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Carotid atherosclerosis and the risk factors in early postmenopausal Chinese women.
Maturitas 2009; 63(3):233-9M

Abstract

OBJECTIVES

To describe the distribution of intima-media thickness (IMT) and the prevalence of plaque by carotid segments, walls and sides, and to examine their associated risk factors in asymptomatic, early postmenopausal Chinese women in Hong Kong.

METHODS

Between 2002 and 2004, the study recruited 518 postmenopausal women aged 50-64 years. They were examined by B-mode ultrasound to measure the IMT and the prevalence of plaque at the near and far walls of common carotid (CCA), bifurcation (bulb), and internal carotid (ICA) of both the left and right carotid arteries. Blood pressures, obesity indices, lipids and glucose levels, sociodemographic, medical and lifestyle factors were also obtained.

RESULTS

The mean IMT was 0.76+/-0.12 mm (range: 0.53-1.33 mm). IMT was significantly thicker on the far wall than on the near wall and differed among segments (being thickest at the bulb and the narrowest at the ICA). 21.8% had at least one plaque in the carotid artery with most of the plaque found at the bulb area. Systolic blood pressure had statistically significant relationship with IMT that were fairly homogeneous among different segments. Lipids were associated with the CCA and bulb IMT, but not the ICA IMT. Diabetes predicted only CCA IMT. Older age, higher waist-hip-ratio and low-density lipoprotein cholesterol were significant predictors of plaques at all sites combined.

CONCLUSIONS

We described the distribution of IMT and the prevalence of plaque in asymptomatic, early postmenopausal Chinese women. Associations of risk factors with IMT of different arterial segments were also observed.

Authors+Show Affiliations

Department of Community and Family Medicine, The Chinese University of Hong Kong, Hong Kong.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19443144

Citation

Yu, Ruby H Y., et al. "Carotid Atherosclerosis and the Risk Factors in Early Postmenopausal Chinese Women." Maturitas, vol. 63, no. 3, 2009, pp. 233-9.
Yu RH, Ho SC, Ho SS, et al. Carotid atherosclerosis and the risk factors in early postmenopausal Chinese women. Maturitas. 2009;63(3):233-9.
Yu, R. H., Ho, S. C., Ho, S. S., Chan, S. S., Woo, J. L., & Ahuja, A. T. (2009). Carotid atherosclerosis and the risk factors in early postmenopausal Chinese women. Maturitas, 63(3), pp. 233-9. doi:10.1016/j.maturitas.2009.03.022.
Yu RH, et al. Carotid Atherosclerosis and the Risk Factors in Early Postmenopausal Chinese Women. Maturitas. 2009 Jul 20;63(3):233-9. PubMed PMID: 19443144.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Carotid atherosclerosis and the risk factors in early postmenopausal Chinese women. AU - Yu,Ruby H Y, AU - Ho,Suzanne C, AU - Ho,Stella S Y, AU - Chan,Sophie S G, AU - Woo,Jean L F, AU - Ahuja,A T, Y1 - 2009/05/13/ PY - 2008/03/11/received PY - 2009/03/26/revised PY - 2009/03/31/accepted PY - 2009/5/16/entrez PY - 2009/5/16/pubmed PY - 2009/9/30/medline SP - 233 EP - 9 JF - Maturitas JO - Maturitas VL - 63 IS - 3 N2 - OBJECTIVES: To describe the distribution of intima-media thickness (IMT) and the prevalence of plaque by carotid segments, walls and sides, and to examine their associated risk factors in asymptomatic, early postmenopausal Chinese women in Hong Kong. METHODS: Between 2002 and 2004, the study recruited 518 postmenopausal women aged 50-64 years. They were examined by B-mode ultrasound to measure the IMT and the prevalence of plaque at the near and far walls of common carotid (CCA), bifurcation (bulb), and internal carotid (ICA) of both the left and right carotid arteries. Blood pressures, obesity indices, lipids and glucose levels, sociodemographic, medical and lifestyle factors were also obtained. RESULTS: The mean IMT was 0.76+/-0.12 mm (range: 0.53-1.33 mm). IMT was significantly thicker on the far wall than on the near wall and differed among segments (being thickest at the bulb and the narrowest at the ICA). 21.8% had at least one plaque in the carotid artery with most of the plaque found at the bulb area. Systolic blood pressure had statistically significant relationship with IMT that were fairly homogeneous among different segments. Lipids were associated with the CCA and bulb IMT, but not the ICA IMT. Diabetes predicted only CCA IMT. Older age, higher waist-hip-ratio and low-density lipoprotein cholesterol were significant predictors of plaques at all sites combined. CONCLUSIONS: We described the distribution of IMT and the prevalence of plaque in asymptomatic, early postmenopausal Chinese women. Associations of risk factors with IMT of different arterial segments were also observed. SN - 1873-4111 UR - https://www.unboundmedicine.com/medline/citation/19443144/Carotid_atherosclerosis_and_the_risk_factors_in_early_postmenopausal_Chinese_women_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0378-5122(09)00111-X DB - PRIME DP - Unbound Medicine ER -