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Antifungal potential of essential oil and various organic extracts of Nandina domestica Thunb. against skin infectious fungal pathogens.
Appl Microbiol Biotechnol. 2009 Jul; 83(6):1127-33.AM

Abstract

This study was undertaken to assess the in vitro antifungal potential of the essential oil and n-hexane, chloroform, ethyl acetate, and methanol extracts of Nandina domestica Thunb. against dermatophytes, the casual agents of superficial infections in animals and human beings. The oil (1,000 microg/disc) and extracts (1,500 microg/disc) revealed 31.1-68.6% and 19.2-55.1% antidermatophytic effect against Trichophyton rubrum KCTC 6345, T. rubrum KCTC 6375, T. rubrum KCTC 6352, Trichophyton mentagrophytes KCTC 6085, T. mentagrophytes KCTC 6077, T. mentagrophytes KCTC 6316, Microsporum canis KCTC 6591, M. canis KCTC 6348, and M. canis KCTC 6349, respectively, along with their respective minimum inhibitory concentration values ranging from 62.5 to 500 and 125 to 2,000 microg/ml. Also, the oil had strong detrimental effect on spore germination of all the tested dermatophytic fungi as well as concentration and time-dependent kinetic inhibition of T. rubrum KCTC 6375. The present results demonstrated that N. domestica mediated oil and extracts could be potential sources of natural fungicides to control certain important dermatophytic fungi.

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Authors+Show Affiliations

Bajpai VK
Department of Biotechnology, Daegu University, Kyoungsan, Kyoungbook, Republic of Korea.
Yoon JI
No affiliation info available
Kang SC
No affiliation info available

MeSH

AnimalsAntifungal AgentsArthrodermataceaeBerberidaceaeDose-Response Relationship, DrugHumansMicrobial Sensitivity TestsOils, VolatileOrganic ChemicalsSpores, FungalTime Factors

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19415265

Citation

Bajpai, Vivek K., et al. "Antifungal Potential of Essential Oil and Various Organic Extracts of Nandina Domestica Thunb. Against Skin Infectious Fungal Pathogens." Applied Microbiology and Biotechnology, vol. 83, no. 6, 2009, pp. 1127-33.
Bajpai VK, Yoon JI, Kang SC. Antifungal potential of essential oil and various organic extracts of Nandina domestica Thunb. against skin infectious fungal pathogens. Appl Microbiol Biotechnol. 2009;83(6):1127-33.
Bajpai, V. K., Yoon, J. I., & Kang, S. C. (2009). Antifungal potential of essential oil and various organic extracts of Nandina domestica Thunb. against skin infectious fungal pathogens. Applied Microbiology and Biotechnology, 83(6), 1127-33. https://doi.org/10.1007/s00253-009-2017-5
Bajpai VK, Yoon JI, Kang SC. Antifungal Potential of Essential Oil and Various Organic Extracts of Nandina Domestica Thunb. Against Skin Infectious Fungal Pathogens. Appl Microbiol Biotechnol. 2009;83(6):1127-33. PubMed PMID: 19415265.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antifungal potential of essential oil and various organic extracts of Nandina domestica Thunb. against skin infectious fungal pathogens. AU - Bajpai,Vivek K, AU - Yoon,Jung In, AU - Kang,Sun Chul, Y1 - 2009/05/05/ PY - 2009/03/02/received PY - 2009/04/18/accepted PY - 2009/04/16/revised PY - 2009/5/6/entrez PY - 2009/5/6/pubmed PY - 2009/8/27/medline SP - 1127 EP - 33 JF - Applied microbiology and biotechnology JO - Appl Microbiol Biotechnol VL - 83 IS - 6 N2 - This study was undertaken to assess the in vitro antifungal potential of the essential oil and n-hexane, chloroform, ethyl acetate, and methanol extracts of Nandina domestica Thunb. against dermatophytes, the casual agents of superficial infections in animals and human beings. The oil (1,000 microg/disc) and extracts (1,500 microg/disc) revealed 31.1-68.6% and 19.2-55.1% antidermatophytic effect against Trichophyton rubrum KCTC 6345, T. rubrum KCTC 6375, T. rubrum KCTC 6352, Trichophyton mentagrophytes KCTC 6085, T. mentagrophytes KCTC 6077, T. mentagrophytes KCTC 6316, Microsporum canis KCTC 6591, M. canis KCTC 6348, and M. canis KCTC 6349, respectively, along with their respective minimum inhibitory concentration values ranging from 62.5 to 500 and 125 to 2,000 microg/ml. Also, the oil had strong detrimental effect on spore germination of all the tested dermatophytic fungi as well as concentration and time-dependent kinetic inhibition of T. rubrum KCTC 6375. The present results demonstrated that N. domestica mediated oil and extracts could be potential sources of natural fungicides to control certain important dermatophytic fungi. SN - 1432-0614 UR - https://www.unboundmedicine.com/medline/citation/19415265/Antifungal_potential_of_essential_oil_and_various_organic_extracts_of_Nandina_domestica_Thunb__against_skin_infectious_fungal_pathogens_ L2 - https://dx.doi.org/10.1007/s00253-009-2017-5 DB - PRIME DP - Unbound Medicine ER -