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[The "Valle Belbo Project" for the prevention of ischemic heart disease: study design and correlations between alcohol and cardiovascular risk factors].

Abstract

BACKGROUND

The "Valle Belbo Project" is a primary prevention study on ischemic heart disease, aiming at identifying cardiovascular risk factors. Detailed data about the amount and kind of alcohol beverages used were assessed, too. The aims of the present study were to evaluate the prevalence of cardiovascular risk factors, and the relationships between alcohol and these factors.

METHODS

The study enrolled 3123 subjects, aged 20-65 years. Data about consumption of alcoholic drinks (amount and kind of beverages), smoking habits, physical activity during work, clinical and drug history were collected; height, weight, arterial blood pressure, fasting glycemia, and total cholesterol were also measured.

RESULTS

About 57% of the subjects consumed alcoholic drinks, mostly < 30 g/day (84%) and red wine only (80%). Prevalence of overweight/obesity, hypertension, hyperglycemia, hypercholesterolemia increased with higher amounts of alcohol consumed. A > 30 g/day alcohol use was independently associated with hypertension (odds ratio-OR 1.48, p = 0.03), hyperglycemia (OR 1.62, p = 0.02) overweight/obesity (OR 1.64, p = 0.003), and hypercholesterolemia (OR 1.69, p = 0.001) in a multiple logistic regression model, after multiple adjustments. A < 30 g/day red wine use was negatively correlated with hyperglycemia (OR 0.54, p < 0.0001) and overweight/obesity (OR 0.71, p = 0.002) with respect to consumption of higher or other kinds of alcoholic beverages in the same model.

CONCLUSIONS

Differently from heavy drinkers, < 30 g/day red wine drinkers are less frequently affected by overweight/obesity and hyperglycemia. Follow-up of these subjects may determine the role of alcohol effects in the incidence of ischemic heart disease.

Authors+Show Affiliations

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Divisione di Medicina, Ospedale Civile, Canelli, AT. bertolapl@iol.it

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Source

MeSH

Adult
Aged
Alcohol Drinking
Biomarkers
Blood Glucose
Blood Pressure Monitoring, Ambulatory
Body Mass Index
Cholesterol
Cohort Studies
Female
Follow-Up Studies
Health Surveys
Humans
Hypercholesterolemia
Hyperglycemia
Hypertension
Italy
Logistic Models
Male
Middle Aged
Motor Activity
Myocardial Ischemia
Obesity
Odds Ratio
Overweight
Prevalence
Research Design
Risk Factors
Smoking
Surveys and Questionnaires
Wine

Pub Type(s)

English Abstract
Journal Article
Multicenter Study

Language

ita

PubMed ID

19400055

Citation

Bertola, Pier Luigi, et al. "[The "Valle Belbo Project" for the Prevention of Ischemic Heart Disease: Study Design and Correlations Between Alcohol and Cardiovascular Risk Factors]." Italian Heart Journal. Supplement : Official Journal of the Italian Federation of Cardiology, vol. 4, no. 6, 2003, pp. 495-501.
Bertola PL, Stroppiana M, Favro M, et al. [The "Valle Belbo Project" for the prevention of ischemic heart disease: study design and correlations between alcohol and cardiovascular risk factors]. Ital Heart J Suppl. 2003;4(6):495-501.
Bertola, P. L., Stroppiana, M., Favro, M., Scassa, E., & Bo, S. (2003). [The "Valle Belbo Project" for the prevention of ischemic heart disease: study design and correlations between alcohol and cardiovascular risk factors]. Italian Heart Journal. Supplement : Official Journal of the Italian Federation of Cardiology, 4(6), pp. 495-501.
Bertola PL, et al. [The "Valle Belbo Project" for the Prevention of Ischemic Heart Disease: Study Design and Correlations Between Alcohol and Cardiovascular Risk Factors]. Ital Heart J Suppl. 2003;4(6):495-501. PubMed PMID: 19400055.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The "Valle Belbo Project" for the prevention of ischemic heart disease: study design and correlations between alcohol and cardiovascular risk factors]. AU - Bertola,Pier Luigi, AU - Stroppiana,Mauro, AU - Favro,Mauro, AU - Scassa,Enzo, AU - Bo,Simona, PY - 2009/4/30/entrez PY - 2003/6/1/pubmed PY - 2009/6/13/medline SP - 495 EP - 501 JF - Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology JO - Ital Heart J Suppl VL - 4 IS - 6 N2 - BACKGROUND: The "Valle Belbo Project" is a primary prevention study on ischemic heart disease, aiming at identifying cardiovascular risk factors. Detailed data about the amount and kind of alcohol beverages used were assessed, too. The aims of the present study were to evaluate the prevalence of cardiovascular risk factors, and the relationships between alcohol and these factors. METHODS: The study enrolled 3123 subjects, aged 20-65 years. Data about consumption of alcoholic drinks (amount and kind of beverages), smoking habits, physical activity during work, clinical and drug history were collected; height, weight, arterial blood pressure, fasting glycemia, and total cholesterol were also measured. RESULTS: About 57% of the subjects consumed alcoholic drinks, mostly < 30 g/day (84%) and red wine only (80%). Prevalence of overweight/obesity, hypertension, hyperglycemia, hypercholesterolemia increased with higher amounts of alcohol consumed. A > 30 g/day alcohol use was independently associated with hypertension (odds ratio-OR 1.48, p = 0.03), hyperglycemia (OR 1.62, p = 0.02) overweight/obesity (OR 1.64, p = 0.003), and hypercholesterolemia (OR 1.69, p = 0.001) in a multiple logistic regression model, after multiple adjustments. A < 30 g/day red wine use was negatively correlated with hyperglycemia (OR 0.54, p < 0.0001) and overweight/obesity (OR 0.71, p = 0.002) with respect to consumption of higher or other kinds of alcoholic beverages in the same model. CONCLUSIONS: Differently from heavy drinkers, < 30 g/day red wine drinkers are less frequently affected by overweight/obesity and hyperglycemia. Follow-up of these subjects may determine the role of alcohol effects in the incidence of ischemic heart disease. SN - 1129-4728 UR - https://www.unboundmedicine.com/medline/citation/19400055/[The_ L2 - http://www.diseaseinfosearch.org/result/130 DB - PRIME DP - Unbound Medicine ER -