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Hyperemesis-gravidarum-induced Wernicke's encephalopathy: serial clinical, electrophysiological and MR imaging observations.
J Neurol Sci. 2009 Sep 15; 284(1-2):214-6.JN

Abstract

Wernicke's encephalopathy (W.E.), a potentially reversible condition caused by thiamine deficiency, is usually suspected in the setting of chronic alcoholism and might not be recognized when associated with other conditions. We describe a young pregnant woman who presented with rapidly evolving ataxia, diplopia and irrelevant speech following repeated vomiting. Characteristic brain MRI and rapid response to thiamine suggested that she had W.E. possibly due to hyperemesis gravidarum. A high index of suspicion is required, since delayed or lack of treatment may lead to high morbidity and mortality.

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Authors+Show Affiliations

Netravathi M
Department of Neurology, NIMHANS, Bangalore, India.
Sinha S
No affiliation info available
Taly AB
No affiliation info available
Bindu PS
No affiliation info available
Bharath RD
No affiliation info available

MeSH

AdultFemaleHumansHyperemesis GravidarumMedulla OblongataMuscle HypotoniaNeural ConductionPeriaqueductal GrayPregnancyPregnancy ComplicationsThalamusThiamineVomitingWernicke Encephalopathy

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

19477464

Citation

Netravathi, M, et al. "Hyperemesis-gravidarum-induced Wernicke's Encephalopathy: Serial Clinical, Electrophysiological and MR Imaging Observations." Journal of the Neurological Sciences, vol. 284, no. 1-2, 2009, pp. 214-6.
Netravathi M, Sinha S, Taly AB, et al. Hyperemesis-gravidarum-induced Wernicke's encephalopathy: serial clinical, electrophysiological and MR imaging observations. J Neurol Sci. 2009;284(1-2):214-6.
Netravathi, M., Sinha, S., Taly, A. B., Bindu, P. S., & Bharath, R. D. (2009). Hyperemesis-gravidarum-induced Wernicke's encephalopathy: serial clinical, electrophysiological and MR imaging observations. Journal of the Neurological Sciences, 284(1-2), 214-6. https://doi.org/10.1016/j.jns.2009.05.004
Netravathi M, et al. Hyperemesis-gravidarum-induced Wernicke's Encephalopathy: Serial Clinical, Electrophysiological and MR Imaging Observations. J Neurol Sci. 2009 Sep 15;284(1-2):214-6. PubMed PMID: 19477464.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hyperemesis-gravidarum-induced Wernicke's encephalopathy: serial clinical, electrophysiological and MR imaging observations. AU - Netravathi,M, AU - Sinha,S, AU - Taly,A B, AU - Bindu,P S, AU - Bharath,R D, Y1 - 2009/05/27/ PY - 2009/02/08/received PY - 2009/04/21/revised PY - 2009/05/01/accepted PY - 2009/5/30/entrez PY - 2009/5/30/pubmed PY - 2009/12/16/medline SP - 214 EP - 6 JF - Journal of the neurological sciences JO - J Neurol Sci VL - 284 IS - 1-2 N2 - Wernicke's encephalopathy (W.E.), a potentially reversible condition caused by thiamine deficiency, is usually suspected in the setting of chronic alcoholism and might not be recognized when associated with other conditions. We describe a young pregnant woman who presented with rapidly evolving ataxia, diplopia and irrelevant speech following repeated vomiting. Characteristic brain MRI and rapid response to thiamine suggested that she had W.E. possibly due to hyperemesis gravidarum. A high index of suspicion is required, since delayed or lack of treatment may lead to high morbidity and mortality. SN - 1878-5883 UR - https://www.unboundmedicine.com/medline/citation/19477464/Hyperemesis_gravidarum_induced_Wernicke's_encephalopathy:_serial_clinical_electrophysiological_and_MR_imaging_observations_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-510X(09)00585-1 DB - PRIME DP - Unbound Medicine ER -