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A comprehensive analysis of three Asiatic black bear mitochondrial genomes (subspecies ussuricus, formosanus and mupinensis), with emphasis on the complete mtDNA sequence of Ursus thibetanus ussuricus (Ursidae).
Mitochondrial DNA. 2008 Aug; 19(4):418-29.MD

Abstract

In the present paper, we describe the mitochondrial genome sequence of the Asiatic black bear (Ursus thibetanus ussuricus) with particular emphasis on the control region (CR), and compared with mitochondrial genomes on molecular relationships among the bears. The mitochondrial genome sequence of U. thibetanus ussuricus was 16,700 bp in size with mostly conserved structures (e.g. 13 protein-coding, two rRNA genes, 22 tRNA genes). The CR consisted of several typical conserved domains such as F, E, D, and C boxes, and a conserved sequence block. Nucleotide sequences and the repeated motifs in the CR were different among the bear species, and their copy numbers were also variable according to populations, even within F1 generations of U. thibetanus ussuricus. Comparative analyses showed that the CR D1 region was highly informative for the discrimination of the bear family. These findings suggest that nucleotide sequences of both repeated motifs and CR D1 in the bear family are good markers for species discriminations.

Authors+Show Affiliations

Department of Molecular and Environmental Bioscience, Graduate School, Hanyang University, Seoul, South Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19462516

Citation

Hwang, Dae-Sik, et al. "A Comprehensive Analysis of Three Asiatic Black Bear Mitochondrial Genomes (subspecies Ussuricus, Formosanus and Mupinensis), With Emphasis On the Complete mtDNA Sequence of Ursus Thibetanus Ussuricus (Ursidae)." Mitochondrial DNA, vol. 19, no. 4, 2008, pp. 418-29.
Hwang DS, Ki JS, Jeong DH, et al. A comprehensive analysis of three Asiatic black bear mitochondrial genomes (subspecies ussuricus, formosanus and mupinensis), with emphasis on the complete mtDNA sequence of Ursus thibetanus ussuricus (Ursidae). Mitochondrial DNA. 2008;19(4):418-29.
Hwang, D. S., Ki, J. S., Jeong, D. H., Kim, B. H., Lee, B. K., Han, S. H., & Lee, J. S. (2008). A comprehensive analysis of three Asiatic black bear mitochondrial genomes (subspecies ussuricus, formosanus and mupinensis), with emphasis on the complete mtDNA sequence of Ursus thibetanus ussuricus (Ursidae). Mitochondrial DNA, 19(4), 418-29.
Hwang DS, et al. A Comprehensive Analysis of Three Asiatic Black Bear Mitochondrial Genomes (subspecies Ussuricus, Formosanus and Mupinensis), With Emphasis On the Complete mtDNA Sequence of Ursus Thibetanus Ussuricus (Ursidae). Mitochondrial DNA. 2008;19(4):418-29. PubMed PMID: 19462516.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A comprehensive analysis of three Asiatic black bear mitochondrial genomes (subspecies ussuricus, formosanus and mupinensis), with emphasis on the complete mtDNA sequence of Ursus thibetanus ussuricus (Ursidae). AU - Hwang,Dae-Sik, AU - Ki,Jang-Seu, AU - Jeong,Dong-Hyuk, AU - Kim,Bo-Hyun, AU - Lee,Bae-Keun, AU - Han,Sang-Hoon, AU - Lee,Jae-Seong, PY - 2009/5/23/entrez PY - 2009/5/23/pubmed PY - 2009/6/20/medline SP - 418 EP - 29 JF - Mitochondrial DNA JO - Mitochondrial DNA VL - 19 IS - 4 N2 - In the present paper, we describe the mitochondrial genome sequence of the Asiatic black bear (Ursus thibetanus ussuricus) with particular emphasis on the control region (CR), and compared with mitochondrial genomes on molecular relationships among the bears. The mitochondrial genome sequence of U. thibetanus ussuricus was 16,700 bp in size with mostly conserved structures (e.g. 13 protein-coding, two rRNA genes, 22 tRNA genes). The CR consisted of several typical conserved domains such as F, E, D, and C boxes, and a conserved sequence block. Nucleotide sequences and the repeated motifs in the CR were different among the bear species, and their copy numbers were also variable according to populations, even within F1 generations of U. thibetanus ussuricus. Comparative analyses showed that the CR D1 region was highly informative for the discrimination of the bear family. These findings suggest that nucleotide sequences of both repeated motifs and CR D1 in the bear family are good markers for species discriminations. SN - 1940-1736 UR - https://www.unboundmedicine.com/medline/citation/19462516/A_comprehensive_analysis_of_three_Asiatic_black_bear_mitochondrial_genomes__subspecies_ussuricus_formosanus_and_mupinensis__with_emphasis_on_the_complete_mtDNA_sequence_of_Ursus_thibetanus_ussuricus__Ursidae__ DB - PRIME DP - Unbound Medicine ER -