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Antimicrobial activity of selected plant species from "the Argentine Puna" against sensitive and multi-resistant bacteria.
J Ethnopharmacol. 2009 Jul 30; 124(3):499-505.JE

Abstract

AIM

The plant species reported here are traditionally used in the "Puna" or "Altiplano" of Argentina for ailments related to bacterial infections. The aim of this study was to evaluate their antimicrobial properties against a panel of sensitive and multi-resistant gram-positive and gram-negative bacteria.

MATERIALS AND METHODS

The antimicrobial activity of tinctures and aqueous extracts (Baccharis boliviensis, Chiliotrichiopsis keidelii, Chuquiraga atacamensis, Fabiana bryoides, Fabiana densa, Fabiana punensis, Frankenia triandra, Parastrephia lucida, Parastrephia lepidophylla, Parastrephia phyliciformis, Tetraglochin cristatum) was determined using the agar macrodilution and broth microdilution methods recommended by the Clinical and Laboratory Standards Institute (CLSI, formerly NCCLS). The antibiotic resistant clinical strains were isolated from nosocomial infection in human lesions of skin and soft parts.

RESULTS

The ethanolic extracts of 11 plant species inhibited the growth of one or more of the following strains: Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterobacter cloacae, Morganella morganii, Pseudomonas aeruginosa. Ethanol extracts (tinctures) of aerial parts of Baccharis, Fabiana and Parastrephia showed the highest levels of antibacterial activity on methicillin, oxacillin and gentamicin resistant Staphylococcus with MIC values from 20 to 150 microg/ml. Baccharis boliviensis and Fabiana bryoides were more active than the other plant species on Enterococcus faecalis with different phenotype. The most interesting activity on multi-resistant gram-negative strains was obtained from Chuquiraga atacamensis. Parastrephia species showed activity against Enterobacter cloacae, Pseudomonas aeruginosa and Proteus mirabilis. The ethanolic extracts exhibited stronger activity and broader spectrum of action than aqueous extracts. The extracts were bactericidal in most cases.

CONCLUSIONS

The presence of antibacterial activity in Puna plant extracts against multi-resistant bacteria give support to their traditional use for treating conditions associated with microorganisms in humans and animals and consequently seems promising for the treatment of multi-resistant bacteria.

Authors+Show Affiliations

INQUINOA (CONICET), Ayacucho 471, 4000 San Miguel de Tucumán, Argentina.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19467313

Citation

Zampini, I C., et al. "Antimicrobial Activity of Selected Plant Species From "the Argentine Puna" Against Sensitive and Multi-resistant Bacteria." Journal of Ethnopharmacology, vol. 124, no. 3, 2009, pp. 499-505.
Zampini IC, Cuello S, Alberto MR, et al. Antimicrobial activity of selected plant species from "the Argentine Puna" against sensitive and multi-resistant bacteria. J Ethnopharmacol. 2009;124(3):499-505.
Zampini, I. C., Cuello, S., Alberto, M. R., Ordoñez, R. M., D' Almeida, R., Solorzano, E., & Isla, M. I. (2009). Antimicrobial activity of selected plant species from "the Argentine Puna" against sensitive and multi-resistant bacteria. Journal of Ethnopharmacology, 124(3), 499-505. https://doi.org/10.1016/j.jep.2009.05.011
Zampini IC, et al. Antimicrobial Activity of Selected Plant Species From "the Argentine Puna" Against Sensitive and Multi-resistant Bacteria. J Ethnopharmacol. 2009 Jul 30;124(3):499-505. PubMed PMID: 19467313.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antimicrobial activity of selected plant species from "the Argentine Puna" against sensitive and multi-resistant bacteria. AU - Zampini,I C, AU - Cuello,S, AU - Alberto,M R, AU - Ordoñez,R M, AU - D' Almeida,R, AU - Solorzano,E, AU - Isla,M I, Y1 - 2009/05/23/ PY - 2009/01/23/received PY - 2009/05/04/revised PY - 2009/05/14/accepted PY - 2009/5/27/entrez PY - 2009/5/27/pubmed PY - 2009/10/15/medline SP - 499 EP - 505 JF - Journal of ethnopharmacology JO - J Ethnopharmacol VL - 124 IS - 3 N2 - AIM: The plant species reported here are traditionally used in the "Puna" or "Altiplano" of Argentina for ailments related to bacterial infections. The aim of this study was to evaluate their antimicrobial properties against a panel of sensitive and multi-resistant gram-positive and gram-negative bacteria. MATERIALS AND METHODS: The antimicrobial activity of tinctures and aqueous extracts (Baccharis boliviensis, Chiliotrichiopsis keidelii, Chuquiraga atacamensis, Fabiana bryoides, Fabiana densa, Fabiana punensis, Frankenia triandra, Parastrephia lucida, Parastrephia lepidophylla, Parastrephia phyliciformis, Tetraglochin cristatum) was determined using the agar macrodilution and broth microdilution methods recommended by the Clinical and Laboratory Standards Institute (CLSI, formerly NCCLS). The antibiotic resistant clinical strains were isolated from nosocomial infection in human lesions of skin and soft parts. RESULTS: The ethanolic extracts of 11 plant species inhibited the growth of one or more of the following strains: Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterobacter cloacae, Morganella morganii, Pseudomonas aeruginosa. Ethanol extracts (tinctures) of aerial parts of Baccharis, Fabiana and Parastrephia showed the highest levels of antibacterial activity on methicillin, oxacillin and gentamicin resistant Staphylococcus with MIC values from 20 to 150 microg/ml. Baccharis boliviensis and Fabiana bryoides were more active than the other plant species on Enterococcus faecalis with different phenotype. The most interesting activity on multi-resistant gram-negative strains was obtained from Chuquiraga atacamensis. Parastrephia species showed activity against Enterobacter cloacae, Pseudomonas aeruginosa and Proteus mirabilis. The ethanolic extracts exhibited stronger activity and broader spectrum of action than aqueous extracts. The extracts were bactericidal in most cases. CONCLUSIONS: The presence of antibacterial activity in Puna plant extracts against multi-resistant bacteria give support to their traditional use for treating conditions associated with microorganisms in humans and animals and consequently seems promising for the treatment of multi-resistant bacteria. SN - 1872-7573 UR - https://www.unboundmedicine.com/medline/citation/19467313/Antimicrobial_activity_of_selected_plant_species_from_"the_Argentine_Puna"_against_sensitive_and_multi_resistant_bacteria_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0378-8741(09)00301-8 DB - PRIME DP - Unbound Medicine ER -