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Electrometric assessment of the effect of a zinc oxide paste in diaper dermatitis.
Int J Cosmet Sci. 2009 Oct; 31(5):369-74.IJ

Abstract

Diaper dermatitis affects nearly 50% of infants as well as some bed-ridden adults particularly in the elderly people. This condition is induced by irritation and maceration, and may be further exacerbated by Candida sp. colonization and infection. A key factor in the pathogenesis is the alteration in both the barrier function and the water-holding capacity of the stratum corneum. The purpose of this study was to assess the effects of an unmedicated zinc oxide-petrolatum paste and to observe for possible shielding and restoring effects on the water-holding capacity of the stratum corneum altered by diaper dermatitis. The paste appeared to load the hollow skin microrelief. It was inferred that this effect was responsible for a reticulated shielding effect. Compared with healthy skin and untreated diaper dermatitis, the application of the anhydrous paste resulted in a trend to normalize electrometric properties of skin reflecting the combination of transepidermal water loss and the water-holding capacity of the stratum corneum.

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Authors+Show Affiliations

Xhauflaire-Uhoda E
Laboratory of Skin Bioengineering and Imaging, Department of Dermatopathology, University Hospital of Liège, Liège, Belgium.
Henry F
No affiliation info available
Piérard-Franchimont C
No affiliation info available
Piérard GE
No affiliation info available

MeSH

Administration, TopicalAdultDiaper RashElectric ImpedanceFemaleHumansInfantMalePetrolatumSkin Physiological PhenomenaZinc Oxide

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19467034

Citation

Xhauflaire-Uhoda, E, et al. "Electrometric Assessment of the Effect of a Zinc Oxide Paste in Diaper Dermatitis." International Journal of Cosmetic Science, vol. 31, no. 5, 2009, pp. 369-74.
Xhauflaire-Uhoda E, Henry F, Piérard-Franchimont C, et al. Electrometric assessment of the effect of a zinc oxide paste in diaper dermatitis. Int J Cosmet Sci. 2009;31(5):369-74.
Xhauflaire-Uhoda, E., Henry, F., Piérard-Franchimont, C., & Piérard, G. E. (2009). Electrometric assessment of the effect of a zinc oxide paste in diaper dermatitis. International Journal of Cosmetic Science, 31(5), 369-74. https://doi.org/10.1111/j.1468-2494.2009.00505.x
Xhauflaire-Uhoda E, et al. Electrometric Assessment of the Effect of a Zinc Oxide Paste in Diaper Dermatitis. Int J Cosmet Sci. 2009;31(5):369-74. PubMed PMID: 19467034.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Electrometric assessment of the effect of a zinc oxide paste in diaper dermatitis. AU - Xhauflaire-Uhoda,E, AU - Henry,F, AU - Piérard-Franchimont,C, AU - Piérard,G E, Y1 - 2009/05/13/ PY - 2009/5/27/entrez PY - 2009/5/27/pubmed PY - 2009/11/18/medline SP - 369 EP - 74 JF - International journal of cosmetic science JO - Int J Cosmet Sci VL - 31 IS - 5 N2 - Diaper dermatitis affects nearly 50% of infants as well as some bed-ridden adults particularly in the elderly people. This condition is induced by irritation and maceration, and may be further exacerbated by Candida sp. colonization and infection. A key factor in the pathogenesis is the alteration in both the barrier function and the water-holding capacity of the stratum corneum. The purpose of this study was to assess the effects of an unmedicated zinc oxide-petrolatum paste and to observe for possible shielding and restoring effects on the water-holding capacity of the stratum corneum altered by diaper dermatitis. The paste appeared to load the hollow skin microrelief. It was inferred that this effect was responsible for a reticulated shielding effect. Compared with healthy skin and untreated diaper dermatitis, the application of the anhydrous paste resulted in a trend to normalize electrometric properties of skin reflecting the combination of transepidermal water loss and the water-holding capacity of the stratum corneum. SN - 1468-2494 UR - https://www.unboundmedicine.com/medline/citation/19467034/Electrometric_assessment_of_the_effect_of_a_zinc_oxide_paste_in_diaper_dermatitis_ L2 - https://doi.org/10.1111/j.1468-2494.2009.00505.x DB - PRIME DP - Unbound Medicine ER -