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Antimicrobial and antioxidant activity of the essential oil and methanol extract of Nepeta cataria.
Pol J Microbiol. 2009; 58(1):69-76.PJ

Abstract

Catnip (Nepeta cataria) is an important medicinal herb belonging to the mint family, Lamiaceae. In this study, the in vitro antimicrobial and antioxidant activities of the essential oil and methanol extract from Nepeta cataria, and its essential oil composition were investigated. The essential oil, which has 4aalpha,7alpha,7abeta-nepetalactone (70.4%), 4aalpha,7alpha,7abeta-nepetalactone (6.0%), thymol (2.3%), and 4aalpha,7alpha, 7abeta3-nepetalactone (2.5%), as main components, exhibited activity against eleven bacteria, and twelve fungi and a yeast, C. albicans; with Minimum Inhibitory Concentrations (MIC) values ranging from 12.50 to 250 microl/ml; the methanol extract showed weaker activity. The samples were also subjected to a screening for their possible antioxidant activities by using 2.2-diphenyl-1-picrylhydrazyl (DPPH) and beta-carotene/linoleic acid assays. In DPPH assay, the extract showed slight antioxidant activity whereas the essential oil remained inactive. In the latter case, both the extract and the essential oil exerted weak activity having inhibiton ratios of linoleic acid oxidation at 16.4% and 27.0%, respectively. The weak antioxidative nature of the extract could be attributed to the low phenolic content, estimated as gallic acid equivalent at 22.6 +/- 2.07 microg/ml or 2.26%. In both systems, antioxidant capacity of BHT was determined in parallel experiments.

Authors+Show Affiliations

Health Services Vocational Training School, Ataturk University, Yenisehir-Erzurum, 25070, Turkey.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19469289

Citation

Adiguzel, Ahmet, et al. "Antimicrobial and Antioxidant Activity of the Essential Oil and Methanol Extract of Nepeta Cataria." Polish Journal of Microbiology, vol. 58, no. 1, 2009, pp. 69-76.
Adiguzel A, Ozer H, Sokmen M, et al. Antimicrobial and antioxidant activity of the essential oil and methanol extract of Nepeta cataria. Pol J Microbiol. 2009;58(1):69-76.
Adiguzel, A., Ozer, H., Sokmen, M., Gulluce, M., Sokmen, A., Kilic, H., Sahin, F., & Baris, O. (2009). Antimicrobial and antioxidant activity of the essential oil and methanol extract of Nepeta cataria. Polish Journal of Microbiology, 58(1), 69-76.
Adiguzel A, et al. Antimicrobial and Antioxidant Activity of the Essential Oil and Methanol Extract of Nepeta Cataria. Pol J Microbiol. 2009;58(1):69-76. PubMed PMID: 19469289.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antimicrobial and antioxidant activity of the essential oil and methanol extract of Nepeta cataria. AU - Adiguzel,Ahmet, AU - Ozer,Hakan, AU - Sokmen,Munevver, AU - Gulluce,Medine, AU - Sokmen,Atalay, AU - Kilic,Hamdullah, AU - Sahin,Fikrettin, AU - Baris,Ozlem, PY - 2009/5/28/entrez PY - 2009/5/28/pubmed PY - 2009/6/25/medline SP - 69 EP - 76 JF - Polish journal of microbiology JO - Pol J Microbiol VL - 58 IS - 1 N2 - Catnip (Nepeta cataria) is an important medicinal herb belonging to the mint family, Lamiaceae. In this study, the in vitro antimicrobial and antioxidant activities of the essential oil and methanol extract from Nepeta cataria, and its essential oil composition were investigated. The essential oil, which has 4aalpha,7alpha,7abeta-nepetalactone (70.4%), 4aalpha,7alpha,7abeta-nepetalactone (6.0%), thymol (2.3%), and 4aalpha,7alpha, 7abeta3-nepetalactone (2.5%), as main components, exhibited activity against eleven bacteria, and twelve fungi and a yeast, C. albicans; with Minimum Inhibitory Concentrations (MIC) values ranging from 12.50 to 250 microl/ml; the methanol extract showed weaker activity. The samples were also subjected to a screening for their possible antioxidant activities by using 2.2-diphenyl-1-picrylhydrazyl (DPPH) and beta-carotene/linoleic acid assays. In DPPH assay, the extract showed slight antioxidant activity whereas the essential oil remained inactive. In the latter case, both the extract and the essential oil exerted weak activity having inhibiton ratios of linoleic acid oxidation at 16.4% and 27.0%, respectively. The weak antioxidative nature of the extract could be attributed to the low phenolic content, estimated as gallic acid equivalent at 22.6 +/- 2.07 microg/ml or 2.26%. In both systems, antioxidant capacity of BHT was determined in parallel experiments. SN - 1733-1331 UR - https://www.unboundmedicine.com/medline/citation/19469289/Antimicrobial_and_antioxidant_activity_of_the_essential_oil_and_methanol_extract_of_Nepeta_cataria_ L2 - http://www.pjm.microbiology.pl/archive/vol5812009069.pdf DB - PRIME DP - Unbound Medicine ER -