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The role of acetaldehyde and glycerol in the adaptation to ethanol stress of Saccharomyces cerevisiae and other yeasts.FEMS Yeast Res. 2009 May; 9(3):365-71.FY
Abstract
Ethanol inhibition is a commonly encountered stress condition during typical yeast fermentations and often results in reduced fermentation rates and production yields. While past studies have shown that acetaldehyde addition has a significant ameliorating effect on the growth of ethanol-stressed Saccharomyces cerevisiae, this study investigated the potential ameliorating effect of acetaldehyde on a wide range of ethanol-stressed yeasts. Acetaldehyde does not appear to be a universal ameliorating agent for yeasts exposed to ethanol stress. It is also shown that as a result of an ethanol stress, most yeasts rapidly produce glycerol as an alternative means of NAD(+) regeneration rather than having a specific requirement for glycerol. The results strongly suggest that both ethanol and acetaldehyde exposure have a direct effect on the cellular NAD(+)/NADH ratio, which can manifest itself as modulations in glycerol production.
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Pub Type(s)
Journal Article
Research Support, Non-U.S. Gov't
Language
eng
PubMed ID
19416102
Citation
Vriesekoop, Frank, et al. "The Role of Acetaldehyde and Glycerol in the Adaptation to Ethanol Stress of Saccharomyces Cerevisiae and Other Yeasts." FEMS Yeast Research, vol. 9, no. 3, 2009, pp. 365-71.
Vriesekoop F, Haass C, Pamment NB. The role of acetaldehyde and glycerol in the adaptation to ethanol stress of Saccharomyces cerevisiae and other yeasts. FEMS Yeast Res. 2009;9(3):365-71.
Vriesekoop, F., Haass, C., & Pamment, N. B. (2009). The role of acetaldehyde and glycerol in the adaptation to ethanol stress of Saccharomyces cerevisiae and other yeasts. FEMS Yeast Research, 9(3), 365-71. https://doi.org/10.1111/j.1567-1364.2009.00492.x
Vriesekoop F, Haass C, Pamment NB. The Role of Acetaldehyde and Glycerol in the Adaptation to Ethanol Stress of Saccharomyces Cerevisiae and Other Yeasts. FEMS Yeast Res. 2009;9(3):365-71. PubMed PMID: 19416102.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - The role of acetaldehyde and glycerol in the adaptation to ethanol stress of Saccharomyces cerevisiae and other yeasts.
AU - Vriesekoop,Frank,
AU - Haass,Cornelia,
AU - Pamment,Neville B,
PY - 2009/5/7/entrez
PY - 2009/5/7/pubmed
PY - 2009/7/31/medline
SP - 365
EP - 71
JF - FEMS yeast research
JO - FEMS Yeast Res
VL - 9
IS - 3
N2 - Ethanol inhibition is a commonly encountered stress condition during typical yeast fermentations and often results in reduced fermentation rates and production yields. While past studies have shown that acetaldehyde addition has a significant ameliorating effect on the growth of ethanol-stressed Saccharomyces cerevisiae, this study investigated the potential ameliorating effect of acetaldehyde on a wide range of ethanol-stressed yeasts. Acetaldehyde does not appear to be a universal ameliorating agent for yeasts exposed to ethanol stress. It is also shown that as a result of an ethanol stress, most yeasts rapidly produce glycerol as an alternative means of NAD(+) regeneration rather than having a specific requirement for glycerol. The results strongly suggest that both ethanol and acetaldehyde exposure have a direct effect on the cellular NAD(+)/NADH ratio, which can manifest itself as modulations in glycerol production.
SN - 1567-1364
UR - https://www.unboundmedicine.com/medline/citation/19416102/The_role_of_acetaldehyde_and_glycerol_in_the_adaptation_to_ethanol_stress_of_Saccharomyces_cerevisiae_and_other_yeasts_
L2 - https://academic.oup.com/femsyr/article-lookup/doi/10.1111/j.1567-1364.2009.00492.x
DB - PRIME
DP - Unbound Medicine
ER -
