Tags

Type your tag names separated by a space and hit enter

Rapid identification of gallotannins from Chinese galls by matrix-assisted laser desorption/ionization time-of-flight quadrupole ion trap mass spectrometry.
Rapid Commun Mass Spectrom. 2009 Jun; 23(11):1678-82.RC

Abstract

Chinese gall, a conventional traditional Chinese medicine, contains high levels of gallotannins. A rapid method for direct analysis of the gallotannins without using any troublesome sample pretreatments was developed using matrix-assisted laser desorption/ionization time-of-flight quadrupole ion trap mass spectrometry (MALDI-QIT-TOF MS) to successfully identify the gallotannin components in the crude extract of Chinese galls within several minutes. The high quality of the MS and MS(2) spectra acquired clearly showed that hydrolysable tannins in Chinese galls were identified as a series of the gallotannins with degrees of polymerization (DP) of 4-11 galloyl units. The MS(2) data indicated that the identified gallotannins with DP of 4-7 galloyl units had clear fragmentation with loss of 1-5 galloyl units which were further deprived of 1-3 water moieties. This technique may be used for rapid evaluation and screening of hydrolysable tannins in medicinal plants.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Zhu F
School of Biological Sciences, The University of Hong Kong, Pokfulam Road, Hong Kong.
Cai YZ
No affiliation info available
Xing J
No affiliation info available
Ke J
No affiliation info available
Zhan Z
No affiliation info available
Corke H
No affiliation info available

MeSH

Drugs, Chinese HerbalHydrolyzable TanninsPlants, MedicinalSpectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Pub Type(s)

Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19408344

Citation

Zhu, Fan, et al. "Rapid Identification of Gallotannins From Chinese Galls By Matrix-assisted Laser Desorption/ionization Time-of-flight Quadrupole Ion Trap Mass Spectrometry." Rapid Communications in Mass Spectrometry : RCM, vol. 23, no. 11, 2009, pp. 1678-82.
Zhu F, Cai YZ, Xing J, et al. Rapid identification of gallotannins from Chinese galls by matrix-assisted laser desorption/ionization time-of-flight quadrupole ion trap mass spectrometry. Rapid Commun Mass Spectrom. 2009;23(11):1678-82.
Zhu, F., Cai, Y. Z., Xing, J., Ke, J., Zhan, Z., & Corke, H. (2009). Rapid identification of gallotannins from Chinese galls by matrix-assisted laser desorption/ionization time-of-flight quadrupole ion trap mass spectrometry. Rapid Communications in Mass Spectrometry : RCM, 23(11), 1678-82. https://doi.org/10.1002/rcm.4064
Zhu F, et al. Rapid Identification of Gallotannins From Chinese Galls By Matrix-assisted Laser Desorption/ionization Time-of-flight Quadrupole Ion Trap Mass Spectrometry. Rapid Commun Mass Spectrom. 2009;23(11):1678-82. PubMed PMID: 19408344.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Rapid identification of gallotannins from Chinese galls by matrix-assisted laser desorption/ionization time-of-flight quadrupole ion trap mass spectrometry. AU - Zhu,Fan, AU - Cai,Yi-Zhong, AU - Xing,Jie, AU - Ke,Jinxia, AU - Zhan,Zhaoqi, AU - Corke,Harold, PY - 2009/5/2/entrez PY - 2009/5/2/pubmed PY - 2009/8/12/medline SP - 1678 EP - 82 JF - Rapid communications in mass spectrometry : RCM JO - Rapid Commun Mass Spectrom VL - 23 IS - 11 N2 - Chinese gall, a conventional traditional Chinese medicine, contains high levels of gallotannins. A rapid method for direct analysis of the gallotannins without using any troublesome sample pretreatments was developed using matrix-assisted laser desorption/ionization time-of-flight quadrupole ion trap mass spectrometry (MALDI-QIT-TOF MS) to successfully identify the gallotannin components in the crude extract of Chinese galls within several minutes. The high quality of the MS and MS(2) spectra acquired clearly showed that hydrolysable tannins in Chinese galls were identified as a series of the gallotannins with degrees of polymerization (DP) of 4-11 galloyl units. The MS(2) data indicated that the identified gallotannins with DP of 4-7 galloyl units had clear fragmentation with loss of 1-5 galloyl units which were further deprived of 1-3 water moieties. This technique may be used for rapid evaluation and screening of hydrolysable tannins in medicinal plants. SN - 1097-0231 UR - https://www.unboundmedicine.com/medline/citation/19408344/Rapid_identification_of_gallotannins_from_Chinese_galls_by_matrix_assisted_laser_desorption/ionization_time_of_flight_quadrupole_ion_trap_mass_spectrometry_ L2 - https://doi.org/10.1002/rcm.4064 DB - PRIME DP - Unbound Medicine ER -
Grapherence [↓3]

Related Citations

More