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Cortisol-induced enhancement of emotional face processing in social phobia depends on symptom severity and motivational context.
Biol Psychol. 2009 May; 81(2):123-30.BP

Abstract

We investigated the effects of cortisol administration on approach and avoidance tendencies in 20 patients with social anxiety disorder (SAD). Event-related brain potentials (ERPs) were measured during a reaction time task, in which patients evaluated the emotional expression of photographs of happy and angry faces by making an approaching (flexion) or avoiding (extension) arm movement. Patients showed significant avoidance tendencies for angry but not for happy faces, both in the placebo and cortisol condition. Moreover, ERP analyses showed a significant interaction of condition by severity of social anxiety on early positive (P150) amplitudes during avoidance compared to approach, indicating that cortisol increases early processing of social stimuli (in particular angry faces) during avoidance. This result replicates previous findings from a non-clinical sample of high anxious individuals and demonstrates their relevance for clinical SAD. Apparently the cortisol-induced increase in processing of angry faces in SAD depends on symptom severity and motivational context.

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Authors+Show Affiliations

van Peer JM
Leiden University Institute for Psychological Research, Department of Clinical, Health and Neuropsychology, Leiden University, PO-Box 9555, 2300 RB Leiden, The Netherlands. jpeer@fsw.leidenuniv.nl
Spinhoven P
No affiliation info available
van Dijk JG
No affiliation info available
Roelofs K
No affiliation info available

MeSH

AdolescentAdultAnalysis of VarianceAnti-Inflammatory AgentsAvoidance LearningDouble-Blind MethodElectroencephalographyElectrooculographyEmotionsEvoked Potentials, VisualFacial ExpressionFemaleHumansHydrocortisoneMaleMiddle AgedMotivationMovementNeuropsychological TestsPattern Recognition, VisualPhobic DisordersPhotic StimulationReaction TimeSeverity of Illness IndexStatistics as TopicYoung Adult

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19428977

Citation

van Peer, Jacobien M., et al. "Cortisol-induced Enhancement of Emotional Face Processing in Social Phobia Depends On Symptom Severity and Motivational Context." Biological Psychology, vol. 81, no. 2, 2009, pp. 123-30.
van Peer JM, Spinhoven P, van Dijk JG, et al. Cortisol-induced enhancement of emotional face processing in social phobia depends on symptom severity and motivational context. Biol Psychol. 2009;81(2):123-30.
van Peer, J. M., Spinhoven, P., van Dijk, J. G., & Roelofs, K. (2009). Cortisol-induced enhancement of emotional face processing in social phobia depends on symptom severity and motivational context. Biological Psychology, 81(2), 123-30. https://doi.org/10.1016/j.biopsycho.2009.03.006
van Peer JM, et al. Cortisol-induced Enhancement of Emotional Face Processing in Social Phobia Depends On Symptom Severity and Motivational Context. Biol Psychol. 2009;81(2):123-30. PubMed PMID: 19428977.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cortisol-induced enhancement of emotional face processing in social phobia depends on symptom severity and motivational context. AU - van Peer,Jacobien M, AU - Spinhoven,Philip, AU - van Dijk,J Gert, AU - Roelofs,Karin, Y1 - 2009/03/28/ PY - 2008/11/06/received PY - 2009/03/10/revised PY - 2009/03/16/accepted PY - 2009/5/12/entrez PY - 2009/5/12/pubmed PY - 2009/7/25/medline SP - 123 EP - 30 JF - Biological psychology JO - Biol Psychol VL - 81 IS - 2 N2 - We investigated the effects of cortisol administration on approach and avoidance tendencies in 20 patients with social anxiety disorder (SAD). Event-related brain potentials (ERPs) were measured during a reaction time task, in which patients evaluated the emotional expression of photographs of happy and angry faces by making an approaching (flexion) or avoiding (extension) arm movement. Patients showed significant avoidance tendencies for angry but not for happy faces, both in the placebo and cortisol condition. Moreover, ERP analyses showed a significant interaction of condition by severity of social anxiety on early positive (P150) amplitudes during avoidance compared to approach, indicating that cortisol increases early processing of social stimuli (in particular angry faces) during avoidance. This result replicates previous findings from a non-clinical sample of high anxious individuals and demonstrates their relevance for clinical SAD. Apparently the cortisol-induced increase in processing of angry faces in SAD depends on symptom severity and motivational context. SN - 1873-6246 UR - https://www.unboundmedicine.com/medline/citation/19428977/Cortisol_induced_enhancement_of_emotional_face_processing_in_social_phobia_depends_on_symptom_severity_and_motivational_context_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0301-0511(09)00070-2 DB - PRIME DP - Unbound Medicine ER -