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Cannabinoids in the treatment of cancer.
Cancer Lett 2009; 285(1):6-12CL

Abstract

Cannabinoids, the active components of the hemp plant Cannabis sativa, along with their endogenous counterparts and synthetic derivatives, have elicited anti-cancer effects in many different in vitro and in vivo models of cancer. While the various cannabinoids have been examined in a variety of cancer models, recent studies have focused on the role of cannabinoid receptor agonists (both CB(1) and CB(2)) in the treatment of estrogen receptor-negative breast cancer. This review will summarize the anti-cancer properties of the cannabinoids, discuss their potential mechanisms of action, as well as explore controversies surrounding the results.

Authors+Show Affiliations

Department of Pharmacology and Toxicology, University of Otago, Dunedin, New Zealand.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19442435

Citation

Alexander, Amy, et al. "Cannabinoids in the Treatment of Cancer." Cancer Letters, vol. 285, no. 1, 2009, pp. 6-12.
Alexander A, Smith PF, Rosengren RJ. Cannabinoids in the treatment of cancer. Cancer Lett. 2009;285(1):6-12.
Alexander, A., Smith, P. F., & Rosengren, R. J. (2009). Cannabinoids in the treatment of cancer. Cancer Letters, 285(1), pp. 6-12. doi:10.1016/j.canlet.2009.04.005.
Alexander A, Smith PF, Rosengren RJ. Cannabinoids in the Treatment of Cancer. Cancer Lett. 2009 Nov 18;285(1):6-12. PubMed PMID: 19442435.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cannabinoids in the treatment of cancer. AU - Alexander,Amy, AU - Smith,Paul F, AU - Rosengren,Rhonda J, Y1 - 2009/05/12/ PY - 2009/01/21/received PY - 2009/04/03/revised PY - 2009/04/03/accepted PY - 2009/5/16/entrez PY - 2009/5/16/pubmed PY - 2009/10/15/medline SP - 6 EP - 12 JF - Cancer letters JO - Cancer Lett. VL - 285 IS - 1 N2 - Cannabinoids, the active components of the hemp plant Cannabis sativa, along with their endogenous counterparts and synthetic derivatives, have elicited anti-cancer effects in many different in vitro and in vivo models of cancer. While the various cannabinoids have been examined in a variety of cancer models, recent studies have focused on the role of cannabinoid receptor agonists (both CB(1) and CB(2)) in the treatment of estrogen receptor-negative breast cancer. This review will summarize the anti-cancer properties of the cannabinoids, discuss their potential mechanisms of action, as well as explore controversies surrounding the results. SN - 1872-7980 UR - https://www.unboundmedicine.com/medline/citation/19442435/abstract/Cannabinoids_in_the_treatment_of_cancer_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0304-3835(09)00252-3 DB - PRIME DP - Unbound Medicine ER -