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Synthesis of functionalized indenes via cascade reaction of aziridines and propargyl alcohols.
Org Lett. 2009 Jun 18; 11(12):2615-8.OL

Abstract

A concise synthesis of functionalized indenes via the Lewis acid catalyzed cascade reaction of aziridines and propargylic alcohols has been developed. The methodology offers great potential for the synthesis of biologically active indene derivatives and related polycyclic compounds.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Wang S
Department of Chemistry, Zhejiang University, Hangzhou 310027, PR China.
Zhu Y
No affiliation info available
Wang Y
No affiliation info available
Lu P
No affiliation info available

MeSH

AlkynesAziridinesCatalysisCrystallography, X-RayIndenesMolecular StructurePolycyclic CompoundsPropanolsStereoisomerismStructure-Activity Relationship

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19449884

Citation

Wang, Shaoyin, et al. "Synthesis of Functionalized Indenes Via Cascade Reaction of Aziridines and Propargyl Alcohols." Organic Letters, vol. 11, no. 12, 2009, pp. 2615-8.
Wang S, Zhu Y, Wang Y, et al. Synthesis of functionalized indenes via cascade reaction of aziridines and propargyl alcohols. Org Lett. 2009;11(12):2615-8.
Wang, S., Zhu, Y., Wang, Y., & Lu, P. (2009). Synthesis of functionalized indenes via cascade reaction of aziridines and propargyl alcohols. Organic Letters, 11(12), 2615-8. https://doi.org/10.1021/ol901033h
Wang S, et al. Synthesis of Functionalized Indenes Via Cascade Reaction of Aziridines and Propargyl Alcohols. Org Lett. 2009 Jun 18;11(12):2615-8. PubMed PMID: 19449884.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synthesis of functionalized indenes via cascade reaction of aziridines and propargyl alcohols. AU - Wang,Shaoyin, AU - Zhu,Yuanxun, AU - Wang,Yanguang, AU - Lu,Ping, PY - 2009/5/20/entrez PY - 2009/5/20/pubmed PY - 2009/10/7/medline SP - 2615 EP - 8 JF - Organic letters JO - Org Lett VL - 11 IS - 12 N2 - A concise synthesis of functionalized indenes via the Lewis acid catalyzed cascade reaction of aziridines and propargylic alcohols has been developed. The methodology offers great potential for the synthesis of biologically active indene derivatives and related polycyclic compounds. SN - 1523-7052 UR - https://www.unboundmedicine.com/medline/citation/19449884/Synthesis_of_functionalized_indenes_via_cascade_reaction_of_aziridines_and_propargyl_alcohols_ L2 - https://doi.org/10.1021/ol901033h DB - PRIME DP - Unbound Medicine ER -