, PY - 2009/4/23/entrez PY - 2009/4/23/pubmed PY - 2009/6/17/medline SP - 572 EP - 9 JF - Natural product research JO - Nat Prod Res VL - 23 IS - 6 N2 - The composition of the essential oil from aerial parts of Thymbra spicata L. from Turkey was analysed by GC-MS and its in vitro antimicrobial activity was examined. GC-MS analysis of the essential oil resulted in the identification of twenty-three constituents, representing 97.04% of the oil. The major compounds detected in the essential oil were carvacrol (60.39%), gamma-terpinene (12.95%), and p-cymene (9.61%). The in vitro efficacy of the essential oil against 21 bacteria and seven Candida species was examined using disc diffusion and minimum inhibitory concentration (MIC) methods. The essential oil demonstrated strong anti-microbial activity in a wide spectrum against most microorganisms, particularly the yeasts tested. This is the first report on the anticandidal properties of the essential oil of T. spicata. In conclusion, this study confirms that T. spicata essential oil could be considered as a natural antimicrobial source. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/19384734/Chemical_composition_antibacterial_and_antifungal_activity_of_the_essential_oil_of_Thymbra_spicata_L__from_Turkey_ L2 - https://www.tandfonline.com/doi/full/10.1080/14786410802312316 DB - PRIME DP - Unbound Medicine ER -