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Modern concepts in the diagnosis and treatment of vitamin D deficiency and its clinical consequences.

Abstract

It is the purpose of this comprehensive report to outline a revolutionary strategy to prevent vitamin D deficiency in our nation. Vitamin D is a unique vitamin. Its metabolic product, calcitriol, is a profound secosteroid hormone that has impact on over 1000 genes in the human body. Recent clinical research has implicated vitamin D deficiency as a major factor in the etiology of rickets, a wide variety of cancers, as well as hypertension, stroke, heart attack, diabetes, bone fractures, periodontal disease, and even multiple sclerosis. There are two forms of vitamin D utilized in the human body: D2 and D3. Measurement of 25(OH)D is the most reliable method of detecting vitamin D deficiency. Several methods, including high-performance liquid chromatography (HPLC), chemoluminescence, and radioimmunoassay (RIA), have been developed for the measurement of total 25(OH)D levels. Prevention and treatment of vitamin D deficiency is accomplished by regulated sun exposure as well as vitamin D, supplementation. This information describing our plan to prevent vitamin D deficiency in the patients and employees of Legacy Health System is a landmark accomplishment that should be replicated in every healthcare setting in our country to prevent vitamin D deficiency.

Authors+Show Affiliations

University of Virginia Health System, Charlottesvill, VA, USA. richardedlich@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19392650

Citation

Edlich, Richard, et al. "Modern Concepts in the Diagnosis and Treatment of Vitamin D Deficiency and Its Clinical Consequences." Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society for Environmental Toxicology and Cancer, vol. 28, no. 1, 2009, pp. 1-4.
Edlich R, Fisher AL, Chase ME, et al. Modern concepts in the diagnosis and treatment of vitamin D deficiency and its clinical consequences. J Environ Pathol Toxicol Oncol. 2009;28(1):1-4.
Edlich, R., Fisher, A. L., Chase, M. E., Brock, C. M., Gubler, K., & Long, W. B. (2009). Modern concepts in the diagnosis and treatment of vitamin D deficiency and its clinical consequences. Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society for Environmental Toxicology and Cancer, 28(1), pp. 1-4.
Edlich R, et al. Modern Concepts in the Diagnosis and Treatment of Vitamin D Deficiency and Its Clinical Consequences. J Environ Pathol Toxicol Oncol. 2009;28(1):1-4. PubMed PMID: 19392650.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Modern concepts in the diagnosis and treatment of vitamin D deficiency and its clinical consequences. AU - Edlich,Richard, AU - Fisher,Allyson L, AU - Chase,Margot E, AU - Brock,Carroll M, AU - Gubler,K, AU - Long,William B,3rd PY - 2009/4/28/entrez PY - 2009/4/28/pubmed PY - 2009/7/9/medline SP - 1 EP - 4 JF - Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer JO - J. Environ. Pathol. Toxicol. Oncol. VL - 28 IS - 1 N2 - It is the purpose of this comprehensive report to outline a revolutionary strategy to prevent vitamin D deficiency in our nation. Vitamin D is a unique vitamin. Its metabolic product, calcitriol, is a profound secosteroid hormone that has impact on over 1000 genes in the human body. Recent clinical research has implicated vitamin D deficiency as a major factor in the etiology of rickets, a wide variety of cancers, as well as hypertension, stroke, heart attack, diabetes, bone fractures, periodontal disease, and even multiple sclerosis. There are two forms of vitamin D utilized in the human body: D2 and D3. Measurement of 25(OH)D is the most reliable method of detecting vitamin D deficiency. Several methods, including high-performance liquid chromatography (HPLC), chemoluminescence, and radioimmunoassay (RIA), have been developed for the measurement of total 25(OH)D levels. Prevention and treatment of vitamin D deficiency is accomplished by regulated sun exposure as well as vitamin D, supplementation. This information describing our plan to prevent vitamin D deficiency in the patients and employees of Legacy Health System is a landmark accomplishment that should be replicated in every healthcare setting in our country to prevent vitamin D deficiency. SN - 0731-8898 UR - https://www.unboundmedicine.com/medline/citation/19392650/Modern_concepts_in_the_diagnosis_and_treatment_of_vitamin_D_deficiency_and_its_clinical_consequences_ L2 - http://www.begellhouse.com/journals/0ff459a57a4c08d0,7591d8c6758993c4,775339e0721395d6.html DB - PRIME DP - Unbound Medicine ER -