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Outcome among patients with acute renal failure needing continuous renal replacement therapy: A single center study.
Hemodial Int. 2009 Apr; 13(2):205-14.HI

Abstract

Outcome of acute renal failure (ARF) and use of continuous renal replacement therapy (CRRT) have shown a consistently high mortality. (1) Evaluate the short-term patient survival. (2) Evaluate dialysis-free survival. (3) Evaluate risk factors associated with overall survival and the continued need for intermittent dialysis. We identified adults (>/=18 years) needing CRRT, treated in the critical care units of Froedtert Medical and Lutheran Hospital from January 1, 2003 till December 31, 2005. Patients were divided into two major groups needing CRRT, end stage renal disease (ESRD) (chronic dialysis) and non-ESRD with ARF. Continuous renal replacement therapy was performed with an average of 2 L replacement fluid exchanges/h. Sigma stat software was used for analysis. Comparison was done for noncontinuous variables by chi-square and t test for categorical and continuous variables, respectively. A total of 110 (ESRD 24/non-ESRD 86) patients received CRRT during study period. Over all in-hospital mortality among non-ESRD patients was 63% vs. 46% for ESRD. Among non-ESRD patients who survived, 47% needed intermittent hemodialysis on intensive care unit discharge and 28% continued to need hemodialysis at last follow-up. Among non-ESRD patients alive at discharge, those who were dialysis dependent on last follow-up were older (64.5) than those who did not require dialysis on last follow-up (58.4) P=0.347. Non-ESRD patients who died were in the hospital for an average of 17.5 days compared with 29 days for those who were discharged from the hospital. Patients with ARF needing CRRT have high in-hospital mortality. A significant percentage of patients remained dialysis dependant on last follow-up.

Authors+Show Affiliations

Division of Nephrology, Medical College of Wisconsin & Clement J. Zablocki VAMC, Milwaukee, Wisconsin 53226, USA. shussain@mcw.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19432695

Citation

Hussain, Syed, et al. "Outcome Among Patients With Acute Renal Failure Needing Continuous Renal Replacement Therapy: a Single Center Study." Hemodialysis International. International Symposium On Home Hemodialysis, vol. 13, no. 2, 2009, pp. 205-14.
Hussain S, Piering W, Mohyuddin T, et al. Outcome among patients with acute renal failure needing continuous renal replacement therapy: A single center study. Hemodial Int. 2009;13(2):205-14.
Hussain, S., Piering, W., Mohyuddin, T., Saleh, M., Zhu, Y. R., Hannan, M., Hanan, M., & Cohen, E. (2009). Outcome among patients with acute renal failure needing continuous renal replacement therapy: A single center study. Hemodialysis International. International Symposium On Home Hemodialysis, 13(2), 205-14. https://doi.org/10.1111/j.1542-4758.2009.00342.x
Hussain S, et al. Outcome Among Patients With Acute Renal Failure Needing Continuous Renal Replacement Therapy: a Single Center Study. Hemodial Int. 2009;13(2):205-14. PubMed PMID: 19432695.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outcome among patients with acute renal failure needing continuous renal replacement therapy: A single center study. AU - Hussain,Syed, AU - Piering,Walter, AU - Mohyuddin,Tayyab, AU - Saleh,Mohammad, AU - Zhu,Yong-Ran, AU - Hannan,Mary, AU - Hanan,Mary, AU - Cohen,Eric, PY - 2009/5/13/entrez PY - 2009/5/13/pubmed PY - 2009/8/15/medline SP - 205 EP - 14 JF - Hemodialysis international. International Symposium on Home Hemodialysis JO - Hemodial Int VL - 13 IS - 2 N2 - Outcome of acute renal failure (ARF) and use of continuous renal replacement therapy (CRRT) have shown a consistently high mortality. (1) Evaluate the short-term patient survival. (2) Evaluate dialysis-free survival. (3) Evaluate risk factors associated with overall survival and the continued need for intermittent dialysis. We identified adults (>/=18 years) needing CRRT, treated in the critical care units of Froedtert Medical and Lutheran Hospital from January 1, 2003 till December 31, 2005. Patients were divided into two major groups needing CRRT, end stage renal disease (ESRD) (chronic dialysis) and non-ESRD with ARF. Continuous renal replacement therapy was performed with an average of 2 L replacement fluid exchanges/h. Sigma stat software was used for analysis. Comparison was done for noncontinuous variables by chi-square and t test for categorical and continuous variables, respectively. A total of 110 (ESRD 24/non-ESRD 86) patients received CRRT during study period. Over all in-hospital mortality among non-ESRD patients was 63% vs. 46% for ESRD. Among non-ESRD patients who survived, 47% needed intermittent hemodialysis on intensive care unit discharge and 28% continued to need hemodialysis at last follow-up. Among non-ESRD patients alive at discharge, those who were dialysis dependent on last follow-up were older (64.5) than those who did not require dialysis on last follow-up (58.4) P=0.347. Non-ESRD patients who died were in the hospital for an average of 17.5 days compared with 29 days for those who were discharged from the hospital. Patients with ARF needing CRRT have high in-hospital mortality. A significant percentage of patients remained dialysis dependant on last follow-up. SN - 1492-7535 UR - https://www.unboundmedicine.com/medline/citation/19432695/Outcome_among_patients_with_acute_renal_failure_needing_continuous_renal_replacement_therapy:_A_single_center_study_ DB - PRIME DP - Unbound Medicine ER -