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Microbial keratitis after corneal collagen crosslinking.
J Cataract Refract Surg. 2009 Jun; 35(6):1138-40.JC

Abstract

Several infiltrates appeared in the upper midperipheral cornea of a 29-year-old woman who had had uneventful corneal collagen crosslinking (CXL) with riboflavin and ultraviolet-A light (UVA) for the treatment of keratoconus in the right eye. Staphylococcus epidermidis keratitis was confirmed by microbiological studies, which guided treatment with topical fortified antibiotic agents. Before CXL, the best spectacle-corrected visual acuity (BSCVA) in the right eye was 20/25, the manifest refraction was -0.25 -0.25 x 125, and the anterior segment was normal under biomicroscopy. Five months after the procedure, the BSCVA was 20/22, the manifest refraction was +1.00 -2.50 x 40, and slitlamp examination revealed a mild residual haze in the upper midperipheral cornea. Collagen crosslinking with riboflavin-UVA is a minimally invasive method but traditionally requires epithelial removal, which could be a predisposing factor to bacterial keratitis.

Authors+Show Affiliations

Cornea and Refractive Surgery Section, Vissum-Instituto Oftalmológico de Alicante, and Miguel Hernández University School of Medicine, Alicante, Spain. jjpsantonja@coma.esNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19465303

Citation

Pérez-Santonja, Juan J., et al. "Microbial Keratitis After Corneal Collagen Crosslinking." Journal of Cataract and Refractive Surgery, vol. 35, no. 6, 2009, pp. 1138-40.
Pérez-Santonja JJ, Artola A, Javaloy J, et al. Microbial keratitis after corneal collagen crosslinking. J Cataract Refract Surg. 2009;35(6):1138-40.
Pérez-Santonja, J. J., Artola, A., Javaloy, J., Alió, J. L., & Abad, J. L. (2009). Microbial keratitis after corneal collagen crosslinking. Journal of Cataract and Refractive Surgery, 35(6), 1138-40. https://doi.org/10.1016/j.jcrs.2009.01.036
Pérez-Santonja JJ, et al. Microbial Keratitis After Corneal Collagen Crosslinking. J Cataract Refract Surg. 2009;35(6):1138-40. PubMed PMID: 19465303.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Microbial keratitis after corneal collagen crosslinking. AU - Pérez-Santonja,Juan J, AU - Artola,Alberto, AU - Javaloy,Jaime, AU - Alió,Jorge L, AU - Abad,José L, PY - 2008/10/09/received PY - 2009/01/21/revised PY - 2009/01/23/accepted PY - 2009/5/26/entrez PY - 2009/5/26/pubmed PY - 2009/8/15/medline SP - 1138 EP - 40 JF - Journal of cataract and refractive surgery JO - J Cataract Refract Surg VL - 35 IS - 6 N2 - Several infiltrates appeared in the upper midperipheral cornea of a 29-year-old woman who had had uneventful corneal collagen crosslinking (CXL) with riboflavin and ultraviolet-A light (UVA) for the treatment of keratoconus in the right eye. Staphylococcus epidermidis keratitis was confirmed by microbiological studies, which guided treatment with topical fortified antibiotic agents. Before CXL, the best spectacle-corrected visual acuity (BSCVA) in the right eye was 20/25, the manifest refraction was -0.25 -0.25 x 125, and the anterior segment was normal under biomicroscopy. Five months after the procedure, the BSCVA was 20/22, the manifest refraction was +1.00 -2.50 x 40, and slitlamp examination revealed a mild residual haze in the upper midperipheral cornea. Collagen crosslinking with riboflavin-UVA is a minimally invasive method but traditionally requires epithelial removal, which could be a predisposing factor to bacterial keratitis. SN - 1873-4502 UR - https://www.unboundmedicine.com/medline/citation/19465303/Microbial_keratitis_after_corneal_collagen_crosslinking_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0886-3350(09)00264-8 DB - PRIME DP - Unbound Medicine ER -