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Antioxidant activity and total phenolic content of ethanolic extract of Caesalpinia bonducella seeds.
Food Chem Toxicol. 2009 Aug; 47(8):1848-51.FC

Abstract

The aim of this study was to assess the in vitro potential of ethanolic extract of Caesalpinia bonducella seeds as a natural antioxidant. The DPPH activity of the extract (20, 40, 50, 100 and 200 microg/ml) was increased in a dose dependent manner, which was found in the range of 38.93-74.77% as compared to ascorbic acid (64.26-82.58%). The IC(50) values of ethanolic extract and ascorbic acid in DPPH radical scavenging assay were obtained to be 74.73 and 26.68 microg/ml, respectively. The ethanolic extract was also found to scavenge the superoxide generated by EDTA/NBT system. Measurement of total phenolic content of the ethanolic extract of C. bonducella was achieved using Folin-Ciocalteau reagent containing 62.50mg/g of phenolic content, which was found significantly higher when compared to reference standard gallic acid. The ethanolic extract also inhibited the hydroxyl radical, nitric oxide, superoxide anions with IC(50) values of 109.85, 102.65 and 89.84 microg/ml, respectively. However, the IC(50) values for the standard ascorbic acid were noted to be 70.79, 65.98 and 36.68 microg/ml respectively. The results obtained in this study clearly indicate that C. bonducella has a significant potential to use as a natural antioxidant agent.

Authors+Show Affiliations

Faculty of Life Sciences, Department of Botany, Dr. H.S. Gour University, Sagar 470 003, Madhya Pradesh, India. s.microb@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19422871

Citation

Shukla, Shruti, et al. "Antioxidant Activity and Total Phenolic Content of Ethanolic Extract of Caesalpinia Bonducella Seeds." Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association, vol. 47, no. 8, 2009, pp. 1848-51.
Shukla S, Mehta A, John J, et al. Antioxidant activity and total phenolic content of ethanolic extract of Caesalpinia bonducella seeds. Food Chem Toxicol. 2009;47(8):1848-51.
Shukla, S., Mehta, A., John, J., Singh, S., Mehta, P., & Vyas, S. P. (2009). Antioxidant activity and total phenolic content of ethanolic extract of Caesalpinia bonducella seeds. Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association, 47(8), 1848-51. https://doi.org/10.1016/j.fct.2009.04.040
Shukla S, et al. Antioxidant Activity and Total Phenolic Content of Ethanolic Extract of Caesalpinia Bonducella Seeds. Food Chem Toxicol. 2009;47(8):1848-51. PubMed PMID: 19422871.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant activity and total phenolic content of ethanolic extract of Caesalpinia bonducella seeds. AU - Shukla,Shruti, AU - Mehta,Archana, AU - John,Jinu, AU - Singh,Siddharth, AU - Mehta,Pradeep, AU - Vyas,Suresh Prasad, Y1 - 2009/05/05/ PY - 2008/10/30/received PY - 2009/04/26/revised PY - 2009/04/27/accepted PY - 2009/5/9/entrez PY - 2009/5/9/pubmed PY - 2009/10/20/medline SP - 1848 EP - 51 JF - Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association JO - Food Chem Toxicol VL - 47 IS - 8 N2 - The aim of this study was to assess the in vitro potential of ethanolic extract of Caesalpinia bonducella seeds as a natural antioxidant. The DPPH activity of the extract (20, 40, 50, 100 and 200 microg/ml) was increased in a dose dependent manner, which was found in the range of 38.93-74.77% as compared to ascorbic acid (64.26-82.58%). The IC(50) values of ethanolic extract and ascorbic acid in DPPH radical scavenging assay were obtained to be 74.73 and 26.68 microg/ml, respectively. The ethanolic extract was also found to scavenge the superoxide generated by EDTA/NBT system. Measurement of total phenolic content of the ethanolic extract of C. bonducella was achieved using Folin-Ciocalteau reagent containing 62.50mg/g of phenolic content, which was found significantly higher when compared to reference standard gallic acid. The ethanolic extract also inhibited the hydroxyl radical, nitric oxide, superoxide anions with IC(50) values of 109.85, 102.65 and 89.84 microg/ml, respectively. However, the IC(50) values for the standard ascorbic acid were noted to be 70.79, 65.98 and 36.68 microg/ml respectively. The results obtained in this study clearly indicate that C. bonducella has a significant potential to use as a natural antioxidant agent. SN - 1873-6351 UR - https://www.unboundmedicine.com/medline/citation/19422871/Antioxidant_activity_and_total_phenolic_content_of_ethanolic_extract_of_Caesalpinia_bonducella_seeds_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0278-6915(09)00210-5 DB - PRIME DP - Unbound Medicine ER -