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Alcohol and cardiovascular diseases.
Expert Rev Cardiovasc Ther. 2009 May; 7(5):499-506.ER

Abstract

With respect to cardiovascular disorders, epidemiologic studies support the hypothesis of increased risks among heavy alcohol drinkers and indicate a lower risk among lighter drinkers. Increased cardiovascular risks of heavy drinking include cardiomyopathy, systemic hypertension, supraventricular arrhythmias, hemorrhagic stroke and heart failure that is not associated with coronary artery disease (CAD). Light-to-moderate drinking is probably unrelated to increased risk of any cardiovascular condition and is related to lower risks of CAD, ischemic stroke and CAD-related heart failure. A protective alcohol-CAD hypothesis is supported by plausible biological mechanisms attributable to ethyl alcohol. Possible nonalcohol beneficial components in wine (especially red) could explain the extra protection of wine, but a healthier pattern of drinking or more favorable risk traits in wine drinkers may also be involved. Advice regarding the advisability of alcohol drinking for health needs to be individualized according to specific risks and benefits.

Authors+Show Affiliations

Kaiser Permanente Oakland Medical Center, 280 West MacArthur Boulevard, Oakland, CA 94611, USA. arthur.klatsky@kp.org

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19419257

Citation

Klatsky, Arthur L.. "Alcohol and Cardiovascular Diseases." Expert Review of Cardiovascular Therapy, vol. 7, no. 5, 2009, pp. 499-506.
Klatsky AL. Alcohol and cardiovascular diseases. Expert Rev Cardiovasc Ther. 2009;7(5):499-506.
Klatsky, A. L. (2009). Alcohol and cardiovascular diseases. Expert Review of Cardiovascular Therapy, 7(5), 499-506. https://doi.org/10.1586/erc.09.22
Klatsky AL. Alcohol and Cardiovascular Diseases. Expert Rev Cardiovasc Ther. 2009;7(5):499-506. PubMed PMID: 19419257.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alcohol and cardiovascular diseases. A1 - Klatsky,Arthur L, PY - 2009/5/8/entrez PY - 2009/5/8/pubmed PY - 2009/8/25/medline SP - 499 EP - 506 JF - Expert review of cardiovascular therapy JO - Expert Rev Cardiovasc Ther VL - 7 IS - 5 N2 - With respect to cardiovascular disorders, epidemiologic studies support the hypothesis of increased risks among heavy alcohol drinkers and indicate a lower risk among lighter drinkers. Increased cardiovascular risks of heavy drinking include cardiomyopathy, systemic hypertension, supraventricular arrhythmias, hemorrhagic stroke and heart failure that is not associated with coronary artery disease (CAD). Light-to-moderate drinking is probably unrelated to increased risk of any cardiovascular condition and is related to lower risks of CAD, ischemic stroke and CAD-related heart failure. A protective alcohol-CAD hypothesis is supported by plausible biological mechanisms attributable to ethyl alcohol. Possible nonalcohol beneficial components in wine (especially red) could explain the extra protection of wine, but a healthier pattern of drinking or more favorable risk traits in wine drinkers may also be involved. Advice regarding the advisability of alcohol drinking for health needs to be individualized according to specific risks and benefits. SN - 1744-8344 UR - https://www.unboundmedicine.com/medline/citation/19419257/Alcohol_and_cardiovascular_diseases_ L2 - http://www.tandfonline.com/doi/full/10.1586/erc.09.22 DB - PRIME DP - Unbound Medicine ER -