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Traffic exposure associated with allergic asthma and allergic rhinitis in adults. A cross-sectional study in southern Sweden.
Int J Health Geogr. 2009 May 06; 8:25.IJ

Abstract

BACKGROUND

There is conflicting evidence that traffic-related air pollution is a risk factor for allergic conditions. Few studies have investigated this in adults. In adults, a high proportion of asthma, rhinitis and eczema is triggered by non-allergic factors. We investigated traffic as a risk factor for allergic versus non-allergic asthma and rhinitis, and eczema, in adults. A questionnaire from 2000 (n = 9319, 18-77 years) provided individual data about disease outcome and self-reported traffic exposure. Additional exposure assessments were obtained using Geographical Informations Systems (GIS). Residential addresses were linked to the national Swedish Road Database and to a pollutant database with modelled annual means of NOx (Nitrogen Oxids).

RESULTS

Living within 100 m from a road with a traffic intensity of >10 cars/min (24 hour mean) was associated with prevalence of current asthma reported to be triggered by allergic factors (OR = 1.83, 95% CI = 1.23-2.72) and with allergic rhinitis (OR = 1.30, 95%CI = (1.05-1.61). No relation was seen with asthma or rhinitis triggered by other factors. Living within 100 m of a road with >10 cars/min was also associated with hand-eczema during the last 12 months (OR = 1.63, 95% CI = 1.19-2.23), but not with allergic eczema or diagnosed hand-eczema. Consistent results were seen using self-reported traffic, but the associations with NOx were less consistent.

CONCLUSION

Exposure to traffic was associated with a higher prevalence of allergic asthma and allergic rhinitis, but not with asthma or rhinitis triggered by non-allergic factors. This difference was suggested by the overall pattern, but only clear using GIS-measured traffic intensity as a proxy for traffic exposure. An association was also found with hand-eczema during the last 12 months. We suggest that asthma and rhinitis should not be treated as homogenous groups when estimating effects from traffic in adults.

Authors+Show Affiliations

Department of Occupational and Environmental Medicine, Lund University, Sweden. anna.lindgren@med.lu.seNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19419561

Citation

Lindgren, Anna, et al. "Traffic Exposure Associated With Allergic Asthma and Allergic Rhinitis in Adults. a Cross-sectional Study in Southern Sweden." International Journal of Health Geographics, vol. 8, 2009, p. 25.
Lindgren A, Stroh E, Nihlén U, et al. Traffic exposure associated with allergic asthma and allergic rhinitis in adults. A cross-sectional study in southern Sweden. Int J Health Geogr. 2009;8:25.
Lindgren, A., Stroh, E., Nihlén, U., Montnémery, P., Axmon, A., & Jakobsson, K. (2009). Traffic exposure associated with allergic asthma and allergic rhinitis in adults. A cross-sectional study in southern Sweden. International Journal of Health Geographics, 8, 25. https://doi.org/10.1186/1476-072X-8-25
Lindgren A, et al. Traffic Exposure Associated With Allergic Asthma and Allergic Rhinitis in Adults. a Cross-sectional Study in Southern Sweden. Int J Health Geogr. 2009 May 6;8:25. PubMed PMID: 19419561.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Traffic exposure associated with allergic asthma and allergic rhinitis in adults. A cross-sectional study in southern Sweden. AU - Lindgren,Anna, AU - Stroh,Emilie, AU - Nihlén,Ulf, AU - Montnémery,Peter, AU - Axmon,Anna, AU - Jakobsson,Kristina, Y1 - 2009/05/06/ PY - 2009/01/27/received PY - 2009/05/06/accepted PY - 2009/5/8/entrez PY - 2009/5/8/pubmed PY - 2009/8/4/medline SP - 25 EP - 25 JF - International journal of health geographics JO - Int J Health Geogr VL - 8 N2 - BACKGROUND: There is conflicting evidence that traffic-related air pollution is a risk factor for allergic conditions. Few studies have investigated this in adults. In adults, a high proportion of asthma, rhinitis and eczema is triggered by non-allergic factors. We investigated traffic as a risk factor for allergic versus non-allergic asthma and rhinitis, and eczema, in adults. A questionnaire from 2000 (n = 9319, 18-77 years) provided individual data about disease outcome and self-reported traffic exposure. Additional exposure assessments were obtained using Geographical Informations Systems (GIS). Residential addresses were linked to the national Swedish Road Database and to a pollutant database with modelled annual means of NOx (Nitrogen Oxids). RESULTS: Living within 100 m from a road with a traffic intensity of >10 cars/min (24 hour mean) was associated with prevalence of current asthma reported to be triggered by allergic factors (OR = 1.83, 95% CI = 1.23-2.72) and with allergic rhinitis (OR = 1.30, 95%CI = (1.05-1.61). No relation was seen with asthma or rhinitis triggered by other factors. Living within 100 m of a road with >10 cars/min was also associated with hand-eczema during the last 12 months (OR = 1.63, 95% CI = 1.19-2.23), but not with allergic eczema or diagnosed hand-eczema. Consistent results were seen using self-reported traffic, but the associations with NOx were less consistent. CONCLUSION: Exposure to traffic was associated with a higher prevalence of allergic asthma and allergic rhinitis, but not with asthma or rhinitis triggered by non-allergic factors. This difference was suggested by the overall pattern, but only clear using GIS-measured traffic intensity as a proxy for traffic exposure. An association was also found with hand-eczema during the last 12 months. We suggest that asthma and rhinitis should not be treated as homogenous groups when estimating effects from traffic in adults. SN - 1476-072X UR - https://www.unboundmedicine.com/medline/citation/19419561/Traffic_exposure_associated_with_allergic_asthma_and_allergic_rhinitis_in_adults__A_cross_sectional_study_in_southern_Sweden_ L2 - https://ij-healthgeographics.biomedcentral.com/articles/10.1186/1476-072X-8-25 DB - PRIME DP - Unbound Medicine ER -