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A prospective study on the association between lower urinary tract symptoms (LUTS) and erectile dysfunction: results from a large study in elderly Chinese in Southern China.
J Sex Med. 2009 Jul; 6(7):2024-31.JS

Abstract

INTRODUCTION

Although many cross-sectional studies have been conducted on the association between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED), no studies were prospective in Asia. Aim. The relationship between LUTS and ED is examined using a prospective cohort of 2000 Chinese men.

METHODS

Baseline and 4-year data from a large prospective cohort study of 2000 Chinese elderly men were analyzed. A total of 1,736 subjects were included in the current analysis after excluding those with history of bladder or prostate cancer, or urological surgery, and those who used alpha blockers or anti-androgen.

MAIN OUTCOME MEASURES

LUTS were measured at baseline by the International Prostatic Symptom Score and ED was measured using one question on impotence at the end of 4 years.

RESULTS

A dose-response relationship was observed for the relationship between baseline severity of LUTS and severity of ED at follow-up with those who had more severe LUTS at baseline with an increased odds of having more severe ED (odd ratio [OR] = 1.86, confidence interval [CI]: 1.16-2.97 for mild LUTS at baseline; OR = 2.95, CI: 1.81-4.81 for moderate LUTS at baseline; and OR = 3.82, CI: 2.00-7.27 for severe LUTS at baseline). Other baseline factors that were statistically significantly associated with ED included body mass index (OR = 1.13, CI: 1.01-1.26), hypertension (OR = 1.30, CI: 1.02-1.65) and diabetes (OR = 1.44, CI: 1.07-1.93).

CONCLUSION

The presence of LUTS is associated with ED with more severe LUTS being associated with higher degree of ED in men.

Authors+Show Affiliations

Department of Community and Family Medicine, School of Public Health, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong. yeungshanwong@cuhk.edu.hkNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19453871

Citation

Wong, Samuel Y S., et al. "A Prospective Study On the Association Between Lower Urinary Tract Symptoms (LUTS) and Erectile Dysfunction: Results From a Large Study in Elderly Chinese in Southern China." The Journal of Sexual Medicine, vol. 6, no. 7, 2009, pp. 2024-31.
Wong SY, Leung JC, Woo J. A prospective study on the association between lower urinary tract symptoms (LUTS) and erectile dysfunction: results from a large study in elderly Chinese in Southern China. J Sex Med. 2009;6(7):2024-31.
Wong, S. Y., Leung, J. C., & Woo, J. (2009). A prospective study on the association between lower urinary tract symptoms (LUTS) and erectile dysfunction: results from a large study in elderly Chinese in Southern China. The Journal of Sexual Medicine, 6(7), 2024-31. https://doi.org/10.1111/j.1743-6109.2009.01295.x
Wong SY, Leung JC, Woo J. A Prospective Study On the Association Between Lower Urinary Tract Symptoms (LUTS) and Erectile Dysfunction: Results From a Large Study in Elderly Chinese in Southern China. J Sex Med. 2009;6(7):2024-31. PubMed PMID: 19453871.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A prospective study on the association between lower urinary tract symptoms (LUTS) and erectile dysfunction: results from a large study in elderly Chinese in Southern China. AU - Wong,Samuel Y S, AU - Leung,Jason C, AU - Woo,Jean, Y1 - 2009/04/24/ PY - 2009/5/21/entrez PY - 2009/5/21/pubmed PY - 2010/9/30/medline SP - 2024 EP - 31 JF - The journal of sexual medicine JO - J Sex Med VL - 6 IS - 7 N2 - INTRODUCTION: Although many cross-sectional studies have been conducted on the association between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED), no studies were prospective in Asia. Aim. The relationship between LUTS and ED is examined using a prospective cohort of 2000 Chinese men. METHODS: Baseline and 4-year data from a large prospective cohort study of 2000 Chinese elderly men were analyzed. A total of 1,736 subjects were included in the current analysis after excluding those with history of bladder or prostate cancer, or urological surgery, and those who used alpha blockers or anti-androgen. MAIN OUTCOME MEASURES: LUTS were measured at baseline by the International Prostatic Symptom Score and ED was measured using one question on impotence at the end of 4 years. RESULTS: A dose-response relationship was observed for the relationship between baseline severity of LUTS and severity of ED at follow-up with those who had more severe LUTS at baseline with an increased odds of having more severe ED (odd ratio [OR] = 1.86, confidence interval [CI]: 1.16-2.97 for mild LUTS at baseline; OR = 2.95, CI: 1.81-4.81 for moderate LUTS at baseline; and OR = 3.82, CI: 2.00-7.27 for severe LUTS at baseline). Other baseline factors that were statistically significantly associated with ED included body mass index (OR = 1.13, CI: 1.01-1.26), hypertension (OR = 1.30, CI: 1.02-1.65) and diabetes (OR = 1.44, CI: 1.07-1.93). CONCLUSION: The presence of LUTS is associated with ED with more severe LUTS being associated with higher degree of ED in men. SN - 1743-6109 UR - https://www.unboundmedicine.com/medline/citation/19453871/A_prospective_study_on_the_association_between_lower_urinary_tract_symptoms__LUTS__and_erectile_dysfunction:_results_from_a_large_study_in_elderly_Chinese_in_Southern_China_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1743-6095(15)32580-7 DB - PRIME DP - Unbound Medicine ER -