Tags

Type your tag names separated by a space and hit enter

Looking for a pattern: an MEG study on the abstract mismatch negativity in musicians and nonmusicians.
BMC Neurosci. 2009 Apr 30; 10:42.BN

Abstract

BACKGROUND

The mismatch negativity (MMN) is an early component of event-related potentials/fields, which can be observed in response to violations of regularities in sound sequences. The MMN can be elicited by simple feature (e.g. pitch) deviations in standard oddball paradigms as well as by violations of more complex sequential patterns. By means of magnetoencephalography (MEG) we investigated if a pattern MMN could be elicited based on global rather than local probabilities and if the underlying ability to integrate long sequences of tones is enhanced in musicians compared to nonmusicians.

RESULTS

A pattern MMN was observed in response to violations of a predominant sequential pattern (AAAB) within a standard oddball tone sequence consisting of only two different tones. This pattern MMN was elicited even though the probability of pattern deviants in the sequence was as high as 0.5. Musicians showed more leftward-lateralized pattern MMN responses, which might be due to a stronger specialization of the ability to integrate information in a sequence of tones over a long time range.

CONCLUSION

The results indicate that auditory grouping and the probability distribution of possible patterns within a sequence influence the expectations about upcoming tones, and that the MMN might also be based on global statistical knowledge instead of a local memory trace. The results also show that auditory grouping based on sequential regularities can occur at a much slower presentation rate than previously presumed, and that probability distributions of possible patterns should be taken into account even for the construction of simple oddball sequences.

Authors+Show Affiliations

Institute for Biomagnetism and Biosignalanalysis, University of Münster, Malmedyweg 15, D-48149 Münster, Germany. sibylle.herholz@uni-muenster.deNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19405970

Citation

Herholz, Sibylle C., et al. "Looking for a Pattern: an MEG Study On the Abstract Mismatch Negativity in Musicians and Nonmusicians." BMC Neuroscience, vol. 10, 2009, p. 42.
Herholz SC, Lappe C, Pantev C. Looking for a pattern: an MEG study on the abstract mismatch negativity in musicians and nonmusicians. BMC Neurosci. 2009;10:42.
Herholz, S. C., Lappe, C., & Pantev, C. (2009). Looking for a pattern: an MEG study on the abstract mismatch negativity in musicians and nonmusicians. BMC Neuroscience, 10, 42. https://doi.org/10.1186/1471-2202-10-42
Herholz SC, Lappe C, Pantev C. Looking for a Pattern: an MEG Study On the Abstract Mismatch Negativity in Musicians and Nonmusicians. BMC Neurosci. 2009 Apr 30;10:42. PubMed PMID: 19405970.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Looking for a pattern: an MEG study on the abstract mismatch negativity in musicians and nonmusicians. AU - Herholz,Sibylle C, AU - Lappe,Claudia, AU - Pantev,Christo, Y1 - 2009/04/30/ PY - 2008/12/19/received PY - 2009/04/30/accepted PY - 2009/5/2/entrez PY - 2009/5/2/pubmed PY - 2009/7/1/medline SP - 42 EP - 42 JF - BMC neuroscience JO - BMC Neurosci VL - 10 N2 - BACKGROUND: The mismatch negativity (MMN) is an early component of event-related potentials/fields, which can be observed in response to violations of regularities in sound sequences. The MMN can be elicited by simple feature (e.g. pitch) deviations in standard oddball paradigms as well as by violations of more complex sequential patterns. By means of magnetoencephalography (MEG) we investigated if a pattern MMN could be elicited based on global rather than local probabilities and if the underlying ability to integrate long sequences of tones is enhanced in musicians compared to nonmusicians. RESULTS: A pattern MMN was observed in response to violations of a predominant sequential pattern (AAAB) within a standard oddball tone sequence consisting of only two different tones. This pattern MMN was elicited even though the probability of pattern deviants in the sequence was as high as 0.5. Musicians showed more leftward-lateralized pattern MMN responses, which might be due to a stronger specialization of the ability to integrate information in a sequence of tones over a long time range. CONCLUSION: The results indicate that auditory grouping and the probability distribution of possible patterns within a sequence influence the expectations about upcoming tones, and that the MMN might also be based on global statistical knowledge instead of a local memory trace. The results also show that auditory grouping based on sequential regularities can occur at a much slower presentation rate than previously presumed, and that probability distributions of possible patterns should be taken into account even for the construction of simple oddball sequences. SN - 1471-2202 UR - https://www.unboundmedicine.com/medline/citation/19405970/Looking_for_a_pattern:_an_MEG_study_on_the_abstract_mismatch_negativity_in_musicians_and_nonmusicians_ L2 - https://bmcneurosci.biomedcentral.com/articles/10.1186/1471-2202-10-42 DB - PRIME DP - Unbound Medicine ER -