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Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose.
J Dairy Res. 2009 Aug; 76(3):317-25.JD

Abstract

Bifidogenic effect and stimulation of short chain fatty acid (SCFA) production by fractions of oligosaccharides with a DP> or =3 and Gal beta(1-6) linkages synthesised from lactose or lactulose by Pectinex Ultra SP-L and Lactozym 3000 L HP G were evaluated in human faecal slurries. Results were compared with those obtained for the commercial oligosaccharide mixture Vivinal-GOS. Quantitative real-time PCR showed that all galacto-oligosaccharide (GOS) fractions stimulated slightly higher bifidobacteria growth than lactose, lactulose and Vivinal-GOS. GOS fractions promoted the production of total SCFA and acetic acid in a similar way to Vivinal-GOS and more than glucose, lactose and lactulose. In conclusion, oligosaccharides derived from lactose and lactulose may represent a suitable alternative to lactulose for the design of new functional food ingredients.

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Authors+Show Affiliations

Cardelle-Cobas A
Instituto de Fermentaciones Industriales (CSIC), Juan de la Cierva, 3, Madrid 28006, Spain.
Fernández M
No affiliation info available
Salazar N
No affiliation info available
Martínez-Villaluenga C
No affiliation info available
Villamiel M
No affiliation info available
Ruas-Madiedo P
No affiliation info available
de los Reyes-Gavilán CG
No affiliation info available

MeSH

BifidobacteriumCarbohydrate ConformationDNA, BacterialFatty AcidsFecesFermentationHumansLactoseLactuloseOligosaccharidesPolymerase Chain ReactionProbioticsStructure-Activity Relationship

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19450367

Citation

Cardelle-Cobas, Alejandra, et al. "Bifidogenic Effect and Stimulation of Short Chain Fatty Acid Production in Human Faecal Slurry Cultures By Oligosaccharides Derived From Lactose and Lactulose." The Journal of Dairy Research, vol. 76, no. 3, 2009, pp. 317-25.
Cardelle-Cobas A, Fernández M, Salazar N, et al. Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose. J Dairy Res. 2009;76(3):317-25.
Cardelle-Cobas, A., Fernández, M., Salazar, N., Martínez-Villaluenga, C., Villamiel, M., Ruas-Madiedo, P., & de los Reyes-Gavilán, C. G. (2009). Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose. The Journal of Dairy Research, 76(3), 317-25. https://doi.org/10.1017/S0022029909004063
Cardelle-Cobas A, et al. Bifidogenic Effect and Stimulation of Short Chain Fatty Acid Production in Human Faecal Slurry Cultures By Oligosaccharides Derived From Lactose and Lactulose. J Dairy Res. 2009;76(3):317-25. PubMed PMID: 19450367.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose. AU - Cardelle-Cobas,Alejandra, AU - Fernández,María, AU - Salazar,Nuria, AU - Martínez-Villaluenga,Cristina, AU - Villamiel,Mar, AU - Ruas-Madiedo,Patricia, AU - de los Reyes-Gavilán,Clara G, Y1 - 2009/05/18/ PY - 2009/5/20/entrez PY - 2009/5/20/pubmed PY - 2009/10/24/medline SP - 317 EP - 25 JF - The Journal of dairy research JO - J Dairy Res VL - 76 IS - 3 N2 - Bifidogenic effect and stimulation of short chain fatty acid (SCFA) production by fractions of oligosaccharides with a DP> or =3 and Gal beta(1-6) linkages synthesised from lactose or lactulose by Pectinex Ultra SP-L and Lactozym 3000 L HP G were evaluated in human faecal slurries. Results were compared with those obtained for the commercial oligosaccharide mixture Vivinal-GOS. Quantitative real-time PCR showed that all galacto-oligosaccharide (GOS) fractions stimulated slightly higher bifidobacteria growth than lactose, lactulose and Vivinal-GOS. GOS fractions promoted the production of total SCFA and acetic acid in a similar way to Vivinal-GOS and more than glucose, lactose and lactulose. In conclusion, oligosaccharides derived from lactose and lactulose may represent a suitable alternative to lactulose for the design of new functional food ingredients. SN - 1469-7629 UR - https://www.unboundmedicine.com/medline/citation/19450367/Bifidogenic_effect_and_stimulation_of_short_chain_fatty_acid_production_in_human_faecal_slurry_cultures_by_oligosaccharides_derived_from_lactose_and_lactulose_ L2 - https://www.cambridge.org/core/product/identifier/S0022029909004063/type/journal_article DB - PRIME DP - Unbound Medicine ER -