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Comparison of oral midazolam with a combination of oral midazolam and nitrous oxide-oxygen inhalation in the effectiveness of dental sedation for young children.
J Indian Soc Pedod Prev Dent. 2009 Jan-Mar; 27(1):9-16.JI

Abstract

AIM

To compare the effectiveness of 0.6 mg/kg oral midazolam sedation alone and a combination of 0.6 mg/kg oral midazolam plus nitrous oxide-oxygen inhalation sedation, in controlling the behavior of uncooperative children during dental treatment.

STUDY DESIGN

The study had a crossover design where the same patient received two different sedation regimens, that is, oral midazolam 0.6 mg/kg and oral midazolam 0.6 mg/kg with nitrous oxide-oxygen inhalation during two dental treatment visits.

MATERIALS AND METHODS

Thirty children (17 males and 13 females) were randomly selected for the study, with a mean age of 55.07 (+/- 9.29) months, ranging from 48 - 72 months. A scoring system suggested by Houpt et al. (1985) was utilized for assessment of the children's behavior.

RESULTS

There was no significant (p > 0.05) difference in the overall behavior assessment between the two sedation regimens, that is, oral midazolam alone and oral midazolam plus nitrous oxide-oxygen. However, the combination of midazolam and nitrous oxide-oxygen showed significantly (p < 0.05) superior results as compared to midazolam alone, in terms of controlling movement and crying during local anesthesia administration and restorative procedures.

CONCLUSION

Compared to oral midazolam alone, a combination of oral midazolam and nitrous oxide inhalation sedation appears to provide more comfort to pediatric dental patients and operators during critical stages of dental treatment.

Authors+Show Affiliations

Security Forces Hospital, Makkah Al-Mukarrama, Saudi Arabia.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

19414968

Citation

Al-Zahrani, A M., et al. "Comparison of Oral Midazolam With a Combination of Oral Midazolam and Nitrous Oxide-oxygen Inhalation in the Effectiveness of Dental Sedation for Young Children." Journal of the Indian Society of Pedodontics and Preventive Dentistry, vol. 27, no. 1, 2009, pp. 9-16.
Al-Zahrani AM, Wyne AH, Sheta SA. Comparison of oral midazolam with a combination of oral midazolam and nitrous oxide-oxygen inhalation in the effectiveness of dental sedation for young children. J Indian Soc Pedod Prev Dent. 2009;27(1):9-16.
Al-Zahrani, A. M., Wyne, A. H., & Sheta, S. A. (2009). Comparison of oral midazolam with a combination of oral midazolam and nitrous oxide-oxygen inhalation in the effectiveness of dental sedation for young children. Journal of the Indian Society of Pedodontics and Preventive Dentistry, 27(1), 9-16. https://doi.org/10.4103/0970-4388.50810
Al-Zahrani AM, Wyne AH, Sheta SA. Comparison of Oral Midazolam With a Combination of Oral Midazolam and Nitrous Oxide-oxygen Inhalation in the Effectiveness of Dental Sedation for Young Children. J Indian Soc Pedod Prev Dent. 2009 Jan-Mar;27(1):9-16. PubMed PMID: 19414968.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of oral midazolam with a combination of oral midazolam and nitrous oxide-oxygen inhalation in the effectiveness of dental sedation for young children. AU - Al-Zahrani,A M, AU - Wyne,Amjad H, AU - Sheta,S A, PY - 2009/5/6/entrez PY - 2009/5/6/pubmed PY - 2009/8/25/medline SP - 9 EP - 16 JF - Journal of the Indian Society of Pedodontics and Preventive Dentistry JO - J Indian Soc Pedod Prev Dent VL - 27 IS - 1 N2 - AIM: To compare the effectiveness of 0.6 mg/kg oral midazolam sedation alone and a combination of 0.6 mg/kg oral midazolam plus nitrous oxide-oxygen inhalation sedation, in controlling the behavior of uncooperative children during dental treatment. STUDY DESIGN: The study had a crossover design where the same patient received two different sedation regimens, that is, oral midazolam 0.6 mg/kg and oral midazolam 0.6 mg/kg with nitrous oxide-oxygen inhalation during two dental treatment visits. MATERIALS AND METHODS: Thirty children (17 males and 13 females) were randomly selected for the study, with a mean age of 55.07 (+/- 9.29) months, ranging from 48 - 72 months. A scoring system suggested by Houpt et al. (1985) was utilized for assessment of the children's behavior. RESULTS: There was no significant (p > 0.05) difference in the overall behavior assessment between the two sedation regimens, that is, oral midazolam alone and oral midazolam plus nitrous oxide-oxygen. However, the combination of midazolam and nitrous oxide-oxygen showed significantly (p < 0.05) superior results as compared to midazolam alone, in terms of controlling movement and crying during local anesthesia administration and restorative procedures. CONCLUSION: Compared to oral midazolam alone, a combination of oral midazolam and nitrous oxide inhalation sedation appears to provide more comfort to pediatric dental patients and operators during critical stages of dental treatment. SN - 0970-4388 UR - https://www.unboundmedicine.com/medline/citation/19414968/Comparison_of_oral_midazolam_with_a_combination_of_oral_midazolam_and_nitrous_oxide_oxygen_inhalation_in_the_effectiveness_of_dental_sedation_for_young_children_ DB - PRIME DP - Unbound Medicine ER -