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Folate status in young overweight and obese women: changes associated with weight reduction and increased folate intake.
J Nutr Sci Vitaminol (Tokyo). 2009 Apr; 55(2):149-55.JN

Abstract

OBJECTIVE

To analyze folate status changes in a group of overweight/obese young women following two different weight control programs.

METHODS

Fifty-seven women (BMI=24-35 kg/m(2)) were randomly assigned to one of two slightly hypocaloric diets: diet V, in which the consumption of vegetables was increased, or diet C, in which the consumption of cereals (especially breakfast cereals) was increased. Dietetic, anthropometric and biochemical data were collected at the start of the study and again at 6 wk.

RESULTS

At the beginning of the study, the obese women (BMI>or=30 kg/m(2)) were at greater risk of showing serum folic acid concentrations of <14.9 nmol/L, even though there were no differences in folate intake between them and the women with a lower BMI. Energy intake was reduced and folate intake increased with both the V and C diets. Weight was lost as a consequence of this lower energy intake. Serum folic acid concentration increased and the plasma homocysteine concentration diminished only in those who lost >2.5 kg; this was the case of the subjects as a whole and of those who followed the C diet. Among those who lost the most weight (>2.5 kg), the chances of having an increased serum folate concentration were higher, although no significant differences were seen in folate intake with respect to women who lost less weight.

CONCLUSIONS

Following a hypocaloric diet could lead to a better folate status through increased intake, but especially among those who lose the most body weight.

Authors+Show Affiliations

Department of Nutrition, Faculty of Pharmacy, Complutense University, Madrid, Spain. rortega@farm.ucm.esNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19436141

Citation

Ortega, Rosa M., et al. "Folate Status in Young Overweight and Obese Women: Changes Associated With Weight Reduction and Increased Folate Intake." Journal of Nutritional Science and Vitaminology, vol. 55, no. 2, 2009, pp. 149-55.
Ortega RM, López-Sobaler AM, Andrés P, et al. Folate status in young overweight and obese women: changes associated with weight reduction and increased folate intake. J Nutr Sci Vitaminol. 2009;55(2):149-55.
Ortega, R. M., López-Sobaler, A. M., Andrés, P., Rodríguez-Rodríguez, E., Aparicio, A., & Perea, J. M. (2009). Folate status in young overweight and obese women: changes associated with weight reduction and increased folate intake. Journal of Nutritional Science and Vitaminology, 55(2), 149-55.
Ortega RM, et al. Folate Status in Young Overweight and Obese Women: Changes Associated With Weight Reduction and Increased Folate Intake. J Nutr Sci Vitaminol. 2009;55(2):149-55. PubMed PMID: 19436141.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Folate status in young overweight and obese women: changes associated with weight reduction and increased folate intake. AU - Ortega,Rosa M, AU - López-Sobaler,Ana M, AU - Andrés,Pedro, AU - Rodríguez-Rodríguez,Elena, AU - Aparicio,Aranzazu, AU - Perea,Jose M, PY - 2009/5/14/entrez PY - 2009/5/14/pubmed PY - 2009/7/23/medline SP - 149 EP - 55 JF - Journal of nutritional science and vitaminology JO - J. Nutr. Sci. Vitaminol. VL - 55 IS - 2 N2 - OBJECTIVE: To analyze folate status changes in a group of overweight/obese young women following two different weight control programs. METHODS: Fifty-seven women (BMI=24-35 kg/m(2)) were randomly assigned to one of two slightly hypocaloric diets: diet V, in which the consumption of vegetables was increased, or diet C, in which the consumption of cereals (especially breakfast cereals) was increased. Dietetic, anthropometric and biochemical data were collected at the start of the study and again at 6 wk. RESULTS: At the beginning of the study, the obese women (BMI>or=30 kg/m(2)) were at greater risk of showing serum folic acid concentrations of <14.9 nmol/L, even though there were no differences in folate intake between them and the women with a lower BMI. Energy intake was reduced and folate intake increased with both the V and C diets. Weight was lost as a consequence of this lower energy intake. Serum folic acid concentration increased and the plasma homocysteine concentration diminished only in those who lost >2.5 kg; this was the case of the subjects as a whole and of those who followed the C diet. Among those who lost the most weight (>2.5 kg), the chances of having an increased serum folate concentration were higher, although no significant differences were seen in folate intake with respect to women who lost less weight. CONCLUSIONS: Following a hypocaloric diet could lead to a better folate status through increased intake, but especially among those who lose the most body weight. SN - 1881-7742 UR - https://www.unboundmedicine.com/medline/citation/19436141/Folate_status_in_young_overweight_and_obese_women:_changes_associated_with_weight_reduction_and_increased_folate_intake_ L2 - http://japanlinkcenter.org/JST.JSTAGE/jnsv/55.149?from=PubMed DB - PRIME DP - Unbound Medicine ER -