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Progressive reduction using nicotine gum as a prelude to quitting.
Nicotine Tob Res. 2009 Jul; 11(7):847-50.NT

Abstract

INTRODUCTION

This uncontrolled study examined the outcome of a program of progressive cigarette reduction, using nicotine gum, as a prelude to complete cessation among 116 smokers (70 men, 46 women; mean age = 45.7 years, SD = 12.65; mean baseline smoking = 28.3 cigarettes/day) who sought treatment in a smokers' clinic but did not want to quit abruptly.

METHODS

Subjects participated in a two-stage program consisting of a 4-month reduction phase followed by a 6-month abstinence phase. The aim was to reduce the number of cigarettes smoked daily by at least 50% by Week 8 and to quit at the end of Week 16. During the reduction phase, subjects used nicotine gum (2 or 4 mg) to progressively decrease smoking. During the abstinence phase, subjects used any type of nicotine replacement therapy (NRT) to remain smoke free. Psychological treatment and NRT were provided at no cost to participants.

RESULTS

At Month 2, 76 subjects (68%) achieved the target of 50% reduction. At the target quit date in Week 16, 66 subjects (57%) achieved carbon monoxide-validated abstinence and 45 subjects (39%) maintained continuous abstinence at the 6-month follow-up. No symptoms of nicotine overdose were detected.

DISCUSSION

A program of progressive cigarette reduction using nicotine gum is feasible in practice and may be a useful strategy for smokers who are unable or unwilling to quit by abrupt cessation.

Authors+Show Affiliations

Smokers' Clinic, Institute of Public Health, C/ Santa Cruz del Marcenado, 9 piso 2, Madrid 28015, Spain. victorina@ctv.esNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19443787

Citation

Jiménez-Ruiz, Carlos A., et al. "Progressive Reduction Using Nicotine Gum as a Prelude to Quitting." Nicotine & Tobacco Research : Official Journal of the Society for Research On Nicotine and Tobacco, vol. 11, no. 7, 2009, pp. 847-50.
Jiménez-Ruiz CA, Ulibarri MM, Besada NA, et al. Progressive reduction using nicotine gum as a prelude to quitting. Nicotine Tob Res. 2009;11(7):847-50.
Jiménez-Ruiz, C. A., Ulibarri, M. M., Besada, N. A., Guerrero, A. C., Garcia, A. G., & Cuadrado, A. R. (2009). Progressive reduction using nicotine gum as a prelude to quitting. Nicotine & Tobacco Research : Official Journal of the Society for Research On Nicotine and Tobacco, 11(7), 847-50. https://doi.org/10.1093/ntr/ntp075
Jiménez-Ruiz CA, et al. Progressive Reduction Using Nicotine Gum as a Prelude to Quitting. Nicotine Tob Res. 2009;11(7):847-50. PubMed PMID: 19443787.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Progressive reduction using nicotine gum as a prelude to quitting. AU - Jiménez-Ruiz,Carlos A, AU - Ulibarri,Marisa M, AU - Besada,Noelia A, AU - Guerrero,Ana C, AU - Garcia,Angel G, AU - Cuadrado,Agustín R, Y1 - 2009/05/14/ PY - 2009/5/16/entrez PY - 2009/5/16/pubmed PY - 2009/9/11/medline SP - 847 EP - 50 JF - Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco JO - Nicotine Tob Res VL - 11 IS - 7 N2 - INTRODUCTION: This uncontrolled study examined the outcome of a program of progressive cigarette reduction, using nicotine gum, as a prelude to complete cessation among 116 smokers (70 men, 46 women; mean age = 45.7 years, SD = 12.65; mean baseline smoking = 28.3 cigarettes/day) who sought treatment in a smokers' clinic but did not want to quit abruptly. METHODS: Subjects participated in a two-stage program consisting of a 4-month reduction phase followed by a 6-month abstinence phase. The aim was to reduce the number of cigarettes smoked daily by at least 50% by Week 8 and to quit at the end of Week 16. During the reduction phase, subjects used nicotine gum (2 or 4 mg) to progressively decrease smoking. During the abstinence phase, subjects used any type of nicotine replacement therapy (NRT) to remain smoke free. Psychological treatment and NRT were provided at no cost to participants. RESULTS: At Month 2, 76 subjects (68%) achieved the target of 50% reduction. At the target quit date in Week 16, 66 subjects (57%) achieved carbon monoxide-validated abstinence and 45 subjects (39%) maintained continuous abstinence at the 6-month follow-up. No symptoms of nicotine overdose were detected. DISCUSSION: A program of progressive cigarette reduction using nicotine gum is feasible in practice and may be a useful strategy for smokers who are unable or unwilling to quit by abrupt cessation. SN - 1469-994X UR - https://www.unboundmedicine.com/medline/citation/19443787/Progressive_reduction_using_nicotine_gum_as_a_prelude_to_quitting_ L2 - https://academic.oup.com/ntr/article-lookup/doi/10.1093/ntr/ntp075 DB - PRIME DP - Unbound Medicine ER -