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Increased risk of adverse pregnancy outcomes in women with rheumatoid arthritis: a nationwide population-based study.
Ann Rheum Dis. 2010 Apr; 69(4):715-7.AR

Abstract

OBJECTIVE

Using a 3-year nationwide population-based database (2001-3), this study aims to examine the relationship between rheumatoid arthritis (RA) and adverse pregnancy outcomes.

METHODS

The study used the Taiwan National Health Insurance Research Dataset and birth certificate registry. In total, 1912 mothers with RA and 9560 matched comparison mothers were included. Separate conditional logistic regression analyses were carried out to explore the risk of low birthweight (LBW), preterm births, small for gestational age (SGA) infants, preeclampsia and delivery mode (vaginal vs caesarean section (CS)) for the study and comparison groups.

RESULTS

Regression analyses showed that the adjusted odds of LBW, SGA infants, preeclampsia and CS for women with RA were 1.47 (95% CI 1.22 to 1.78), 1.20 (95% CI 1.05 to 1.38), 2.22 (95% CI 1.59 to 3.11) and 1.19 (95% CI 1.07 to 1.31) times, respectively, that of comparison mothers.

CONCLUSION

Women with RA had an increased risk of LBW, SGA babies, preeclampsia and CS compared with unaffected women.

Authors+Show Affiliations

School of Public Health, Taipei Medical University, 250 Wu-Hsing Street, Taipei 110, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19406733

Citation

Lin, Herng-Ching, et al. "Increased Risk of Adverse Pregnancy Outcomes in Women With Rheumatoid Arthritis: a Nationwide Population-based Study." Annals of the Rheumatic Diseases, vol. 69, no. 4, 2010, pp. 715-7.
Lin HC, Chen SF, Lin HC, et al. Increased risk of adverse pregnancy outcomes in women with rheumatoid arthritis: a nationwide population-based study. Ann Rheum Dis. 2010;69(4):715-7.
Lin, H. C., Chen, S. F., Lin, H. C., & Chen, Y. H. (2010). Increased risk of adverse pregnancy outcomes in women with rheumatoid arthritis: a nationwide population-based study. Annals of the Rheumatic Diseases, 69(4), 715-7. https://doi.org/10.1136/ard.2008.105262
Lin HC, et al. Increased Risk of Adverse Pregnancy Outcomes in Women With Rheumatoid Arthritis: a Nationwide Population-based Study. Ann Rheum Dis. 2010;69(4):715-7. PubMed PMID: 19406733.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Increased risk of adverse pregnancy outcomes in women with rheumatoid arthritis: a nationwide population-based study. AU - Lin,Herng-Ching, AU - Chen,Shu-Fen, AU - Lin,Hsiu-Chen, AU - Chen,Yi-Hua, Y1 - 2009/04/29/ PY - 2009/5/2/entrez PY - 2009/5/2/pubmed PY - 2010/4/17/medline SP - 715 EP - 7 JF - Annals of the rheumatic diseases JO - Ann Rheum Dis VL - 69 IS - 4 N2 - OBJECTIVE: Using a 3-year nationwide population-based database (2001-3), this study aims to examine the relationship between rheumatoid arthritis (RA) and adverse pregnancy outcomes. METHODS: The study used the Taiwan National Health Insurance Research Dataset and birth certificate registry. In total, 1912 mothers with RA and 9560 matched comparison mothers were included. Separate conditional logistic regression analyses were carried out to explore the risk of low birthweight (LBW), preterm births, small for gestational age (SGA) infants, preeclampsia and delivery mode (vaginal vs caesarean section (CS)) for the study and comparison groups. RESULTS: Regression analyses showed that the adjusted odds of LBW, SGA infants, preeclampsia and CS for women with RA were 1.47 (95% CI 1.22 to 1.78), 1.20 (95% CI 1.05 to 1.38), 2.22 (95% CI 1.59 to 3.11) and 1.19 (95% CI 1.07 to 1.31) times, respectively, that of comparison mothers. CONCLUSION: Women with RA had an increased risk of LBW, SGA babies, preeclampsia and CS compared with unaffected women. SN - 1468-2060 UR - https://www.unboundmedicine.com/medline/citation/19406733/Increased_risk_of_adverse_pregnancy_outcomes_in_women_with_rheumatoid_arthritis:_a_nationwide_population_based_study_ L2 - https://ard.bmj.com/lookup/pmidlookup?view=long&pmid=19406733 DB - PRIME DP - Unbound Medicine ER -