Tags

Type your tag names separated by a space and hit enter

Modern concepts in the diagnosis and treatment of vitamin D deficiency and its clinical consequences.

Abstract

It is the purpose of this comprehensive report to outline a revolutionary strategy to prevent vitamin D deficiency in our nation. Vitamin D is a unique vitamin. Its metabolic product, calcitriol, is a profound secosteroid hormone that has impact on over 1000 genes in the human body. Recent clinical research has implicated vitamin D deficiency as a major factor in the etiology of rickets, a wide variety of cancers, as well as hypertension, stroke, heart attack, diabetes, bone fractures, periodontal disease, and even multiple sclerosis. There are two forms of vitamin D utilized in the human body: D2 and D3. Measurement of 25(OH)D is the most reliable method of detecting vitamin D deficiency. Several methods, including high-performance liquid chromatography (HPLC), chemoluminescence, and radioimmunoassay (RIA), have been developed for the measurement of total 25(OH)D levels. Prevention and treatment of vitamin D deficiency is accomplished by regulated sun exposure as well as vitamin D, supplementation. This information describing our plan to prevent vitamin D deficiency in the patients and employees of Legacy Health System is a landmark accomplishment that should be replicated in every healthcare setting in our country to prevent vitamin D deficiency.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    University of Virginia Health System, Charlottesvill, VA, USA. richardedlich@gmail.com

    , , , ,

    Source

    MeSH

    Chromatography, High Pressure Liquid
    Chromatography, Liquid
    Dietary Supplements
    Humans
    Sunlight
    Tandem Mass Spectrometry
    Trauma Centers
    Vitamin D
    Vitamin D Deficiency

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    19392650

    Citation

    Edlich, Richard, et al. "Modern Concepts in the Diagnosis and Treatment of Vitamin D Deficiency and Its Clinical Consequences." Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society for Environmental Toxicology and Cancer, vol. 28, no. 1, 2009, pp. 1-4.
    Edlich R, Fisher AL, Chase ME, et al. Modern concepts in the diagnosis and treatment of vitamin D deficiency and its clinical consequences. J Environ Pathol Toxicol Oncol. 2009;28(1):1-4.
    Edlich, R., Fisher, A. L., Chase, M. E., Brock, C. M., Gubler, K., & Long, W. B. (2009). Modern concepts in the diagnosis and treatment of vitamin D deficiency and its clinical consequences. Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society for Environmental Toxicology and Cancer, 28(1), pp. 1-4.
    Edlich R, et al. Modern Concepts in the Diagnosis and Treatment of Vitamin D Deficiency and Its Clinical Consequences. J Environ Pathol Toxicol Oncol. 2009;28(1):1-4. PubMed PMID: 19392650.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Modern concepts in the diagnosis and treatment of vitamin D deficiency and its clinical consequences. AU - Edlich,Richard, AU - Fisher,Allyson L, AU - Chase,Margot E, AU - Brock,Carroll M, AU - Gubler,K, AU - Long,William B,3rd PY - 2009/4/28/entrez PY - 2009/4/28/pubmed PY - 2009/7/9/medline SP - 1 EP - 4 JF - Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer JO - J. Environ. Pathol. Toxicol. Oncol. VL - 28 IS - 1 N2 - It is the purpose of this comprehensive report to outline a revolutionary strategy to prevent vitamin D deficiency in our nation. Vitamin D is a unique vitamin. Its metabolic product, calcitriol, is a profound secosteroid hormone that has impact on over 1000 genes in the human body. Recent clinical research has implicated vitamin D deficiency as a major factor in the etiology of rickets, a wide variety of cancers, as well as hypertension, stroke, heart attack, diabetes, bone fractures, periodontal disease, and even multiple sclerosis. There are two forms of vitamin D utilized in the human body: D2 and D3. Measurement of 25(OH)D is the most reliable method of detecting vitamin D deficiency. Several methods, including high-performance liquid chromatography (HPLC), chemoluminescence, and radioimmunoassay (RIA), have been developed for the measurement of total 25(OH)D levels. Prevention and treatment of vitamin D deficiency is accomplished by regulated sun exposure as well as vitamin D, supplementation. This information describing our plan to prevent vitamin D deficiency in the patients and employees of Legacy Health System is a landmark accomplishment that should be replicated in every healthcare setting in our country to prevent vitamin D deficiency. SN - 0731-8898 UR - https://www.unboundmedicine.com/medline/citation/19392650/Modern_concepts_in_the_diagnosis_and_treatment_of_vitamin_D_deficiency_and_its_clinical_consequences_ L2 - http://www.begellhouse.com/journals/0ff459a57a4c08d0,7591d8c6758993c4,775339e0721395d6.html DB - PRIME DP - Unbound Medicine ER -